Lifeboat Foundation

a cardiac arrhythmia disorder associated with sudden death in young adults.

The findings expand possibilities for predictive risk scoring and provide new targets for therapeutic study, according to Alfred George, Jr., MD, chair and the Alfred Newton Richards Professor of Pharmacology and a co-author of the study.

“Prior to this work, there were only two genomic regions associated with Brugada syndrome risk that were identified by genome-wide studies. Data from the new study greatly expands this to 12 regions with a total of 21 genetic signals to better explain risk for Brugada syndrome,” George said. “The results also provide the basis for a polygenic risk score that can be used to assess risk in individuals.”

A recent study published in Nature Genetics identified 10 new genetic regions associated with Brugada syndrome, a cardiac arrhythmia disorder associated with sudden death in young adults.

The findings expand possibilities for predictive risk scoring and provide new targets for therapeutic study, according to Alfred George, Jr., MD, chair and the Alfred Newton Richards Professor of Pharmacology and a co-author of the study.

“Prior to this work, there were only two genomic regions associated with Brugada syndrome risk that were identified by genome-wide studies. Data from the new study greatly expands this to 12 regions with a total of 21 genetic signals to better explain risk for Brugada syndrome,” George said. “The results also provide the basis for a polygenic risk score that can be used to assess risk in individuals.”

Rén is a customizable lantern with an integrated OLED screen for users to project whatever moving images or videos they’d like.

Over the past few years, we’ve learned to prioritize what is most important to us. From going to the virtual family reunion to getting creative in the arts, we’re keeping the stuff that matters most to us extra close. Since the pandemic has transformed many of those experiences into digital ones, designers shave been getting creative in making them as large as real life, and sometimes even larger.

Designer: Merve Nur Sökme

By sending light through urine it’s possible to generate a hologram that can reveal the presence of bacteria or other signs of disease.

It’s like “Venom” or “Flubber” come to life.

Scientists have created a bizarre magnetic slime that can be remotely controlled via a magnetic field, New Scientist reports. They’re hoping the odd entity could be used to navigate narrow passages inside the human body, likely to collect objects that were mistakenly swallowed.

Of course, that’s if you’re willing to swallow this thing and have it poking around inside of you — video footage of the thing certainly doesn’t make it look appetizing. In fact, people online are already cracking potty humor jokes about it.

How can you prove that we may not be from here? The complexity of our DNA doubles every 600M years (Moores Law) so if you take the timeline back to where it intersects when life must have begun, it would be about 9.5B years ago, but the Earth has only been around for about 4.5B years. What gives?

This video is a short 1 min 12 second clip from a great documentary by Caroline Cory, “ET Contact: They Are Here”, available on iTunes:

Continue reading “Our DNA is Older Than Earth Itself — Where Did It Come From? — Oct 2, 2018” »

Scientists at Northwestern Medicine are using new advances in CRISPR gene-editing technology to uncover new biology that could lead to longer-lasting treatments and new therapeutic strategies for Human Immunodeficiency Virus (HIV).

The HIV epidemic has been overlooked during the COVID-19 pandemic but represents a critical and ongoing threat to human health with an estimated 1.5 million new infections in the last year alone.

Drug developers and research teams have been searching for cures and new treatment modalities for HIV for over 40 years but are limited by their understanding of how the virus establishes infection in the human body. How does this small, unassuming virus with only 12 proteins—and a genome only a third of the size of SARS-CoV-2—hijack the body’s cells to replicate and spread across systems?

Mojo Vision said it has created a new prototype of its Mojo Lens augmented reality contact lenses. This smart contact lens will bring “invisible computing” to life, the company believes.

The Mojo Lens prototype is a critical milestone for the company in its development, testing, and validation process, and is an innovation positioned at the intersection of smartphones, augmented reality/virtual reality, smart wearables, and health tech.

The prototype includes numerous new hardware features and technologies embedded directly into the lens — advancing its display, communications, eye tracking, and power system.

Further study of newly-sequenced portions of the genome could also help scientists better understand how humans evolved particular traits, such as the bigger brains that sent them down a genetically distinct path from their great ape ancestors.

“The things that make our frontal cortex bigger come from the genes that map in these repetitive regions,” said Evan Eichler, a professor in the department of genome sciences at the University of Washington School of Medicine and also part of the research collaborative.

Advances in genomic sequencing technology could drive a renaissance of medical breakthroughs, the researchers say.