Summary: Using data from RNA sequencing, researchers have identified three molecular subtypes of Alzheimer’s disease.
Source: Mount Sinai Hospital.
Researchers at the Icahn School of Medicine at Mount Sinai have identified three major molecular subtypes of Alzheimer’s disease (AD) using data from RNA sequencing. The study advances our understanding of the mechanisms of AD and could pave the way for developing novel, personalized therapeutics.
Gene-editing method shows promise for premature aging syndrome.
Scientists have fixed a genetic mutation in mice with progeria, a rapid aging disease. The treatment could one day be used in humans who would otherwise die in childhood.
Approximately 1 in 4 million children are diagnosed with progeria within the first two years of birth, and virtually all of these children develop health issues in childhood and adolescence that are normally associated with old age – including cardiovascular disease (heart attacks and strokes), hair loss, skeletal problems, subcutaneous fat loss and hardened skin.
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Two or three meters of DNA are packed into each of your cells, but that careful arrangement gets muddled over time, which is one reason we grow old.
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Every year, over a million people develop health care-acquired infections during their hospital stays. And around 100000 of them die from those complications.
But researchers at the University of Georgia are determined to change that, and their new study shows a promising tool for preventing infections before they happen.
Published in ACS Applied Materials and Interfaces, the study examined how an innovative coating UGA scientists developed can prevent liquids like water and blood from sticking onto surfaces. The researchers also found that the liquid-repellant coating can kill bacteria and halt blood clot formation on an object’s surface.
“We are excited to partner with Hatzolah Air on the development of our CityHawk EMS vehicle,” says Rafi Yoeli, CEO of Urban Aeronautics. “Its compact size will enable it to land in the middle of a busy city street, making it a perfect fit for medical evacuation missions by dramatically decreasing the time it takes to arrive on-scene, treat and transport sick or injured patients to appropriate medical facilities.”
For those of you unfamiliar with the CityHawk, it’s much, much more than a few concept drawings. The vehicle has been in development since the company’s inception in 2001, and an unmanned version of the CityHawk has been flying successfully for at least a year. Successfully enough, at least, to merit an agreement of, “mutual exploration by Boeing and Tactical Robotics of Autonomous Unmanned VTOL aircraft based on Urban Aeronautics … unique Fancraft™ technology.”
Andrew Steele is a scientist, writer and presenter.
Ageing is a phenomenon we’re all familiar with and is completely taken for granted as a fact of reality, but do we have to accept.
Expect to learn why curing ageing might be easier than curing cancer and all other diseases, the unfortunate truth of fasting for longevity, why the next decade will be the most exciting for lifespan research and much more…
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“I can feel touching my daughter’s hand or touching my wife’s hand, or picking up a hollow eggshell without crushing it,” Anderson says of his work with Psyonic, a startup operating out of the University of Illinois’ Research Park, in Urbana-Champaign. Psyonic expects to provide commercial prostheses with pressure sensing next year, and ones with sensory feedback sometime after that.
Technology is on the threshold of turning the unthinkable into reality. Awkward, unfeeling prostheses are morphing into mind-controlled extensions of the human body that give their wearers a sense of touch and a greater range of motion.
Along with sensory feedback, Psyonic’s rubber and silicone prosthesis uses machine learning to give its wearers intuitive control. The Modular Prosthetic Limb from Johns Hopkins University promises to deliver “humanlike” strength, thought-controlled dexterity and sensation. It’s currently in the research phase. And Icelandic company Ossur is conducting preclinical trials on mind-controlled leg and foot prostheses. These and other advances could make it dramatically easier for amputees to perform the sorts of tasks most people take for granted.
In a new study published in the journal Nature Medicine, individuals with brown fat had lower prevalences of cardiometabolic diseases, and the presence of brown fat was independently correlated with lower odds of type 2 diabetes, dyslipidemia, coronary artery disease, cerebrovascular disease, congestive heart failure and hypertension.
