The Forever Healthy Foundation has recently launched the Rejuvenation Now project, and it has just published a detailed analysis of NAD+ repletion therapies, providing the first scientific overview of this particular approach and of the supplements currently available.
One industry, two types of people
Experts at Weill Cornell Medicine in New York are using gene editing tool CRISPR to alter a string of human genetic code which is known to increase the risk of developing some cancers.
A project to use genetic engineering to prevent Lyme disease transmission to humans must be independently evaluated for long-term safety and effectiveness.
Gene editing can turn living cells into minicomputers that can read, write and perform complex calculations. The technology could track what happens inside the body over time.
DNA computers have been around since the 1990s, when researchers created DNA molecules able to perform basic mathematical functions. Instead of storing information as 0s and 1s like digital computers do, these computers store information in the molecules A, C, G and T that make up DNA.
Researchers have identified a previously unknown feature of human anatomy with implications for the function of all organs, most tissues and the mechanisms of most major diseases.
Published March 27 in Scientific Reports, a new study co-led by an NYU School of Medicine pathologist reveals that layers of the body long thought to be dense, connective tissues — below the skin’s surface, lining the digestive tract, lungs and urinary systems, and surrounding arteries, veins, and the fascia between muscles — are instead interconnected, fluid-filled compartments.
This series of spaces, supported by a meshwork of strong (collagen) and flexible (elastin) connective tissue proteins, may act like shock absorbers that keep tissues from tearing as organs, muscles, and vessels squeeze, pump, and pulse as part of daily function.
LONDON (AP) — A cheap daily pill that combines four drugs cut the risk of heart attacks, strokes and heart failure in a large study, suggesting it could be a good way to help prevent heart problems especially in poor countries.
The pills contained two blood pressure drugs, a cholesterol medicine and aspirin. Many people can’t afford or don’t stick with taking so many medicines separately, so doctors think a polypill might help. A previous study testing one in India found it lowered cholesterol and blood pressure. The new study is much larger and gives stronger evidence because it tracked heart attacks, strokes and other problems — not just risk factors.
It involved about 6,800 people in Iran, ages 50–75, some with previous heart problems and others without them. All got advice on healthy lifestyles and half also were given polypills. After five years, 6% of those in the pill group had suffered a heart attack, stroke or heart failure versus 9% of the others. That worked out to a 34% lower risk with the polypill, and a 22% lower risk after researchers took into account other heart drugs that participants were taking.
A deadly strain of salmonella that has sickened more than 250 people may not respond to the antibiotics commonly prescribed to treat the foodborne infection, according to the U.S. Centers for Disease Control and Prevention.
In its Morbidity and Mortality Weekly Report published Thursday, the CDC said that from June 2018 to March 2019, 255 people in 32 states were infected with the strain, with 60 being hospitalized and two dying from the infection.
A blood test which can detect ovarian cancer two years earlier than current methods could be used to screen women, scientists hope.
Researchers from Queen’s University Belfast have found that measuring four proteins together can pick up cancer early, when nine in 10 women will survive.
Ovarian cancer is one of the deadliest because symptoms are vague or absent so it is often not diagnosed until later stages, when the chance of surviving for five years is just 22 per cent.
But to generate the kind of long-term data set necessary for breakthroughs in precision medicine — which uses genomic, physiological and other data to tailor treatments to individuals — All of Us must retain these participants, ideally throughout their lives. That’s where genetic counselling comes in.
A firm hired by the National Institutes of Health will work with participants in a research programme that plans to sequence one million genomes.
