Lifeboat Foundation

Exercise really does influence how we age, and a new study shows how regular exercise in later life can help offset the decline of NAD+ and NAMPT, two important molecules that facilitate cellular energy production, in skeletal muscle.

NAD+ and mitochondria

The mitochondria are the power stations of the cell and provide the energy that our cells need in order to function. As we age, our mitochondria become increasingly dysfunctional and inefficient, and they produce excessive waste in the form of free radicals, which bounce around the interior of the cell, striking and damaging the cellular machinery within.

If you are a PR wizard, deep into the rejuvenation market, help us speed up the transition to a world without age-related diseases.

New potential vaccine could reduce stress and anxiety.

Research from Johns Hopkins Medicine has revealed some cases of schizophrenia can be associated with abnormal protein buildup in the brain similar to that seen in cases of Alzheimer’s and other neurodegenerative disorders. It’s hoped the discovery will lead to better diagnostic strategies identifying specific types of schizophrenia.

Sneaky molecular biology tricks bacteria into killing themselves, in place of antibiotics.

The formation of air bubbles in a liquid appears very similar to its inverse process, the formation of liquid droplets from, say, a dripping water faucet. But the physics involved is actually quite different, and while those water droplets are uniform in their size and spacing, bubble formation is typically a much more random process.

Now, a study by researchers at MIT and Princeton University shows that under certain conditions, bubbles can also be coaxed to form spheres as perfectly matched as droplets.

The new findings could have implications for the development of microfluidic devices for biomedical research and for understanding the way natural gas interacts with petroleum in the tiny pore spaces of underground rock formations, the researchers say. The findings are published today in the journal PNAS, in a paper by MIT graduate Amir Pahlavan Ph.D. ‘18, Professor Howard Stone of Princeton, MIT School of Engineering Professor of Teaching Innovation Gareth McKinley, and MIT Professor Ruben Juanes.

https://youtu.be/e5nJA8Hkvyc

Space technology expert and former Area 51 rocket designer David Adair will show you visuals and graphics of what the Aerospace Community had intended to build in space with the Shuttle program. These projects have never been seen before or announced to the public.

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New research has identified a type of bacteria found in the microbiomes of elite athletes that contributes to improved capacity for exercise. These bacteria, members of the genus Veillonella, are not found in the guts of sedentary people.

By taking a closer look at the bacteria, the researchers from Joslin Diabetes Center determined Veillonella metabolizes lactic acid produced by exercise and converts it into propionate, a short chain fatty acid. The human body then utilizes that propionate to improve exercise capacity. The results were reported today in Nature Medicine.

“Having increased exercise capacity is a strong predictor of overall health and protection against cardiovascular disease, diabetes, and overall longevity,” says Aleksandar D. Kostic Ph.D., TITLE., a co-author on the paper. “What we envision is a probiotic supplement that people can take that will increase their ability to do meaningful exercise and therefore protect them against chronic diseases including diabetes.”