Lifeboat Foundation

Outcome-based education. This is about a man who is involved in a system designed to train and assess the skills of computer programmers, but I wonder if the ideas could be applied to other types of learning.

For that matter, it strikes me that merit badges in the Boy Scouts may work along similar lines.

Nathan chose all-in, investing his entire life savings in a single stock-market exchange, and made enough money to keep the business alive. The past several years have been full of similar tests of commitment but Nathan and his business partner have weathered them all, building a groundbreaking company called Qualified.

Continue reading “EHF Fellow: Nathan Doctor” »

https://youtube.com/watch?v=jrFU5wyd_C0

A personal report from the recent Undoing Aging conference in Berlin by Nicola Bagalà. The event saw many of the leading figures in aging research and rejuvenation biotechnology attend a packed conference which celebrates its second successful year.

Last Wednesday, I landed in Berlin, Germany at around 12:30. About an hour later, I was briefly in Cafè Alex, right next to the tapering TV Tower, where I met some of my colleagues from LEAF—some of whom I had never seen in person before—as well as other volunteers and members of HEALES, our friend organization. We were all there to attend the Undoing Aging 2019 conference, which would take place over the course of the next three days, bringing together experts and researchers from all over the world to discuss the latest advances, network, and share views on the biology of aging.

Continue reading “My Experiences At Undoing Aging 2019” »

PARIS (AP) — The French government has outlined measures to ensure early diagnostic testing for young children with autism and help for them going to school.

In a statement following a Cabinet meeting Monday, the government promised that expenses linked to diagnostic testing will be fully reimbursed.

Measures include opening specific classes at preschools and elementary schools, and putting in place teacher and medical staff training and research to better understand autism, a neurodevelopmental disorder.

Major depression, obesity and chronic pain are all linked to the effects of one protein, called “FK506-binding protein 51,” or FKBP51. Until now, efforts to inhibit this target have been hampered by the difficulty of finding something specific enough to do the job and not affect similar proteins. Now a research group has developed a highly selective compound that can effectively block FKBP51 in mice, relieving chronic pain and having positive effects on diet-induced obesity and mood. The new compound also could have applications in alcoholism and brain cancer.

Wang and his colleagues found that many cancers that get switched into overdrive and boost tumor growth have jumping genes that function as a kind of stealthy “on switch.” These cryptic switches can force a gene to be turned on all the time, even though it should be off.

Mistakes in DNA are known to drive cancer growth. But a new study, from Washington University School of Medicine in St. Louis, heavily implicates a genetic phenomenon commonly known as “jumping genes” in the growth of tumors.

The study is published March 29 in the journal Nature Genetics.

Continue reading “‘Jumping genes’ drive many cancers” »

After being sold out this year with nearly 500 participants, we will be back in 2020!

Already missing us? Subscribe to the Undoing Aging YouTube channel to get notified when the UA2019 speaker presentations are released: youtube.com/c/UndoingAging

What happens when Earth’s resources run out? Well, if science fiction has taught us anything, it’s that humanity will seek a new and habitable planet somewhere in the cosmos on which to keep the species going in perpetuity. When that day comes, we’ll need a viable way to procreate and deliver children in the vastness of outer space.

Enter SpaceLife Origin, a one-of-a-kind tech company that is seeking to make it possible for humans to give birth in the vacuum of space by 2024, a goal titled “Mission Cradle.” While that is its ultimate goal, SpaceLife is also striving to become the first company to “safe-guard human ‘Seeds-of-Life’ in space [Mission Ark] by 2020 [and] make embryo conception in space feasible [Mission Lotus] by 2021,” according to its official website.

The gallery below offers a glimpse at the patent-pending “Ark” designs. Vials of human DNA will be protected within the radiation-shielded spheres that are to be kept on Earth and satellites surrounding the planet. SpaceLife Origin describes this as an insurance policy for the continuation of mankind in case a catastrophe hits and we need to leave in a hurry.

Red blood cells are amazing. They pick up oxygen from our lungs and carry it all over our body to keep us alive. The hemoglobin molecule in red blood cells transports oxygen by changing its shape in an all-or-nothing fashion. Four copies of the same protein in hemoglobin open and close like flower petals, structurally coupled to respond to each other. Using supercomputers, scientists are just starting to design proteins that self-assemble to combine and resemble life-giving molecules like hemoglobin. The scientists say their methods could be applied to useful technologies such as pharmaceutical targeting, artificial energy harvesting, ‘smart’ sensing and building materials, and more.

But the technology could also, theoretically, be used to develop placid super-soldiers.