Lifeboat Foundation

In a new study in an animal model, researchers investigate the body’s potential to replace insulin-producing cells and thus heal itself of diabetes.

A new study published in Nature Metabolism finally reveals the answer to how NMN enters the cell in order to become NAD+ and that it does not need to convert into NR to do so.

In the last few years, there has been considerable interest in restoring levels of the nicotinamide adenine dinclueotide (NAD+) coenzyme to combat age-related diseases. Evidence suggests that NAD+ systemically declines with age in a variety of organisms, including rodents and humans, which contributes to the development of many age-related diseases and metabolic conditions.

What is NAD+?

Continue reading “NMN Enters Cells via Newly Discovered Pathway” »

A new device developed by Stanford University researchers could make it easier for doctors to monitor the success of blood vessel surgery. The sensor, detailed in a paper published Jan. 8 in Nature Biomedical Engineering, monitors the flow of blood through an artery. It is biodegradable, battery-free and wireless, so it is compact and doesn’t need to be removed and it can warn a patient’s doctor if there is a blockage.

“Measurement of blood flow is critical in many medical specialties, so a wireless biodegradable sensor could impact multiple fields including vascular, transplant, reconstructive and cardiac surgery,” said Paige Fox, assistant professor of surgery and co-senior author of the paper. “As we attempt to care for patients throughout the Bay Area, Central Valley, California and beyond, this is a technology that will allow us to extend our care without requiring face-to-face visits or tests.”

Monitoring the success of surgery on blood vessels is challenging as the first sign of trouble often comes too late. By that time, the patient often needs additional surgery that carries risks similar to the original procedure. This new sensor could let doctors keep tabs on a healing vessel from afar, creating opportunities for earlier interventions.

Continue reading “Researchers create a wireless, battery-free, biodegradable blood flow sensor” »

Humanity is under threat. At least according to Sir Martin Rees, one of Britain’s most esteemed astronomers.

These two kinds of technologies enable just a few people to have a hugely wide-ranging and maybe even global cascading effect. This leads to big problems of governance because you’d like to regulate the use of these things, but enforcing regulations worldwide is very, very difficult. Think how hopeless it is to enforce the drug laws globally or the tax laws globally. To actually ensure that no one misuses these new technologies is just as difficult. I worry that we are going to have to minimize this risk by actions which lead to a great tension between privacy, liberty and security.

Do you see ways that we can use and develop these technologies in a responsible way?

Continue reading “Will humanity survive this century? Sir Martin Rees predicts ‘a bumpy ride’ ahead” »

https://youtu.be/WEqYIxtJ674

Is an American syndicated talk show airing daily on television in the U.S., Canada, Mexico, Australia, Ireland, Sweden and Finland. It debuted on September 8, 2008. The hour-long daytime program is produced by Phil McGraw and his son Jay McGraw and is distributed domestically and globally by CBS Television Distribution. The series is a spin-off of Dr. Phil and is the first talk show to be a third generation talk show spin-off, as Dr. Phil itself spun off The Oprah Winfrey Show.

Rejuvenation is a medical discipline focused on the practical reversal of the aging process.

Continue reading “The Doctors — A Way To Reverse Aging” »

A team of neuroscientists and engineers has developed a tiny, implantable device that has potential to help people with bladder problems bypass the need for medication or electronic stimulators.

The team — from Washington University School of Medicine in St. Louis, the University of Illinois at Urbana-Champaign, and the Feinberg School of Medicine at Northwestern University in Chicago — created a soft, implantable device that can detect overactivity in the bladder and then use light from tiny, biointegrated LEDs to tamp down the urge to urinate.

The device works in laboratory rats and one day may help people who suffer incontinence or frequently feel the need to urinate.

Continue reading “Tiny, implantable device uses light to treat bladder problems” »

FRIB) will be a scientific user facility for the Office of Nuclear Physics in the U.S. Department of Energy Office of Science (DOE-SC). FRIB is funded by the DOE-SC, MSU and the State of Michigan. Supporting the mission of the Office of Nuclear Physics in DOE-SC, FRIB will enable scientists to make discoveries about the properties of rare isotopes (that is, short-lived nuclei not normally found on Earth), nuclear astrophysics, fundamental interactions, and applications for society, including in medicine, homeland security, and industry.

This video — The Facility for Rare Isotope Beams at MSU — explains the history of FRIB, its role in research and education, and its future in rare-isotope discoveries. It includes an animated sequence to help viewers understand what FRIB is about.

Employment opportunities: FRIB is looking for engineers, physicists, and other talented professionals to build the world’s leading rare isotope facility.

We take a somewhat humorous look at the messaging and the comfort stories people tell themselves to distract themselves from seeing why age-related diseases and dying from them is a problem that needs solving.

Here’s what might be considered a paradox: right now, the Facebook page of Death Cafe—a place where you go to talk about death—is a rather lively place, whereas pages about life extension are comparatively rather dead places. This screenshot shows the activity of a Death Cafe post:

Continue reading “Mental Candy Is Also Unhealthy” »

We need to change how we prescribe drugs, says physician Daniel Kraft: too often, medications are dosed incorrectly, cause toxic side effects or just don’t work. In a talk and concept demo, Kraft shares his vision for a future of personalized medication, unveiling a prototype 3D printer that could design pills that adapt to our individual needs.