Lifeboat Foundation

Many scientists research the practical and immediate applications of bio molecular technology but it seems most fail to study our most important, and largest organ, our skin.

Who will officially be the first transhuman? Will it be you? Why wait decades? This article explains one approach to speeding up the process and also the challenge involved.

Defining the Object of the Goal:

Continue reading “Becoming the First Transhuman: A Call For The Right Stuff” »

Science has rightly focused on present-day concerns, trying to learn what fluorocarbon exposures mean to communities that have borne the highest exposures for the longest time. But scientists have also turned to the next generation, looking at the implications for children who are exposed in utero and again while nursing, both critical windows of development where human bodies can be uniquely vulnerable to the effects of chemical interference. Scientists know that children’s bodies bear higher PFAS levels than adults, and have since learned that PFAS exposures can interfere with whether childhood vaccines take. In young men, higher levels of exposures are associated with shortened penis length and reduced sperm counts, suggesting that PFASs might play a role in the growing global epidemic of male infertility. Research is now looking into even more fundamental questions about how PFASs participate in a host of biological processes, including liver and thyroid function, metabolism, and in reproductive and developmental outcomes.

Time-bombing the future.

Continue reading “How 20th-century synthetics altered the very fabric of us all” »

A new neurostimulator developed by engineers at UC Berkeley can listen to and stimulate electric current in the brain at the same time, potentially delivering fine-tuned treatments to patients with diseases like epilepsy and Parkinson’s.

The device, named the WAND, works like a “pacemaker for the brain,” monitoring the brain’s electrical activity and delivering electrical stimulation if it detects something amiss.

These devices can be extremely effective at preventing debilitating tremors or seizures in patients with a variety of neurological conditions. But the electrical signatures that precede a seizure or tremor can be extremely subtle, and the frequency and strength of electrical stimulation required to prevent them is equally touchy. It can take years of small adjustments by doctors before the devices provide optimal treatment.

Continue reading “Wireless ‘pacemaker for the brain’ could be new standard treatment for neurological disorders” »

Brain accumulation of the amyloid-β (Aβ) peptide is believed to be the initial event in the Alzheimer disease (AD) process. Aβ accumulation begins 15–20 years before clinical symptoms occur, mainly owing to defective brain clearance of the peptide. Over the past 20 years, we have seen intensive efforts to decrease the levels of Aβ monomers, oligomers, aggregates and plaques using compounds that decrease production, antagonize aggregation or increase brain clearance of Aβ. Unfortunately, these approaches have failed to show clinical benefit in large clinical trials involving patients with mild to moderate AD. Clinical trials in patients at earlier stages of the disease are ongoing, but the initial results have not been clinically impressive. Efforts are now being directed against Aβ oligomers, the most neurotoxic molecular species, and monoclonal antibodies directed against these oligomers are producing encouraging results. However, Aβ oligomers are in equilibrium with both monomeric and aggregated species; thus, previous drugs that efficiently removed monomeric Aβ or Aβ plaques should have produced clinical benefits. In patients with sporadic AD, Aβ accumulation could be a reactive compensatory response to neuronal damage of unknown cause, and alternative strategies, including interference with modifiable risk factors, might be needed to defeat this devastating disease.

At the Fourth Eurosymposium on Healthy Ageing, which was held in Brussels last November, Elena and I met Dr. Kris Verburgh, a medical doctor who is especially interested in biogerontology and the potential of this field of study to turn medicine on its head.

Dr. Verburgh is only about 33 years old and has already written several science books—one of which, written when he was only 16, made him the youngest science author in Europe. Another prominent interest of his is nutrition, which he believes is one of the best, if not the best, ways we currently have to slow down the march of aging and buy ourselves more time to live until the rejuvenation age; his latest book, The Longevity Code, is centered around this topic.

Dr. Verburgh is also a strong supporter of the idea that AI will play a more and more important role in research, leading the way to a not-too-far age of personalized medicine—this was one of the theses he touched upon during the panel in which he participated at EHA.

A look at the tech modifying and enhancing the human body and possibly leading us to a cyborg future.

Within days of each other back in 1998, two teams published the results of the first real-world quantum computations. But the first quantum computers weren’t computers at all. They were biochemistry equipment, relying on the same science as MRI machines.

You might think of quantum computing as a hyped-up race between computer companies to build a powerful processing device that will make more lifelike AI, revolutionize medicine, and crack the encryption that protects our data. And indeed, the prototype quantum computers of the late 1990s indirectly led to the quantum computers built by Google and IBM. But that’s not how it all began—it started with physicists tinkering with mathematics and biochemistry equipment for curiosity’s sake.

The growing understanding of the link between the gut and brain inflammation is perhaps one of the most exciting new avenues in modern medical research. An incredible new study from researchers at the University of Toronto and UC San Francisco has provided a novel insight into the gut-brain connection, revealing the intestine may be the source of immune cells found to reduce brain inflammation in multiple sclerosis (MS) sufferers.

Brain stimulation, also known as neural modulation, is emerging as a promising treatment for a wide range of diseases from depression to chronic pain to epilepsy.