Lifeboat Foundation

The process will help develop new treatments.

D esigner therapies are treatments tailored to a specific disease, and nowhere is the need greater for new therapies than in a group of nervous system disorders, known as “neurodegenerative diseases.”

Many of these diseases are common and well-known, such as Alzheimer’s or Parkinson’s disease. However, some are very rare, genetic disorders that are the consequence of a defective gene. In all these diseases, a mutant protein that misfolds causes the degeneration and death of neurons. One effective therapeutic strategy is to prevent the rogue protein from ever being made.

Spinocerebellar ataxia type 7 (SCA7) is one such disease in which nerves in different parts of the brain, including the eye, degenerate, which leads to blindness and difficulty walking, speaking, and balancing. SCA7 is dominantly inherited — which means that you just need one bad copy of the mutation to cause disease. The disease occurs when a short section of DNA that encodes ataxin-7 gene is erroneously repeated — like a word in a book printed two or three times. In this case, three chemical units of the DNA sequence — C-A-G — are repeated over and over.

Continue reading “Scientists May Have Halted Blindness Caused by This Rare Genetic Disease” »

New research suggests that exposure to childhood adversity is associated with reduced cognitive control and alterations in key brain networks. The findings, which appear in the journal Social Cognitive and Affective Neuroscience, could help explain the link between childhood adversity and depression.

“My work focuses on how we can use objective biomarkers to aid in clinical decision making,” said study author Scott A. Langenecker of the University of Utah.

“One challenging clinical decision point is what to do when individuals have recovered from a depressive episode. Do we continue treatment? Do we exercise regular check-ins? Or do we just wait and see?”

Continue reading “Childhood adversity linked to reduced inhibitory control and alterations in key brain networks” »

Kids with peanut allergies haven’t had many options, but that first-of-their-kind treatments could change that as soon as 2019.

Mayo Clinic has been using 3D printed models for over a decade to help guide surgery and treatment, education, and patient-specific simulation.

The hepatitis B virus (HBV), which spreads through blood and bodily fluids and invades liver cells, is thought to kill just under 1 million people every year around the world, mostly from cancer or scarring (cirrhosis) of the liver. HBV is less likely to be fatal than HIV, and many people who carry the virus don’t have symptoms. But because more than 250 million people live with chronic HBV infections, more than 7 times the number with HIV, its global death toll now rivals that of the more-feared virus.

Viral hepatitis is on the rise. Tackling hepatitis B in Africa is key to fighting back. Viral hepatitis is on the rise. Tackling hepatitis B in Africa is key to fighting back.

Optical fibers are then inserted through an area called the perineum, found between the testes and the anus, and directly into the prostate gland. Afterwards, the scientists turn on a red laser that is induced through the optical fibers. This process utilizes the photosensitivity of the WST11 drug and activates it. Upon activation, free radicals are released within the area, attacking and destroying the tumors. Unlike conventional treatments which might affect a general area of body cells, this treatment is localized. The nearby cells are left more or less unharmed.

Beating The Big ‘C’

The trial for this prostate cancer treatment has shown promising results. Endgadget reports that, from the 415 participating men, nearly half were rid of the malignant disease by the end of treatment. This is a huge improvement compared to conventional procedures, which only have an average success rate of about 14 percent. Of those that had cancer in remission, only six percent needed to have their affected prostate removed, which is again a stark contrast to the conventional procedures’ 30 percent.

Continue reading “Lasers Cure Nearly 50% of Patients With Prostate Cancer in New Study” »

Project for Awesome (P4A) 2018 is finally here, and you can help us to win much-needed funds at no cost to you by voting for the videos supporting our charity.

Every year, a number of charities are chosen through voting, and they each receive a sum of money based on what the fundraiser at P4A has raised. In the past, charities have received around $25,000 each, which is a considerable sum, especially for a small non-profit org such as LEAF.

Continue reading “Support the Drive to End Age-Related Diseases During Project for Awesome” »

‘Chemo brain’ affects many people who have undergone cancer treatment. What happens in the brain, and how can we reverse this effect?