Lifeboat Foundation

https://wisechase.tv/the-bugs-that-reverse-damage/

https://www.youtube.com/watch?v=Nufc8vTsbBY

ANNOUNCING THE LONGEVITY FILM COMPETITION

Please join in the crusade of eliminating age-related disease by making a video, and not only potentially help save lots of lives, but also win the first prize of $10,000! Second prize is a trip to meet Dr. Aubrey de Grey! This international (short) film competition is presented by the SENS Research Foundation, the International Longevity Alliance and Heales. The winning film will be chosen by our remarkable jury. For more information on how to compete and to sign up please visit www.longevityfilmcompetition.com

The workings of memory and learning have yet to be clarified, especially at the neural circuitry level. But researchers at Uppsala University have now, jointly with Brazilian collaborators, discovered a specific brain neuron with a central role in learning. This study, published in Neuron, may have a bearing on the potential for counteracting memory loss in Alzheimer’s disease.

When a person with dementia forgets having just eaten dinner, it is due to hippocampus damage. In contrast, the same person can describe in vivid detail a fishing trip to Norway 40 years ago. Both cases entail the use of episodic memory, the brain’s storage of events in which we have been personally involved. Dementia diseases impair the ability to form new memories, especially of events since the onset of the disease.

Researchers at Uppsala University have now, jointly with Brazilian colleagues, found certain neurons in the brain that play a crucial part in learning. The same research group had previously discovered ‘gatekeeper cells’ or, in technical parlance, OLM (Oriens-lacunosum moleculare) cells. These are located in the hippocampus, the brain area known to be active in forming new memories. The new findings from Klas Kullander’s research group show that OLM cells’ activity affects the encoding of memories in the brain.

Continue reading “Neuroscientists Improve Memory Formation, Provide Hope for Alzheimer’s Patients” »

You’re probably familiar with the feeling of slight disappointment that you may have when a good thing—say, a nice trip—is over. Just as you say that it’s too bad that the experience is already finished, someone will probably say that you had a good time nonetheless; an innocent, fitting expression to cheer you up a little bit. This phrase can be harmlessly used in a variety of circumstances, but there’s one in which it really doesn’t fit at all, yet people keep using it: when somebody dies of aging.

Not quite the same thing

In the summer of 2011, my 99-year-old grandmother was dying. She was relatively fine one day, and then on the next day, for no apparent reason, she was in bed, barely conscious. Throughout the subsequent month, she never got out of bed; all her physical necessities were being taken care of by my aunt, who was assisting her day and night. She was drip-fed for the entire month until her death. The doctors couldn’t really do anything for her, and my aunt, stressed to her limit, was torn between the sight of the non-life her mother was going through and the thought that suspending the drip feed would possibly have been the more humane choice. The drip was never suspended, and eventually, my grandmother died.

A new study published in the journal Cell Development reported that the size of an animal’s pancreatic cells relates directly to the length of its lifespan, with animals that have larger pancreatic cells living shorter lives and animals with smaller cells living longer.

Researchers studied the pancreases of 24 mammals in order to figure out how the organ grows, and what that means for an animal’s lifespan.

Last year, I got invited to a super-deluxe private resort to deliver a keynote speech to what I assumed would be a hundred or so investment bankers. It was by far the largest fee I had ever been offered for a talk — about half my annual professor’s salary — all to deliver some insight on the subject of “the future of technology.”

I’ve never liked talking about the future. The Q&A sessions always end up more like parlor games, where I’m asked to opine on the latest technology buzzwords as if they were ticker symbols for potential investments: blockchain, 3D printing, CRISPR. The audiences are rarely interested in learning about these technologies or their potential impacts beyond the binary choice of whether or not to invest in them. But money talks, so I took the gig.

After I arrived, I was ushered into what I thought was the green room. But instead of being wired with a microphone or taken to a stage, I just sat there at a plain round table as my audience was brought to me: five super-wealthy guys — yes, all men — from the upper echelon of the hedge fund world. After a bit of small talk, I realized they had no interest in the information I had prepared about the future of technology. They had come with questions of their own.

Scientists have injected spider DNA into goats to create a bulletproof material! #DCode

In a new study, researchers have attacked cancer stem cells on two fronts: glycolysis and oxidative phosphorylation.

According to a new study published in the journal Cell Metabolism, it might be possible to attack cancer by exploiting its own cellular metabolism rather than by employing drugs to kill cancerous cells directly [1].

Study summary

Continue reading “A two-way approach against cancer” »