Lifeboat Foundation

A disclaimer on the new article that I wrote: while I do think the Beta-amyloid plaque plays a key role in the development of Alzheimer’s disease I do not think it’s the only thing. I’ll be writing more on Alzheimer’s disease as I study more.

The abnormal accumulation β-amyloid peptide is the leading candidate for the cause of Alzheimer’s disease is currently ranked the 6 th leading cause of death in the United States while some statistics claim it may rank as high as the third leading cause of death.

What is Alzheimer’s disease?

Continue reading “Deletion of BACE 1 Enzyme Reverses The Symptoms of Alzheimer’s” »

It’s in a bad taste to say that other global issues are more urgent than ageing, when pretty much all global issues—ageing included—affect the life, and the quality of life, of many people.

Suppose you’re in your mid-seventies, and you find out that your aortic valve doesn’t work very well. Undergoing a replacement operation—nowadays, a relatively simple and safe procedure—is not only going to help you with your unpleasant episodes of fatigue, chest pain, and dizziness, it may well save your life, minimizing your risk of sudden cardiac arrest.

Your doctor suggests that you undergo the procedure and sends you to a surgeon for the operation; however, when you get there, the surgeon starts yelling at you that, rather than using resources to replace your valve and extend your life, we should fund initiatives to save children in poor countries, build health clinics, train midwives, and fight for equal opportunity and for women’s rights. He then goes on rambling that, until these issues are addressed, he doesn’t want to hear about extending your natural lifespan—after all, since you’re in your mid-seventies, you’re well above the world’s average lifespan; he shoos you and your family out and slams the door on you.

Continue reading “Minoring in the majors” »

Pills hailed as the first real “anti-aging” drugs inched a little closer to the market after a study found they cut the number of respiratory infections in the elderly by half.

The drugs: The pills act on an aging-related pathway called TORC1. Inhibiting this pathway “has extended life span in every species studies to date” (like mice and worms), according to Joan Mannick, who lead the study for drug giant Novartis.

Will humans live longer, too? Maybe. But that will take time to figure out. For now, what’s known is that giving people 65 and older these drugs seems to boost their immune function. Elderly people taking the drugs got about 40 percent fewer colds or bronchial infections. About 264 people got the drugs over six weeks and then were tracked for a year.

Continue reading “These anti-aging pills look like they’re actually working” »

Sexually transmitted infections can be worrisome and embarrassing, but with a few notable exceptions, most of them are quite treatable these days. Unfortunately, a new one may be on the rise. British public health officials say that Mycoplasma genitalium, a bacterial infection known as MGen for short, could soon become immune to antibiotics. If this happens, the bacterium would become what’s known as a superbug, the growing class of bacteria that have developed resistance to antibiotic drugs.

The bacterium, which can live in humans’ urinary and genital tracts, is transmitted through sexual intercourse. Women infected with the bacterium can experience pelvic inflammation and cervical inflammation, while men can experience inflammation of the urethra. An infected patient would feel these symptoms, generally speaking, as pain. Perhaps most disconcertingly, though, sometimes the infection will not cause any noticeable symptoms, meaning that an infected person can transmit it without even realizing that they’re doing so. If the infection is left untreated for too long, it can cause female patients to become sterile.

In response to the emerging threat posed by MGen, the British Association for Sexual Health and HIV on Sunday issued its draft guidelines for dealing with MGen. The organization also warned that antibiotic-resistant MGen could become much more prevalent in the coming years.

Continue reading “Public Health Officials Warn This STD Could Become a Superbug” »

Biologist Dan Gibson edits and programs DNA, just like coders program a computer. But his “code” creates life, giving scientists the power to convert digital information into biological material like proteins and vaccines. Now he’s on to a new project: “biological transportation,” which holds the promise of beaming new medicines across the globe over the internet. Learn more about how this technology could change the way we respond to disease outbreaks and enable us to download personalized prescriptions in our homes.

Researchers made a neural network out of DNA that can recognize handwritten numbers.

Today we have a report from Open Longevity School: Summer Camp 2018, an initiative in Russia focused on developing a personal health and longevity strategy, Elena Milova went to investigate.

When we ask researchers when, in their opinion, the cures for aging will be ready, we often hear an optimistic answer: 20–25 years. As a well-informed optimist, I add another 10 years to this number, because wherever the therapies appear, it will take time for them to be distributed to other countries and become affordable. I will be happy if it takes less time, but what if it doesn’t? I am nearly 40, and when I add 35 years to my current age, I vividly imagine how my reflection in the mirror will show a 75-year-old lady. Honestly, I don’t want to see my body change, and it can explain why I aspire to get first-hand information about any means to slow down aging as soon as possible. Evidence-based information, of course.

Before I tell you my story of discovering how to control my aging, I must provide a disclaimer. This article does not contain any medical recommendations. The websites of the projects I will tell you about, once again, do not contain medical recommendations and cannot be independently used to make health decisions. The experience I will share, and the activities of the projects I will tell you about, are aimed at teaching you about the existing scientific knowledge about aging and interventions that have the potential to change the way we age. Whatever you decide to implement in your everyday life, please talk to your medical advisor first.

Continue reading “Open Longevity School: Summer Camp 2018” »

This report covers the 11th edition of the EU-funded MicroNanoBio Systems cluster annual MNBS Bioelectronics Workshop, which took place in Amsterdam at the Beurs van Berlage on 12th-13th December 2017 and was included as part of the International Micro Nano Conference 2017, of which the main topics were Microfluidics and Analytical Systems, Fabrication and Characterization at the Nanoscale, and Organ-on-a-Chip.

Synthetic biologists are the computer programmers of biology. Their code? DNA.

The whole enterprise sounds fantastical: you insert new snippets of DNA code—in the form of a chain of A, T, C, G letters—into an organism, and bam! Suddenly you have bacteria that can make anti-malaria drugs or cells that can solve complicated logic problems like a computer.

Except it’s not that simple. The basis of synthetic biology is DNA—often a lot of it, in the form of many genes. Making an average gene from scratch costs several hundreds of dollars and weeks of time. Imagine a programmer taking a month to type a new line of code, and you’ll likely understand a synthetic biologist’s frustration.

Continue reading “New DNA Synthesis Method Could Soon Build a Genome in a Day” »