Lifeboat Foundation

Researchers have created a new molecule — IMP-1088 — that can render the human body inhospitable for certain viruses. The tests carried out show it can block several strains of rhinovirus, which is the main cause of the common cold.

Researchers at the University of Alabama at Birmingham have shown—for the first time—that established lung fibrosis can be reversed using a drug treatment that targets cell metabolism.

This novel finding, reported in the journal Nature Medicine, is important because, despite significant advances to reveal the pathological mechanisms of persistent fibrosis, effective treatment interventions are lacking.

Pulmonary fibrosis can develop after lung injuries like infections, radiation or chemotherapy, or it can have an unknown cause, as in idiopathic pulmonary fibrosis, or IPF is a progressive, and ultimately fatal, lung disorder that strikes more than 150,000 patients a year in the United States and more than 5 million worldwide.

Continue reading “Metformin reverses established lung fibrosis” »

Senolytics have been in the news a great deal ever since van Deursen and his team conducted a landmark 2011 study showing that removing senescent cells could delay age-related ill health in mice [1]. Since then, interest in what was once a niche topic has continued to grow at an ever-increasing pace. Now, there are many researchers engaged in exploring senescent cells and their role in aging and disease.

Lately, there has been enthusiastic interest in developing therapies to remove these problematic senescent cells, but are there potentially better ways to deal with senescent cells beyond periodically purging them with senolytic drugs and therapies?

LEAF’s monthly rejuvenation roundup is out!

July is here, and our upcoming conference in New York City is only a handful of days away! If you haven’t done so already, go and get your ticket now so that you can enjoy the June roundup fully relaxed, knowing that your seat is secured.

About our NYC conference

Continue reading “Rejuvenation Roundup June 2018” »

Google sister company Calico and drug giant AbbVie are chipping in another $1 billion to cure diseases associated with aging, the companies said Tuesday.

Now the startup behind it claims to have the cure to rising healthcare costs, with a blend of medical advice from humans and AI.

Babylon Health’s AI-powered robo-docs could save insurers and governments billions.

Ali Parsa’s AI-powered robo-docs could save insurers and governments billions. He’s already transformed a swathe of Britain’s socialized healthcare system, now he’s bringing it to the United States.

A being that can consciously alter its own DNA via technological intervention (i.e. cybernetic means) is what our Second Womb has been nurturing. We have used civilization to protect ourselves while we crack the code of our biological being. We started in the womb of the cave. Then moved on to the womb of the hut. Then the village, the city, and the state. All thew hile, we have been tinkering with our own DNA and the DNA of other species. To me, this is the real posthuman or transhuman — it is the creature that is actively editing its own biological blueprint through tech. This is what we’ve been doing since we started augmenting our bodies with clothing and animal skins. We’ve been modifying our ability to endure the slings and arrows of the cosmos.

What is human civilization? It is difficult to assert that other animals do not create their own civilizations — termites for instance meet some criteria for being categorized as cyborgs (building temperature-controlled mega structures). Animals communicate, express feelings, and have personalities. Octopi arrange furniture for would-be mates. Others engage in mating rituals. Some mourn the dead. Birds can solve simple math. Critters scheme, enterprise, forge bonds, and even produce art. What do we do that animals do not?

To our credit, we are the only animals that record, share, and develop history upon structures and materials outside of our bodies. We harness energy for massive projects. We farm, but again, so do leaf-cutter ants. But we create genetically novel vegetables and animals. We alter the global climate. Our enterprises are global, and given time and opportunity, our projects will eventually become exostellar. We do all this rather ferociously. Human history is a rather short explosion of civilization-building activities, and yet it might already have irrevocably altered the future of all life on this planet. No other creature has created a circumstance quite like that of human beings and our anthropocene project. For instance, unless we clean up the environment, the next few generations of plant and animal life are going to have be extremely resilient to radiation, Styrofoam, plastics, and other run-offs squeezed out from the human project. That is just a fact of life now on earth.

Continue reading “Human Civilization is our Second Womb for Birthing Transhumans” »

One day, 3D bioprinting will be used for printing out entire new organs to replace our old, knackered ones. This week, Chicago-based biotech startup Biolife4D announced a milestone on the road to this goal: Its ability to bioprint human cardiac tissue. Here’s why that’s important.