Lifeboat Foundation

The first clinical trials are slated to begin in the U.S. and Europe while others are stalled.

Just three years ago, the idea of wiping out disease-causing mosquitoes using gene drives seemed a distant theoretical possibility. Now it’s in reach.

NEW YORK (Reuters) — The early hope that stem cell therapy would make the paralyzed walk, the blind see and cure diabetes have given way to a long list of failures, highlighted by early stem cell champion Geron Corp abandoning the field in 2011.

But two small companies, Athersys Inc and Mesoblast Ltd, are beginning final stage trials in hundreds of patients that they — along with loyal investors — say could change the course of devastating stroke and heart failure.

Both have overcome major hurdles to manufacturing stem cell treatments on a large scale that are off-the-shelf products derived from healthy donor bone marrow and do not face immune system rejection issues.

Continue reading “Tiny stem cell companies close in on major heart disease goals” »

The topic of healthspan is increasingly being raised in the popular media, but what does it really mean? Simply put, healthspan means the period of your life in which you remain healthy and free from age-related diseases. The Roman poet Virgil once said “The greatest wealth is health”, so the concept of healthspan was something valued as far back in time as then.

Today, we are going to take a look at how we have been trying to increase human healthspan in the past and what science is doing now to take us to new frontiers of health through a new approach to medicine called rejuvenation biotechnology.

So, why is healthspan becoming such a popular saying, and why is it appearing frequently in articles and in other media now? Quite simply, the advances in our understanding of the aging processes and our ability to do something about them has reached the point at which taking measures to increase healthspan is now plausible.

The genetic atlas revealed new information about health risks, ancient political borders, and the influence of Vikings.

Learn how your family history is connected to the human journey with National Geographic’s Geno 2.0 DNA ancestry kit.

A new “DNA atlas” of Ireland is revealing some of the surprising ways historic kingdoms have influenced populations on the island—and it offers the first genetic evidence that Vikings intermingled with ancient Irish peoples.

Continue reading “Irish Ancestry Surprises Revealed by New DNA Map” »

https://www.youtube.com/watch?v=tIVNjCpqCaY&feature=share

Brendan John Frey FRSC (born 29 August 1968) is a Canadian-born machine learning and genome biology researcher, known mainly for his work on factor graphs, the wake-sleep algorithm for deep learning, and using machine learning to model genome biology and understand genetic disorders. He founded Deep Genomics and is currently its CEO, and he is a Professor of Engineering and Medicine at the University of Toronto. He co-developed a new computational approach to identifying the genetic determinants of disease, was one of the first researchers to successfully train a deep neural network, and was a pioneer in the introduction of iterative message-passing algorithms.

Frey studied computer engineering and physics at the University of Calgary (BSc 1990) and the University of Manitoba (MSc 1993), and then studied neural networks and graphical models as a doctoral candidate at the University of Toronto under the supervision of Geoffrey Hinton (PhD 1997). He was an invited participant of the Machine Learning program at the Isaac Newton Institute for Mathematical Sciences in Cambridge, UK (1997) and was a Beckman Fellow at the University of Illinois at Urbana Champaign (1999).

Continue reading “Brendan Frey — Genome Reprogramming” »

https://www.youtube.com/watch?v=YOI3dkwcqpk&feature=share

Full Interview ► https://goo.gl/YYdVUH
BioViva ► http://bioviva-science.com

Liz Parrish is the Founder and CEO of BioViva Sciences USA Inc. BioViva is committed to extending healthy lifespans using gene therapy. Liz is known as “the woman who wants to genetically engineer you,” she is a humanitarian, entrepreneur and innovator and a leading voice for genetic cures. As a strong proponent of progress and education for the advancement of gene therapy, she serves as a motivational speaker to the public at large for the life sciences. She is actively involved in international educational media outreach and sits on the board of the International Longevity Alliance (ILA). She is the founder of BioTrove Investments LLC and the BioTrove Podcasts which is committed to offering a meaningful way for people to learn about and fund research in regenerative medicine. She is also the Secretary of the American Longevity Alliance (ALA) a 501©(3) nonprofit trade association that brings together individuals, companies, and organizations who work in advancing the emerging field of cellular & regenerative medicine with the aim to get governments to consider aging a disease. Parrish received two kinds of injections, which were administered outside the United States: a myostatin inhibitor, which is expected to prevent age-associated muscle loss; and a telomerase gene therapy, which is expected to lengthen telomeres, segments of DNA at the ends of chromosomes whose shortening is associated with aging and degenerative disease.
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Another bit of science fiction is coming to life as scientists develop a highly elastic and adhesive surgical glue similar to the one Ryan Gosling used to seal his wound in Blade Runner 2049.

Surgeons use sutures, staples, and wires (sometimes in combination with adhesive substances) to facilitate healing of external and internal wounds. These methods, however, are not optimal, especially for reconnecting contracting tissues like those of lungs, arteries and the heart.

Continue reading “How Superglue Made of Human Protein Heals Wounds” »

For many of us, remembering faces from 30 years ago can be something of a challenge. But cells in our immune system can remember old foes just fine, and we’ve never really been sure exactly how they manage it.

A new study has filled in missing details on the steps our body takes to remember pathogens, finally revealing the steps our immune cells take to preserve a reference library of past battles.

Scientists from the University of California, Berkeley, used a hydrogen isotope to label white blood cells inside volunteers, and tracked a specially selected virus from infection to immunity in order to record significant steps in the immune process.

Continue reading “We Finally Know How Our Immune Cells Remember Diseases For So Long” »