Lifeboat Foundation

In the last year or so we have seen remarkable progress with a number of interventions that target the aging processes to prevent and treat age-related diseases.

Senescent cell clearance has enjoyed lots of media attention and is entering human clinical trials later this year with Unity Biotechnology. We have LysoClear from Ichor Therapeutics moving towards the clinic with a therapy based on the LysoSENS approach advocated for by the SENS Research Foundation, which seeks to treat age-related blindness caused by the accumulation of waste products in the retina cells of patients. Dr. David Sinclair is moving into human trials this year with a therapy aimed at repairing DNA damage, one of the main reasons we are thought to age.

We have had amazing progress in immunotherapy, where the immune system is taught to detect cancer and other diseases far more efficiently. For instance, immunotherapy has been used to allow the immune system spot cancer that uses the same “Do not eat me” signals that healthy cells use to avoid destruction.

Starting with just a digital file, scientists manufactured the common flu virus.

Dr. Neal Barnard says: “More colorful vegetables and fruits, a 40-minute brisk walk, vitamin E and less dairy products, cheese, and milk can protect you from alzheimer’s and dementia.”

Dr. Neal Barnard has led numerous research studies investigating the effects of diet on diabetes, body weight, and chronic pain, including a groundbreaking study of dietary interventions in type 2 diabetes, funded by the National Institutes of Health. Dr. Barnard has authored over 70 scientific publications as well as 17 books.

Continue reading “More Colorful Vegetables and Fruits Can Protect You From Alzheimer’s and Dementia: Neal Barnard” »

One of the best defenses we have against viral infections is the vaccine.

Vaccines prime the body’s immune system to fight an incoming infection; they’ve been credited with the widespread eradication of smallpox and the near-eradication of polio.

There have been many major advances to vaccines since their inception in the 1700s, but there are still many diseases for which no vaccine exists.

Continue reading “9 Dangerous Diseases That Could be Prevented” »

https://www.lifespan.io/campaigns/agemeter-biomarker-scan/#reward_13

This is one of the great rewards on offer for supporting AgeMeter, a functional age biomarker system, a project endorsed by Professor Church.

https://youtube.com/watch?v=qFZr2LTTNS8

Ray Kurzweil predicts a revolution in health & medicine due to biotechnology breakthroughs.

James Bedsol interviewed Ray Kurzweil, one of the world’s leading minds on artificial intelligence, technology and futurism, in his Google office in Mountain View, CA, February 15, 2017.

Scientists in Portland, Ore., just succeeded in creating the first genetically modified human embryo in the United States, according to Technology Review. A team led by Shoukhrat Mitalipov of Oregon Health & Science University is reported to “have broken new ground both in the number of embryos experimented upon and by demonstrating that it is possible to safely and efficiently correct defective genes that cause inherited diseases.”

The U.S. team’s results follow two trials—one last year and one in April—by researchers in China who injected genetically modified cells into cancer patients. The research teams used CRISPR, a new gene-editing system derived from bacteria that enables scientists to edit the DNA of living organisms.

The era of human gene editing has begun.

Continue reading “The Era of Human Gene Editing Is Here—What Happens Next Is Critical” »

Many of you will likely already know who Professor George Church is and that he is an important and senior member of the research community engaged in treating the aging processes to prevent or reverse age-related diseases, not to mention all kinds of other applications for genetic engineering. For those who are not familiar with him a short bio follows.

George Church is a professor at Harvard & MIT, the co-author of over 425 papers, 95 patent publications and the book Regenesis. He developed the methods used for the first genome sequence back in 1994 and he was instrumental in reducing the costs since then using next generation sequencing and nanopores plus barcoding, DNA assembly from chips, genome editing, writing and re-coding.

He co-initiated the Genome projects in 1984 and 2005 to create and interpret the world’s only open-access personal precision medicine datasets. He was also involved in launching the BRAIN Initiative in 2011.