Lifeboat Foundation

Our DNA encodes a complex biological blueprint for our lives.

Every toenail, artery, and brain cell we grow is meticulously planned and executed through our DNA’s unfathomably complex genetic instructions.

Recent genetics research has focused on how DNA may affect a person’s education, a field known as ‘educational genomics’.

Continue reading “Future schools could test a student’s DNA to predict their success” »

Bioprinting has been all over the news in the past several years with headline-worthy breakthroughs like printed human skin, synthetic bones, and even a fully functional mouse thyroid gland.

3D printing paved the way for bioprinting thanks to the printers’ unique ability to recreate human tissue structures; their software can be written to ‘stack’ cells in precise patterns as directed by a digital model, and they can produce tissue in just hours and make numerous identical samples.

Despite the progress in bioprinting, however, more complex human organs continue to elude scientists, and resting near the top of the ‘more complex’ list are the kidneys.

Continue reading “Bioprinting Is One Step Closer to Making a Human Kidney” »

More progress to help stroke victims.

Researchers at The University of Manchester have discovered that a potential new drug reduces the number of brain cells destroyed by stroke and then helps to repair the damage.

A reduction in blood flow to the brain caused by stroke is a major cause of death and disability, and there are few effective treatments.

Continue reading “New drug limits and then repairs brain damage in stroke” »

Glasgow University has taken delivery of Scotland’s most powerful magnetic resonance imaging (MRI) scanner.

The £10m device was lifted into place at the new Imaging Centre of Excellence (ICE) at the city’s Queen Elizabeth University Hospital (QEUH).

A giant crane eased the 18-tonne scanner down an alleyway with inches to spare on each side, then through a hole in the wall of the new building.

Plus, a perfume that can cover your genetic tracks.

The birth of the first baby born using a technique called mitochondrial replacement, which uses DNA from three people to “correct” an inherited genetic mutation, was announced on Sept. 27.

Mitochondrial replacement or donation allows women who carry mitochondrial diseases to avoid passing them on to their child. These diseases can range from mild to life-threatening. No therapies exist and only a few drugs are available to treat them.

There are no international rules regulating this technique. Just one country, the United Kingdom, explicitly regulates the procedure. It’s a similar situation with other assisted reproductive techniques. Some countries permit these techniques and others don’t.

Continue reading “The next frontier in reproductive tourism? Genetic modification” »

Scientists have developed a new type of artificial muscle fibre based on nylon, which could one day render our future robot companions more realistic than ever.

Unlike previous synthetic muscles, this technology is cheap and simple to produce, which makes it a better option if we want our droids to be able to flex, move, and repair themselves in much the same way as flesh-and-blood people.

Continue reading “Artificial Humans Could Be Even More Realistic With These New Nylon Muscles” »

New technology driving down the cost of research and therapies!

New technology arriving that will help drive down the costs of gene therapies.

“The researchers were able to use a closed, semi-automated benchtop system to produce genetically-modified HSCs in just one night and hope that such systems will increase the availability and affordability of cell therapies”.

Continue reading “A Semi-Automated Benchtop System to Produce Genetically Modified Stem Cells: Interview with Professor Jennifer Adair” »

More developments in senescent cell signalling published this month.

Differentiated cells in a culture dish can assume a new identity when manipulated to express four transcription factors. This “reprogramming” process has sparked interest because conceivably it could be harnessed as a therapeutic strategy for tissue regeneration. Mosteiro et al. used a mouse model to study the signals that promote cell reprogramming in vivo. They found that the factors that trigger reprogramming in vitro do the same in vivo; however, they also inflict cell damage. The damaged cells enter a state of senescence and begin secreting certain factors that promote reprogramming, including an inflammatory cytokine called interleukin-6. Thus, in the physiological setting, cell senescence may create a tissue context that favors reprogramming of neighboring cells.