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Archive for the ‘biotech/medical’ category: Page 2734

May 3, 2009

Swine Flu Update: are we entering an Age of Pandemics?

Posted by in categories: biological, biotech/medical, existential risks, futurism, geopolitics, nanotechnology, space, sustainability

May 2: Many U.S. emergency rooms and hospitals crammed with people… ”Walking well” flood hospitals… Clinics double their traffic in major cities … ER rooms turn away EMT cases. — CNN

Update May 4: Confirmed cases of H1N1 virus now at 985 in 20 countries (Mexico: 590, 25 deaths) — WHO. In U.S.: 245 confirmed U.S. cases in 35 states. — CDC.

“We might be entering an Age of Pandemics… a broad array of dangerous emerging 21st-century diseases, man-made or natural, brand-new or old, newly resistant to our current vaccines and antiviral drugs…. Martin Rees bet $1,000 that bioterror or bioerror would unleash a catastrophic event claiming one million lives in the next two decades…. Why? Less forest, more contact with animals… more meat eating (Africans last year consumed nearly 700 million wild animals… numbers of chickens raised for food in China have increased 1,000-fold over the past few decades)… farmers cut down jungle, creating deforested areas that once served as barriers to the zoonotic viruses…” — Larry Brilliant, Wall Street Journal


Apr 29, 2009

DIYbio.org

Posted by in categories: biological, biotech/medical, chemistry, education, engineering, ethics, human trajectories, open access, open source

About

DIYbio is an organization that aims to help make biology a worthwhile pursuit for citizen scientists, amateur biologists, and DIY biological engineers who value openness and safety. This will require mechanisms for amateurs to increase their knowledge and skills, access to a community of experts, the development of a code of ethics, responsible oversight, and leadership on issues that are unique to doing biology outside of traditional professional settings.

What is DIYbio in 4 minutes?

Get Involved

You can read about current events and developments in the DIYbio community by reading or subscribing to the blog.

Get in contact or get involved through discussions on our mailing list, or by attending or hosting a local DIYbio meetup.

The mailing list is the best way to find out what’s happening with DIYbio right now. There is also a low-traffic announce list.

Find out about our featured projects, including our plans for public wetlabs, global FlashLab experiments, and our innovation of next-gen lab equipment on the Projects page.

Mar 23, 2009

Detecting Disease by Tattoo

Posted by in categories: biotech/medical, nanotechnology

If you ever swore to yourself (or to another) that you’d never get a tattoo, you may just want to reconsider. You may within just a couple of years have a very good reason to get one made out of “nanoink”.

As recently reported on Discovery News, “nanoink” allows for monitoring blood glucose in real-time right under the skin. It does so by using a hydrophobic nanoparticle that changes colors as glucose levels rise and fall. The ink consists of a glucose-detecting molecule, a color changing dye and a molecule that mimics glucose. These three particles continuously swish around inside a 120-nm orb. When glucose is present, the glucose-detecting molecule attaches and glows yellow; if absent, the ink turns orange.

The use of this technology has the advantage over traditional glucose monitoring, of course, in that there is a one-time needle stick for placing the tattoo over the tens of thousands of sticks that a diabetic will need to have over a lifetime.

Another advantage of nanoink tattooing: they can be removed. At least one researcher from Brown University has developed tattoo ink with microencapsulated beads coated with a polymer that when broken with a single laser treatment can simply be expelled from the body, as opposed to multiple laser removal treatments for conventional tattoos.

Continue reading “Detecting Disease by Tattoo” »

Mar 12, 2009

Crowdsourced Women’s Health Books Released by CureTogether

Posted by in categories: biological, biotech/medical, information science, open access, open source

Over 300 Women Share Experiences, Treatments for Painful, Common Chronic Conditions

CureTogether, a Health 2.0 Startup based in Silicon Valley, has released the first crowdsourced books on vulvodynia and endometriosis: two common, poorly understood conditions causing daily pain for millions of women. Assembled from the input of 190 and 137 women living with these respective conditions, “Vulvodynia Heroes” and “Endometriosis Heroes” are the product of an ongoing online research study at http://www.curetogether.com.

“Patients came together and decided what symptoms and treatments they wanted to track. They went on to diligently gather detailed, quantitative data on their bodies and experiences,” said Alexandra Carmichael, co-Founder of CureTogether. “The hope of this book is to spread awareness, reach out to people in pain who may not have heard of endometriosis, and increase interest and funding for future research.”

“These heroes are pioneers not just in investigating their own condition, but in developing self-cure practices that others can follow.”, said Gary Wolf, Contributing Editor of Wired and Blogger at The Quantified Self. “Many other women who are suffering will find this very helpful and inspiring,” said Elizabeth Rummer, MSPT at the Pelvic Health and Rehabilitation Center in San Francisco. A patient with endometriosis added, “This is great. I am just starting to really appreciate what awesome power CureTogether can have.”

Endometriosis is a painful chronic condition that affects 5–10% of women, and vulvodyna affects up to 16% of women at some point in their lives. They are two of the most active condition communities at CureTogether, with information about symptoms, treatments, and causes added by over 300 women. The books are available at http://www.curetogether.com/VHeroes and http://www.curetogether.com/EHeroes.

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Jan 13, 2009

The New Rise of Online Health Tracking

Posted by in categories: biological, biotech/medical, futurism, open source

Tracking your health is a growing phenomenon. People have historically measured and recorded their health using simple tools: a pencil, paper, a watch and a scale. But with custom spreadsheets, streaming wifi gadgets, and a new generation of people open to sharing information, this tracking is moving online. Pew Internet reports that 70–80% of Internet users go online for health reasons, and Health 2.0 websites are popping up to meet the demand.

David Shatto, an online health enthusiast, wrote in to CureTogether, a health-tracking website, with a common question: “I’m ‘healthy’ but would be interested in tracking my health online. Not sure what this means, or what a ‘healthy’ person should track. What do you recommend?”

There are probably as many answers to this question as there are people who track themselves. The basic measure that apply to most people are:
- sleep
- weight
- calories
- exercise
People who have an illness or condition will also measure things like pain levels, pain frequency, temperature, blood pressure, day of cycle (for women), and results of blood and other biometric tests. Athletes track heart rate, distance, time, speed, location, reps, and other workout-related measures.

Another answer to this question comes from Karina, who writes on Facebook: “It’s just something I do, and need to do, and it’s part of my life. So, in a nutshell, on most days I write down what I ate and drank, how many steps I walked, when I went to bed and when I woke up, my workouts and my pain/medication/treatments. I also write down various comments about meditative activities and, if it’s extreme, my mood.”

Continue reading “The New Rise of Online Health Tracking” »

Nov 25, 2008

Giant planets ignition

Posted by in categories: biotech/medical, existential risks, futurism, geopolitics, nanotechnology, nuclear weapons, rants, space

I wrote an essay on the theme of the possibility of artificial initiation and fusion explosion of giants planets and other objects of Solar system. It is not a scientific article, but an atempt to collect all nesessary information about this existential risk. I conclude that it could not be ruled out as technical possibility, and could be made later as act of space war, which could clean entire Solar system.

Where are some events which are very improbable, but which consequence could be infinitely large (e.g. black holes on LHC.) Possibility of nuclear ignition of self-containing fusion reaction in giant planets like Jupiter and Saturn which could lead to the explosion of the planet, is one of them.

Inside the giant planets is thermonuclear fuel under high pressure and at high density. This density for certain substances is above (except water, perhaps) than the density of these substances on Earth. Large quantities of the substance would not have fly away from reaction zone long enough for large energy relize. This fuel has never been involved in fusion reactions, and it remained easy combustible components, namely, deuterium, helium-3 and lithium, which have burned at all in the stars. In addition, the subsoil giant planets contain fuel for reactions, which may prompt an explosive fire — namely, the tri-helium reaction (3 He 4 = C12) and for reactions to the accession of hydrogen to oxygen, which, however, required to start them much higher temperature. Substance in the bowels of the giant planets is a degenerate form of a metal sea, just as the substance of white dwarfs, which regularly takes place explosive thermonuclear burning in the form of helium flashes and the flashes of the first type of supernova.
The more opaque is environment, the greater are the chances for the reaction to it, as well as less scattering, but in the bowels of the giant planets there are many impurities and can be expected to lower transparency. Gravitational differentiation and chemical reactions can lead to the allocation of areas within the planet that is more suitable to run the reaction in its initial stages.

The stronger will be an explosion of fuse, the greater will be amount of the initial field of burning, and the more likely that the response would be self-sustaining, as the energy loss will be smaller and the number of reaction substances and reaction times greater. It can be assumed that if at sufficiently powerful fuse the reaction will became self-sustaining.

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Oct 8, 2008

Global Catastrophic Risks: Building a Resilient Civilization

Posted by in categories: biological, biotech/medical, chemistry, cybercrime/malcode, defense, events, futurism, geopolitics, lifeboat, military, nanotechnology, nuclear weapons, robotics/AI

November 14, 2008
Computer History Museum, Mountain View, CA

http://ieet.org/index.php/IEET/eventinfo/ieet20081114/

Organized by: Institute for Ethics and Emerging Technologies, the Center for Responsible Nanotechnology and the Lifeboat Foundation

A day-long seminar on threats to the future of humanity, natural and man-made, and the pro-active steps we can take to reduce these risks and build a more resilient civilization. Seminar participants are strongly encouraged to pre-order and review the Global Catastrophic Risks volume edited by Nick Bostrom and Milan Cirkovic, and contributed to by some of the faculty for this seminar.

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Sep 19, 2008

Open Source Health Research Plan

Posted by in categories: biological, biotech/medical, lifeboat, open access, open source

Open source has emerged as a powerful set of principles for solving complex problems in fields as diverse as education and physical security. With roughly 60 million Americans suffering from a chronic health condition, traditional research progressing slowly, and personalized medicine on the horizon, the time is right to apply open source to health research. Advances in technology enabling cheap, massive data collection combined with the emerging phenomena of self quantification and crowdsourcing make this plan feasible today. We can all work together to cure disease, and here’s how.

Read more…

Sep 2, 2008

Threats to humanity – the old and the resurgent

Posted by in categories: biological, biotech/medical, geopolitics

Following is a discussion of two potential threats to humanity – one which has existed for eons, the second we have seen recently resurfacing having thought it had been laid to rest.

First, a recent story on PhysOrg describes the work researchers at Vanderbilt University have performed in isolating antibodies from elderly people who had survived the 1918 flu pandemic. This comes three years after researchers at Mount Sinai and the Armed Forces Institute of Pathology in Washington, D.C isolated the same virus which caused this outbreak from the frozen bodies of people in Alaska who had died in the pandemic.

In addition to being an impressive achievement of biomedical science, which involved isolating antibody-secreting B cells from donors and generating “immortalized” cell lines to produce large amounts of antibodies, this research also demonstrates the amazing memory the immune system has (90 years!), as well as the ability scientists have to use tissue samples from people born nearly a century ago and fashion them into a potential weapon against future similar outbreaks. Indeed, these manufactured antibodies proved effective against 1918 flu virus when tested in mice.

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Jul 30, 2008

30 days to make antibodies to limit Pandemics

Posted by in categories: biological, biotech/medical, defense, existential risks, lifeboat

Researchers have devised a rapid and efficient method for generating protein sentinels of the immune system, called monoclonal antibodies, which mark and neutralize foreign invaders.

For both ethical and practical reasons, monoclonals are usually made in mice. And that’s a problem, because the human immune system recognizes the mouse proteins as foreign and sometimes attacks them instead. The result can be an allergic reaction, and sometimes even death.

To get around that problem, researchers now “humanize” the antibodies, replacing some or all of mouse-derived pieces with human ones.

Wilson and Ahmed were interested in the immune response to vaccination. Conventional wisdom held that the B-cell response would be dominated by “memory” B cells. But as the study authors monitored individuals vaccinated against influenza, they found that a different population of B cells peaked about one week after vaccination, and then disappeared, before the memory cells kicked in. This population of cells, called antibody-secreting plasma cells (ASCs), is highly enriched for cells that target the vaccine, with vaccine-specific cells accounting for nearly 70 percent of all ASCs.

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