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Molecular toxicology is a field that investigates the interactions between chemical or biological molecules and organisms at the molecular level. In this Special Issue, we focus on the toxic effects and mechanisms of action of chemical and biological molecules, will be of great interest of readers in molecular toxicology and applied pharmacology.

Rosacea is a skin condition that causes reddened skin and rash, usually on the nose and cheeks. There is no test for rosacea, so health care providers will typically diagnose it based on the appearance of the skin and your health history. They may run tests to rule out any other conditions. Learn more from NIAMS:

What is rosacea? It is a long-term disease that causes reddened skin and pimples, usually on the face. It can also make the skin thicker and cause eye problems.

The medial patellofemoral ligament (MPFL) is the most important stabilizer of lateral dislocation of the patella. Single-limb (SL) and double-limb (DL) graft MPFL reconstructions have been increasingly used to treat recurrent patellar dislocations, but the clinical efficacy of SL versus DL graft MPFL reconstructions remains controversial owing to the inconsistent conclusions of previous studies.

The concept of biological immortality challenges the belief that death gives meaning to life and raises questions about the potential societal implications and ethical considerations of living indefinitely.

Questions to inspire discussion.

Continue reading “Biological Immortality by 2030: Implications & Predictions” »

The Sentis Brain Animation Series takes you on a tour of the brain through a series of short and sharp animations. The fourth in the series explains how our most complex organ is capable of changing throughout our lives. This inspiring animation demonstrates how we all have the ability to learn and change by rewiring our brains. Who is Sentis? We are a global team assisting individuals and organisations change their lives for the better. The human mind is our focus and we believe the mind is an individual’s most important performance tool. We are the world leaders in the application of psychology and neuroscience to safety, leadership development, and wellbeing in the workplace. The Sentis Brain Animation Series is the intellectual property of Sentis Pty Ltd and only approved for third party use under a formal licensing agreement.

Brain networks are often represented by graph models that incorporate neuroimaging data from MRI or CT scans to represent functional or structural connections within the brain. These brain graphs can be used to understand how the organ changes over time.

Traditionally, however, these models treat the brain graphs as static, which can miss or ignore underlying changes that could signal the onset of disease or neurological disorders.

A collaborative team of researchers led by Lifang He, an assistant professor of computer science and engineering at Lehigh University, recently received a $1 million grant from the National Science Foundation, with $300,000 going to Lehigh, to develop new methods for modeling the dynamics of brain graphs using artificial intelligence that will generate more accurate, interpretable, and fair predictions when it comes to disease.

Scientists have made a pivotal advancement in creating compact laser technology using organic semiconductors. This development promises diverse applications, from enhancing OLED displays to aiding in disease detection and environmental monitoring. The new laser, which emits green light in short pulses, overcomes the traditional need for an external laser in organic semiconductor lasers. Credit: SciTechDaily.com.

Scientists have achieved a breakthrough in creating an electrically driven organic semiconductor laser, paving the way for advanced and versatile laser applications.

Researchers at the University of St. Andrews are leading a significant breakthrough in a decades-long challenge to develop compact laser technology.

The advancement of higher cognitive abilities in humans is predominantly associated with the growth of the neocortex, a brain area key to conscious thinking, movement, and sensory perception. Researchers are increasingly realizing, however, that the “little brain” or cerebellum also expanded during evolution and probably contributes to the capacities unique to humans, explains Prof. Henrik Kaessmann from the Center for Molecular Biology of Heidelberg University.

His research team has – together with Prof. Dr Stefan Pfister from the Hopp Children’s Cancer Center Heidelberg – generated comprehensive genetic maps of the development of cells in the cerebella of humans, mice, and opossums. Comparisons of these data reveal both ancestral and species-specific cellular and molecular characteristics of cerebellum development spanning over 160 million years of mammalian evolution.

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Study reveals an increase in adenomas and advanced adenomas in younger adults, alongside a rise in colorectal cancer incidence in males under 50, suggesting a need for earlier screening, particularly in men.