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In the intensive care unit (ICU), critically ill patients are cared for by a multidisciplinary care team. Compassionate and caring behaviors on the part of the care team result in better outcomes for patients and their families, and care providers entering the demanding field of medicine because they wish to help people and relieve suffering. However, studies have demonstrated deficiencies in delivering compassionate health care. Evidence suggests that physicians may miss up to 90% of opportunities to respond to patients with compassion.

To determine what factors drive and enhance compassionate care behaviors in the ICU setting and which factors drain and negate caring attitudes and behaviors, Shahla Siddiqui, MD, MSc, FCCM, and a colleague conducted an observational, qualitative study of an international panel of intensive and critical . The researcher-clinicians report in PLOS ONE that while ICU physicians and nurses feel a deep moral imperative to deliver the highest level of compassionate care, pressures of capacity strain, lack of staff, lack of compassionate skills training and a heavy emphasis on electronic health record maintenance present significant hurdles to achieving that goal.

“Studies done on physician compassion from a patient perspective emphasize listening and awareness of the patient’s , which not only builds trust within the patient-physician relationship but also enhances resilience amongst the care team and prevents burnout,” said Siddiqui, an anesthesiologist at BIDMC. “Our aim was to describe compassionate behaviors in the ICU, study the factors that enhance and those that drain such behaviors with an aim to enable recommendations for practice and training.”

In 2015, European countries formulated the Sustainable Development Goals (SDG), which aimed to end TB by 2030. However, in September 2018, global leaders at the first United Nations (UN) General Assembly High-Level Meeting on the Fight Against TB agreed on an ambitious target of eradicating TB by 2022. They strategized that increased access to TB treatment and preventive measures would help achieve their goal quickly. Another measure adopted to progress the TB eradication goal was increasing the funds related to TB research and services.

An uneven progress regarding TB eradication by 2030 was observed in some European regions by the World Health Organization (WHO). Although the majority of Western European countries were on track for TB elimination, Eastern European and Central Asian countries reported a high number of incidences of drug-resistant (DR) TB.

In the European Union/European Economic Area (EU/EEA), TB prevalence is low. Based on the TB surveillance conducted in Europe, out of 30 countries, 24 reported less than 10 TB cases per 100,000 population in 2021. These countries have been encouraged to maintain this low rate and attain the pre-elimination phase of less than 10 TB cases per million population per year. A recent Eurosurveillance journal editorial discussed the progress in the EU/EEA, between 2018 and 2021, towards achieving the 2030 targets for TB elimination.

Summary: Using a new technology called The Virtual Brain, researchers are able to create personalized computerized brain models of individual patients based on their anatomy, structural connectivity, and brain dynamics.

Source: Human Brain Project.

In the current edition of The Lancet Neurology, researchers of the Human Brain Project (HBP) present the novel clinical uses of advanced brain modeling methods.

“People study cells in the context of their biology and biochemistry, but cells are also simply physical objects you can touch and feel,” Guo says. “Just like when we construct a house, we use different materials to have different properties. A similar rule must apply to cells when forming tissues and organs. But really, not much is known about this process.”

His work in cell mechanics led him to MIT, where he recently received tenure and is the Class of ’54 Career Development Associate Professor in the Department of Mechanical Engineering.

At MIT, Guo and his students are developing tools to carefully poke and prod cells, and observe how their physical form influences the growth of a tissue, organism, or disease such as cancer. His research bridges multiple fields, including cell biology, physics, and mechanical engineering, and he is working to apply the insights from cell mechanics to engineer materials for biomedical applications, such as therapies to halt the growth and spread of diseased and cancerous cells.

“Introducing the first soft material that can maintain a high enough electrical conductivity to support power hungry devices.” and self-healing.


The newest development in softbotics will have a transformative impact on robotics, electronics, and medicine. Carmel Majidi has engineered a soft material with metal-like conductivity and self-healing properties that, for the first time, can support power-hungry devices.

“Softbotics is about seamlessly integrating robotics into everyday life, putting humans at the center,” explained Majidi, a professor of mechanical engineering.

Engineers work to integrate robots into our everyday lives with the hope of improving our mobility, health, and well-being. For example, patients might one day recover from surgery at home thanks to a wearable robot monitoring aid. To integrate robots seamlessly, they need to be able to move with us, withstand damage, and have electrical functionality without being encased in a hard structure.

A new CRISPR tool corrected a genetic mutation that causes vision loss, in an experiment in mice — and its creators at the Wuhan University of Science and Technology (WUST) in China think it could be a safe way to treat countless other genetic diseases in people.

The challenge: Vision starts with light entering the eye and traveling to the retina. There, light-sensitive cells, called photoreceptors, convert light into electrical signals that are sent to the brain.

Retinitis pigmentosa is a rare — and, currently, incurable — genetic disease that can be caused by mutations in more than 100 different genes. These mutations destroy the cells of the retina, leading to vision loss, and for most people, there’s no way to stop the disease or reverse its damage (the exception is a gene therapy approved to treat mutations in the RPE65 gene).

Neuroscientist Sergiu P. Pasca has made it his life’s work to understand how the human brain builds itself — and what makes it susceptible to disease. In a mind-blowing talk laden with breakthrough science, he shows how his team figured out how to grow “organoids” and what they call brain “assembloids” — self-organizing clumps of neural tissue derived from stem cells that have shown the ability to form circuits — and explains how these miniature parts of the nervous system are bringing us closer to demystifying the brain.

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In a recent study published in the journal Cell, researchers describe recent advancements in breast cancer research and how these findings have improved the precise diagnosis of tumor subtypes and contributed to the discovery of novel drug targets for future therapeutics.

Study: Deciphering breast cancer: from biology to the clinic. Image Credit: ORION PRODUCTION / Shutterstock.com