Summary: A new method that targets the astrocytes surrounding glioblastoma brain cancer eradicates tumor cells and extends lifespan in animal models.
Source: Tel Aviv University.
A groundbreaking study at Tel Aviv University effectively eradicated glioblastoma, a highly lethal type of brain cancer.
Starting Monday, drive-thru customers at two Panera Bread locations in upstate New York will have their orders taken by a computer in a test of artificial intelligence technology’s accuracy and ability to decrease service times.
The sandwich chain is the latest restaurant company to invest in potential improvements to the drive-thru experience. A surge in drive-thru ordering during the Covid pandemic led to long lines of cars wrapped around restaurants, pushing chains to focus on speed of service and order accuracy.
For example, McDonald’s has also been working to automate its drive-thru lane, announcing a partnership last year with IBM to work toward that goal. Yum Brands’ Taco Bell and Restaurant Brands International’s Burger King have been building double drive-thru lanes at some locations to allow customers to pick up their digital orders more quickly. Fast-casual chains like Shake Shack and Sweetgreen that once balked at drive-thru lanes have been adding them.
Basically the United States has alerts for the west Nile as it seems to be spreading across many states.
As temperatures warm, US health officials are braced for rising rates of West Nile virus, a disease transmitted by mosquitoes that can cause meningitis, paralysis, and death.
Oklahoma reported its first West Nile death of the year on Thursday, in a resident who had been hospitalized with the illness.
As space travel for recreational purposes is becoming a very real possibility, there could come a time when we are travelling to other planets for holidays, or perhaps even to live. Commercial space company Blue Origin has already started sending paying customers on sub-orbital flights. And Elon Musk hopes to start a base on Mars with his firm SpaceX.
This means we need to start thinking about what it will be like to live in space – but also what will happen if someone dies there.
After death here on Earth the human body progresses through a number of stages of decomposition. These were described as early as 1,247 in Song Ci’s The Washing Away of Wrongs, essentially the first forensic science handbook.
Scientists will soon begin a clinical trial for a new liver disease treatment. The experimental treatment will hopefully help treat end-stage liver disease and reduce liver transplants. To do this, it will harness the natural regenerative power of the liver by growing an entirely new liver within the patient. It won’t just rely on one new liver, either. Instead, patients will grow multiple tiny livers in their bodies.
The process, which has shown success in mice, pigs, and dogs, involves injecting healthy liver cells into the patient’s lymph nodes. The cells then multiply inside the patient’s body, growing into tiny functioning versions of the larger organ. It’s an intriguing treatment for liver disease, and so far, it has improved liver function in animals that have received the treatment.
Researchers from the University of California of Berkeley transfused the blood of older mice into younger mice! This caused accelerated aging: Abstract in the youtube description.
A team from the University of Dundee has designed a molecule that eliminates a Parkinson’s disease-causing protein.
An unusual protein structure known as a “rippled beta sheet,” first predicted in 1953, has now been created in the laboratory and characterized in detail using X-ray crystallography.
The new findings, published in July in Chemical Science, may enable the rational design of unique materials based on the rippled sheet architecture.
“Our study establishes the rippled beta sheet layer configuration as a motif with general features and opens the road to structure-based design of unique molecular architectures, with potential for materials development and biomedical applications,” said Jevgenij Raskatov, associate professor of chemistry and biochemistry at UC Santa Cruz and corresponding author of the paper.
The skin is one of the largest and most accessible organs in the human body, but penetrating its deep layers for medicinal and cosmetic treatments still eludes science.
Although there are some remedies—such as nicotine patches to stop smoking—administered through the skin, this method of treatment is rare since the particles that penetrate must be no larger than 100 nanometers. Creating effective tools using such tiny particles is a great challenge. Because the particles are so small and difficult to see, it is equally challenging to determine their exact location inside the body—information necessary to ensure that they reach intended target tissue. Today such information is obtained through invasive, often painful, biopsies.
A novel approach, developed by researchers at Bar-Ilan University in Israel, provides an innovative solution to overcoming both of these challenges. Combining techniques in nanotechnology and optics, they produced tiny (nanometric) diamond particles so small that they are capable of penetrating skin to deliver medicinal and cosmetic remedies. In addition, they created a safe, laser-based optical method that quantifies nanodiamond penetration into the various layers of the skin and determines their location and concentration within body tissue in a non-invasive manner—eliminating the need for a biopsy.
A multidisciplinary team of Indiana University researchers have discovered that the motion of chromatin, the material that DNA is made of, can help facilitate effective repair of DNA damage in the human nucleus—a finding that could lead to improved cancer diagnosis and treatment. Their findings were recently published in the Proceedings of the National Academy of Sciences.
DNA damage happens naturally in human body and most of the damage can be repaired by the cell itself. However, unsuccessful repair could lead to cancer.
“DNA in the nucleus is always moving, not static. The motion of its high-order complex, chromatin, has a direct role in influencing DNA repair,” said Jing Liu, an assistant professor of physics in the School of Science at IUPUI. “In yeast, past research shows that DNA damage promotes chromatin motion, and the high mobility of it also facilitates the DNA repair. However, in human cells this relationship is more complicated.”
