Lifeboat Foundation

June 29 (Reuters) — Germany’s BioNTech (22UAy. DE), Pfizer’s (PFE.N) partner in COVID-19 vaccines, said the two companies would start tests on humans of next-generation shots that protect against a wide variety of coronaviruses in the second half of the year.

Their experimental work on shots that go beyond the current approach include T-cell-enhancing shots, designed to primarily protect against severe disease if the virus becomes more dangerous, and pan-coronavirus shots that protect against the broader family of viruses and its mutations.

In presentation slides posted on BioNTech’s website for its investor day, the German biotech firm said its aim was to “provide durable variant protection”.

Text-to-image generation is the hot algorithmic process right now, with OpenAI’s Craiyon (formerly DALL-E mini) and Google’s Imagen AIs unleashing tidal waves of wonderfully weird procedurally generated art synthesized from human and computer imaginations. On Tuesday, Meta revealed that it too has developed an AI image generation engine, one that it hopes will help to build immersive worlds in the Metaverse and create high digital art.

A lot of work into creating an image based on just the phrase, “there’s a horse in the hospital,” when using a generation AI. First the phrase itself is fed through a transformer model, a neural network that parses the words of the sentence and develops a contextual understanding of their relationship to one another. Once it gets the gist of what the user is describing, the AI will synthesize a new image using a set of GANs (generative adversarial networks).

Continue reading “Meta’s ‘Make-A-Scene’ AI blends human and computer imagination into algorithmic art” »

Patients undergo interventions to achieve a ‘normal’ brain temperature; a parameter that remains undefined for humans. The profound sensitivity of neuronal function to temperature implies the brain should be isothermal, but observations from patients and non-human primates suggest significant spatiotemporal variation. We aimed to determine the clinical relevance of brain temperature in patients by establishing how much it varies in healthy adults.

We retrospectively screened data for all patients recruited to the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) High Resolution Intensive Care Unit Sub-Study. Only patients with direct brain temperature measurements and without targeted temperature management were included. To interpret patient analyses, we prospectively recruited 40 healthy adults (20 males, 20 females, 20–40 years) for brain thermometry using magnetic resonance spectroscopy. Participants were scanned in the morning, afternoon, and late evening of a single day.

In patients (n = 114), brain temperature ranged from 32.6 to 42.3°C and mean brain temperature (38.5 ± 0.8°C) exceeded body temperature (37.5 ± 0.5°C, P 0.0001). Of 100 patients eligible for brain temperature rhythm analysis, 25 displayed a daily rhythm, and the brain temperature range decreased in older patients (P = 0.018). In healthy participants, brain temperature ranged from 36.1 to 40.9°C; mean brain temperature (38.5 ± 0.4°C) exceeded oral temperature (36.0 ± 0.5°C) and was 0.36°C higher in luteal females relative to follicular females and males (P = 0.0006 and P 0.0001, respectively). Temperature increased with age, most notably in deep brain regions (0.6°C over 20 years, P = 0.0002), and varied spatially by 2.41 ± 0.46°C with highest temperatures in the thalamus. Brain temperature varied by time of day, especially in deep regions (0.86°C, P = 0.0001), and was lowest at night. From the healthy data we built HEATWAVE—a 4D map of human brain temperature.

A new computer algorithm developed by the University of Toronto’s Parham Aarabi can store and recall information strategically—just like our brains.

The associate professor in the Edward S. Rogers Sr. department of electrical and computer engineering, in the Faculty of Applied Science & Engineering, has also created an experimental tool that leverages the new algorithm to help people with memory loss.

“Most people think of AI as more robot than human,” says Aarabi, whose framework is explored in a paper being presented this week at the IEEE Engineering in Medicine and Biology Society Conference in Glasgow. “I think that needs to change.”

INDIANAPOLIS (WISH) — It’s a question that’s puzzled doctors for decades: Why does cancer spread to where it spreads? Well, scientists may finally have an answer. Researchers at the University of…

The money will go to the Gates Foundation.

Microsoft founder Bill Gates revealed that he will give away his wealth for various reasons ranging from climate adaptation to pandemic prevention. This will eventually cross his name off on the world’s richest people list.

With his wife, Gates started the Bill and Melinda Gates Foundation (BMGF) in 2000 to fight disease, poverty, and inequity around the world\.

Continue reading “Bill Gates to erase himself from the billionaires list, donating $20 billion of his wealth” »

Reimagining Nuclear Medicine — Dr. Stephen Moran, Ph.D., Global Program Head, Neuroendocrine Tumors & Other Radiosensitive Cancers, Advanced Accelerator Applications, Novartis

Dr. Stephen Moran, Ph.D., is Global Program Head, Neuroendocrine Tumors & Other Radiosensitive Cancers, for Advanced Accelerator Applications (AAA — https://www.adacap.com/), a Novartis company and also a member of the Oncology Development Unit Leadership Team at Novartis.

Continue reading “Dr. Stephen Moran, PhD — Reimagining Nuclear Medicine — Advanced Accelerator Applications, Novartis” »

After a US Supreme Court draft decision on Roe v. Wade was leaked in May, Dr. Joshua Trebach noticed a disturbing turn in the online conversation around abortion.

“I started seeing things on social media, things like TikTok, Twitter, Facebook, Instagram, people saying ‘oh, if Roe v. Wade does get overturned, here are some secret, sneaky ways that you can drink some tea and have an abortion,’” Trebach said.

Now that Roe v. Wade has been overturned and some states are putting strict limits on abortions, there’s widespread confusion about whether the procedures are available and to whom. Physicians and poison control officials say they’re worried that people seeking abortions will turn to ineffective and dangerous methods shared online, potentially delaying or preventing safe, proven abortion care.

Researchers at Cornell University have come up with a novel biomaterial that can be used to create artificial skin capable of mimicking the behavior of natural human tissues.

Thanks to its unique composition, made up of collagen mixed with a ‘zwitterionic’ hydrogel, the team’s biohybrid composite is said to be soft and biocompatible, but flexible enough to withstand continued distortion. While the scientists’ R&D project remains ongoing, they say their bio-ink could one day be used as a basis for 3D printing scaffolds from patients’ cells, which effectively heal wounds in-situ.

“Ultimately, we want to create something for regenerative medicine purposes, such as a piece of scaffold that can withstand some initial loads until the tissue fully regenerates,” said Nikolaos Bouklas, one of the study’s co-lead authors. “With this material, you could 3D print a porous scaffold with cells that could eventually create the actual tissue around the scaffold.”