Lifeboat Foundation

The performance of numerous cutting-edge technologies, from lithium-ion batteries to the next wave of superconductors, hinges on a physical characteristic called intercalation. Predicting which intercalated materials will be stable poses a significant challenge, leading to extensive trial-and-error experimentation in the development of new products.

Now, in a study recently published in ACS Physical Chemistry Au, researchers from the Institute of Industrial Science, The University of Tokyo, and collaborating partners have devised a straightforward equation that correctly predicts the stability of intercalated materials. The systematic design guidelines enabled by this work will speed up the development of upcoming high-performance electronics and energy-storage devices.

USA: Using an electronic health record (EHR)-based algorithm plus practice facilitators embedded in primary care clinics did not reduce hospitalization at one year, according to a pragmatic trial involving patients with the triad of chronic kidney disease, hypertension, and type 2 diabetes.

“The hospitalization rate of patients in the intervention group at one year was about the same as that with usual care (20.7% vs 21.1%),” the researchers reported in the ICD-Pieces study published in the New England Journal of Medicine.

Patients with chronic kidney disease (CKD), type 2 diabetes (T2D), and hypertension (the kidney-dysfunction triad) are at high risk for multiple complications, end-stage kidney disease, and premature death. Despite the availability of effective therapies for these patients, there is a lack of results of large-scale trials examining the implementation of guideline-directed therapy to reduce death and complications risk in this population.

A theory of consciousness should capture its phenomenology, characterize its ontological status and extent, explain its causal structure and genesis, and describe its function. Here, I advance the notion that consciousness is best understood as an operator, in the sense of a physically implemented transition function that is acting on a representational substrate and controls its temporal evolution, and as such has no identity as an object or thing, but (like software running on a digital computer) it can be characterized as a law. Starting from the observation that biological information processing in multicellular substrates is based on self organization, I explore the conjecture that the functionality of consciousness represents the simplest algorithm that is discoverable by such substrates, and can impose function approximation via increasing representational coherence. I describe some properties of this operator, both with the goal of recovering the phenomenology of consciousness, and to get closer to a specification that would allow recreating it in computational simulations.

In science fiction, holograms are used for anything from basic communications to advanced military weaponry. In the real world, 3D holographic displays have yet to break through to everyday products and devices. That’s because creating holograms that look real and have significant fidelity requires laser emitters or other advanced pieces of optical equipment. This situation has stymied commercial development, as these components are complex and expensive.

More recently, research scientists were able to create realistic 3D holographic images without lasers by using a white chip-on-board light-emitting diode. Unfortunately, that method required two spatial light modulators to control the wave fronts of the emitted light, adding a prohibitive amount of complexity and cost.

Now, those same scientists say they have created a simpler, more cost-effective way to create realistic-looking 3D holographic displays using only one spatial light modulator and new software algorithms. The result is a simpler and cheaper method for creating holograms that an everyday technology like a smartphone screen can emit.

Shared with Dropbox.

In recent years, artificial intelligence technologies, especially machine learning algorithms, have made great strides. These technologies have enabled unprecedented efficiency in tasks such as image recognition, natural language generation and processing, and object detection, but such outstanding functionality requires substantial computational power as a foundation.

Combinatorial optimization problems (COPs) have applications in many different fields such as logistics, supply chain management, machine learning, material design and drug discovery, among others, for finding the optimal solution to complex problems. These problems are usually very computationally intensive using classical computers and thus solving COPs using quantum computers has attracted significant attention from both academia and industry.

Working memory (WM) is a kind of advanced cognitive function, which requires the participation and cooperation of multiple brain regions. Hippocampus and prefrontal cortex are the main responsible brain regions for WM. Exploring information coordination between hippocampus and prefrontal cortex during WM is a frontier problem in cognitive neuroscience. In this paper, an advanced information theory analysis based on bimodal neural electrical signals (local field potentials, LFPs and spikes) was employed to characterize the transcerebral information coordination across the two brain regions. Firstly, LFPs and spikes were recorded simultaneously from rat hippocampus and prefrontal cortex during the WM task by using multi-channel in vivo recording technique. Then, from the perspective of information theory, directional hippocampus-prefrontal cortex networks were constructed by using transfer entropy algorithm based on spectral coherence between LFPs and spikes. Finally, transcerebral coordination of bimodal information at the brain-network level was investigated during acquisition and performance of the WM task. The results show that the transfer entropy in directional hippocampus-prefrontal cortex networks is related to the acquisition and performance of WM. During the acquisition of WM, the information flow, local information transmission ability and information transmission efficiency of the directional hippocampus-prefrontal networks increase over learning days. During the performance of WM, the transfer entropy from the hippocampus to prefrontal cortex plays a leading role for bimodal information coordination across brain regions and hippocampus has a driving effect on prefrontal cortex. Furthermore, bimodal information coordination in the hippocampus → prefrontal cortex network could predict WM during the successful performance of WM.

Keywords: Bimodal neural electrical signals; Graph theory; Transcerebral information coordination; Transfer entropy; Working memory.

© The Author(s), under exclusive licence to Springer Nature B.V. 2022.

Advanced algorithms are now deciphering what once was the domain of pure human intellect.