Nice
A study providing new information about neuropathic pain afflicting some 90 percent of cancer patients who have had nerve damage caused by tumors, surgery, chemotherapy or radiation indicates gene therapy as a possible treatment.
The study in rats showed transfer of a gene known as KCC2 into the spinal canal restored chloride levels gone awry after nerve injury. Results from the research at The University of Texas MD Anderson Cancer Center, were published in the May 5 online issue of Cell Reports.
The results also could have implications for treatment of chronic pain due to diabetic neuropathy and spinal cord injury since neuropathic pain caused by these conditions is associated with reduced KCC2 activity.
Read more
Comments are closed.