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Nov 3, 2023

Nanoparticles deliver treatment directly to tumors of deadly brain cancer

Posted by in categories: biotech/medical, nanotechnology, neuroscience

Using nanoparticles administered directly into the cerebrospinal fluid (CSF), a research team has developed a treatment that may overcome significant challenges in treating a particularly deadly brain cancer.

The researchers, led by professors Mark Saltzman and Ranjit Bindra, administered to mice with medulloblastoma a treatment that features specially designed drug-carrying nanoparticles. The study, published in Science Translational Medicine, showed that mice who received this treatment lived significantly longer than mice in the control group.

Medulloblastoma, a that predominantly affects children, often begins with a tumor deep inside the . The cancer is prone to spread along two protective membranes known as the leptomeninges throughout the , particularly the surface of the brain and the CSF.

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