Blocking how cancer cells acquire and use energy, or their metabolism, as a treatment has been challenging, Dr. Lyssiotis explained. But a better understanding of how cancer cells adapt their metabolism in the often oxygen-and nutrient-deprived environments in which they exist, he said, may open other avenues for attacking them.
Identifying alternative sources of energy for cancer cells
Pancreatic cancer is one of the leading causes of death from cancer. Not only does its stark microenvironment thwart the entry of drugs designed to kill tumors, but numerous studies have shown that other residents in and around the tumors create an ecosystem that help the tumors thrive.
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