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Dec 14, 2023

Scientists Uncover Mechanism for Treating Dangerous Liver Condition

Posted by in category: biotech/medical

A recent study conducted by Oregon State University has unveiled new insights into how certain polyunsaturated fatty acids, specifically omega 3, combat a severe liver condition. This discovery paves the way for novel drug research for nonalcoholic steatohepatitis (NASH), a disease currently without any FDA-approved treatments.

Scientists led by Oregon State’s Natalia Shulzhenko, Andrey Morgun and Donald Jump used a technique known as multi-omic network analysis to identify the mechanism through which dietary omega 3 supplements alleviated nonalcoholic steatohepatitis, usually abbreviated to NASH.

The mechanism involves betacellulin, a protein growth factor that plays multiple positive roles in the body but also contributes to liver fibrosis, or scarring, and the progression to cirrhosis and liver cancer.

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