How Obesity Dismantles the Powerhouse of the Cell: A new UC San Diego School of Medicine study in Nature Portfolio (Metabolism) sheds light on how obesity affects our mitochondria, the all-important energy-producing structures of our cells.
UC San Diego researchers found that when mice were fed a high-fat diet, mitochondria within their fat cells broke apart and were less able to burn fat, leading to weight gain. They also found they could reverse the effect by targeting a single gene, suggesting a new treatment strategy for obesity.
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