Aug 30, 2020
There’s Now a Swifter Way to 3D-Print Organs
Posted by Shailesh Prasad in categories: 3D printing, biotech/medical
This groundbreaking technique might be used to replace human organs with lab-grown versions 😮.
This groundbreaking technique might be used to replace human organs with lab-grown versions 😮.
Using nothing but light and bioink, scientists were able to directly print a human ear-like structure under the skin of mice. The team used a healthy ear as a template and 3D printed a mirror image of that ear—tissue layer by tissue layer—directly onto the back of a mouse.
All without a single surgical cut.
If you’re thinking that’s super creepy, yeah…I’m with you. As a proof-of-concept, however, the team shows that it’s possible to build or rebuild tissue layers, even those as intricate as an ear, without requiring surgical implant. This means that it could one day be possible to fix an ear or other surface tissue defects—either genetic or from injuries—directly at the injury site by basically waving a sophisticated light wand.
The embryos, which were not allowed to develop past 28 days of age, move researchers a small step closer to perhaps growing human organs for medical transplant.
Every hour, six people in the United States are added to the national waiting list for organ transplants—and each day, 22 people on the list die waiting. In the U.S. alone, more than a hundred thousand people need heart transplants each year, but only about 2,000 receive one.
In response, researchers are working to artificially expand the organ supply. Some are trying to 3D print organs in the lab. Others are working on artificial, mechanical organs. And some are making chimeras—hybrids of two different species—in the hopes of growing human organs in pigs or sheep.
In just two years a robotic device that prints a patient’s own skin cells directly onto a burn or wound could have its first-in-human clinical trials. The 3D bioprinting system for intraoperative skin regeneration developed by Australian biotech start-up Inventia Life Science has gained new momentum thanks to major investments from the Australian government and two powerful new partners, world-renowned burns expert Fiona Wood and leading bioprinting researcher Gordon Wallace.
Codenamed Ligō from the Latin “to bind”, the system is expected to revolutionize wound repairs by delivering multiple cell types and biomaterials rapidly and precisely, creating a new layer of skin where it has been damaged. The novel system is slated to replace current wound healing methods that simply attempt to repair the skin, and is being developed by Inventia Skin, a subsidiary of Inventia Life Science.
“When we started Inventia Life Science, our vision was to create a technology platform with the potential to bring enormous benefit to human health. We are pleased to see how fast that vision is progressing alongside our fantastic collaborators. This Federal Government support will definitely help us accelerate even faster,” said Dr. Julio Ribeiro, CEO, and co-founder of Inventia.
Episode 13; please check out this candid interview with Lowell Observatory astronomer Gerard van Belle on why we need interferometry in space. Many thanks!
Lowell Observatory astronomer Gerard van Belle, Chief Scientist at the Navy Precision Optical Interferometer (NPOI) in Flagstaff. Arizona talks about the possibility of arrays of space telescopes that are 3D printed after launch. We also discuss the history of optical interferometry; why such interlinked telescopes are the key to America’s future in astronomy and why Arizona skies remain as vital today as they were a century ago.
Elon Musk’s Neuralink will likely show off its design for a brain-computer interface Friday evening. The concept it unveiled last summer involves surgically implanting it into the brain to detect the activity of neurons. The US military also wants to develop a brain-computer interface, as we explain in this story from October. But here’s the kicker: no surgery required—and the device could be put on and taken off like a helmet or headband.
In August, three graduate students at Carnegie Mellon University were crammed together in a small, windowless basement lab, using a jury-rigged 3D printer frame to zap a slice of mouse brain with electricity.
The brain fragment, cut from the hippocampus, looked like a piece of thinly sliced garlic. It rested on a platform near the center of the contraption. A narrow tube bathed the slice in a solution of salt, glucose, and amino acids. This kept it alive, after a fashion: neurons in the slice continued to fire, allowing the experimenters to gather data. An array of electrodes beneath the slice delivered the electric zaps, while a syringe-like metal probe measured how the neurons reacted. Bright LED lamps illuminated the dish. The setup, to use the lab members’ lingo, was kind of hacky.
Continue reading “The US military is trying to read minds” »
Keyed locks are relatively easy to pick if you’ve spent enough time mastering the skill. But researchers at the National University of Singapore have just made it even easier. If you can use a smartphone to record a sound, you can capture all the information you need to create a working duplicate of a key.
The newfound vulnerability – although it’s more a case of modern technology compromising an outdated technology – was discovered by cyberphysical systems researcher Soundarya Ramesh and a team at the National University of Singapore. The attack, called SpiKey, works on what are known as pin tumbler locks that are opened using a key with a unique ridge pattern on its edge. As the key slides into the lock, the ridges push six metal spring-backed pins to different heights which, when all are properly aligned, allow a tumbler to turn and a lock to be opened. They’re one of the most common types of locks out there, used in everything from doors to padlocks, which makes this attack especially concerning.
To open a pin tumbler lock without the key, a locksmith (or lock pick) uses a specialised set of tools to manually adjust the height of each pin, one by one, until they figure out the unique arrangement needed for the tumbler to turn. The SpiKey technique is magnitudes easier, and requires little to no special skills, aside from the ins and outs of operating a 3D printer.
U.S. Army researchers have teamed with Texas A&M University to create a new polymer material that can shape-shift and autonomously heal itself as part of a research effort to improve future unmanned air and robotic vehicles.
In early research, the first-of-its-kind, 3D-printable epoxy-based material can respond to stimuli, and researchers hope it will one day have embedded intelligence allowing it to adapt to its environment without any external control, according to a news release from Army Combat Capabilities Development Command’s (CCDC) Army Research Laboratory.
Read Next: Mortar Shells Strike Kabul as Afghans Mark Independence Day.
Unlike a traditional rocket engine, which consists of individually designed parts that are combined together the AI designed rocket engine was 3D printed as one continuous piece. This includes both the combustion chamber where fuel and oxidiser is burned and the surface channels, through which the fuel is circulated to cool the chamber and keep it from overheating.
“In a rocket, the cooling channels are generally welded onto the combustion chamber, which through wear and tear can cause errors and explosions,” explained Hyperganic’s design director Duy-Anh Pham.
For the past number of years I’ve been taking about the rise of so called Creative Machines, Artificial Intelligence (AI) based “innovation” machines, that can design and innovate things for themselves without any human intervention – things such as aircraft parts, chairs, fashion lines, interplanetary rovers, self-evolving robots, and Under Armour trainers. And now those same creative machines have made yet another leap, and again it’s another first for the space industry, after German software company Hyperganic announced they’d developed a 3D printed rocket engine prototype, which was completely designed by AI.
Continue reading “An AI just designed then 3D printed a completely new form of rocket engine” »
In Korea, scientists are turning to better ways for improving our screen time, and this means 3D printing something most of us know little about: quantum dots. Focusing on refining the wonders of virtual reality and other electronic displays even further, researchers from the Nano Hybrid Technology Research Center of Korea Electrotechnology Research Institute (KERI), a government-funded research institute under National Research Council of Science & Technology (NST) of the Ministry of Science and ICT (MSIT), have created nanophotonic 3D printing technology for screens. Meant to be used with virtual reality, as well as TVs, smartphones, and wearables, high resolution is achieved due to a 3D layout expanding the density and quality of the pixels.
Led by Dr. Jaeyeon Pyo and Dr. Seung Kwon Seol, the team has published the results of their research and development in “3D-Printed Quantum Dot Nanopixels.” While pixels are produced to represent data in many electronics, conventionally they are created with 2D patterning. To overcome limitations in brightness and resolution, the scientists elevated this previously strained technology to the next level with 3D printed quantum dots to be contained within polymer nanowires.