Lifeboat Foundation

Have you ever looked back on a moment and wondered if you made the right choice? Professor Robert Sapolsky has, but he believes that there was no actual choice at that moment. Professor Sapolsky has staked out an extreme stance in the field: we are nothing more than the sum of our biology, over which we had no control, and its interactions with the environment, over which we also had no control. Explore what it looks like to reject the notion of free will and how doing so can be liberating rather than paralyzing and despairing.

About the Speaker.
Professor Robert Sapolsky is the John A. and Cynthia Fry Gunn Professor and a professor of biology, of neurology, and of neurosurgery. Over the past thirty years, he has divided his time between the lab, where he studies how stress hormones can damage the brain, and in East Africa, where he studies the impact of chronic stress on the health of baboons.

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A QUT-led team of international researchers has made a breakthrough in the development of a type of battery that is much safer and cheaper than the batteries currently charging our smart devices.

The research, published in the Journal of the American Chemical Society, has demonstrated a way of improving the voltage of aqueous zinc-ion batteries, which are a type of rechargeable battery which have a water-based electrolyte.

QUT researchers involved in the study are Professor Ziqi Sun, Associate Professor Dongchen Qi, and Fan Zhang from the School of Chemistry and Physics, Professor Ting Liao and Professor Cheng Yan from the School of Mechanical, Medical and Process Engineering and Dr. Aaron Micallef from the Central Analytical Research Facility.

Bacterial superorganisms must evolve defenses to fight off infections, and microbiologists found that they use a weapons cache coincidentally similar to that of the human immune system.

Feb. 1, 2024 – A common condition called polycystic ovary syndrome that causes irregular menstrual cycles has been linked to signs of early cognitive decline.

Known as PCOS, the condition may affect more than 1 in 10 women, and is among the most common causes of infertility. In addition to ovulation problems, PCOS can cause excess hair growth on the face and the other parts of the body, as well as abnormal growths on the ovaries. Women with PCOS are at a particularly heightened risk of getting type 2 diabetes, as well as other serious health conditions like heart disease, high blood pressure, cholesterol problems, and sleep apnea, particularly if the women are overweight.

This latest study looked for possible links between PCOS and brain health in women once they were in their late 40s or older.

Researchers at Aalto University were looking for better ways to instruct dance choreography in virtual reality. The new WAVE technique they developed will be presented in May at the CHI conference for human-computer interaction research.

Previous techniques have largely relied on pre-rehearsal and simplification.

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The following is a summary of “Emerging therapeutic frontiers in cancer: insights into posttranslational modifications of PD-1/PD-L1 and regulatory pathways,” published in the April 2024 issue of Hematology by Wang et al.

The intricate interplay between programmed cell death ligand 1 (PD-L1), expressed on the surface of tumor cells, and programmed cell death 1 (PD-1), expressed on T cells, constitutes a pivotal mechanism fostering immune evasion by tumor cells through the thwarting of effective tumor antigen-specific T cell activation. The advent of PD-1/PD-L1 blockade has emerged as a transformative strategy in combating tumor immune evasion, garnering substantial interest within the oncology landscape. Clinical investigations have underscored the remarkable efficacy and safety profile of PD-1/PD-L1 blocking antibodies across a spectrum of malignancies, offering a beacon of hope for patients.

Nonetheless, the therapeutic landscape of anti-PD-1/PD-L1 interventions is fraught with challenges, including limited indications and the emergence of drug resistance, necessitating a nuanced approach to therapeutic intervention. Accordingly, unraveling additional regulatory pathways and molecular players associated with PD-1/PD-L1 signaling assumes paramount importance, alongside the strategic implementation of combinational therapeutic modalities, to address the multifaceted dynamics of tumor immune evasion.

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A research team led by the late Professor Liang Haojun from the Hefei National Laboratory for Physical Sciences at the Microscale of University of Science and Technology of China (USTC) has developed a facile enthalpy-mediated strategy to precisely control the replication and catalytic assembly of DNA-functionalized colloids in a time-dependent manner, facilitating the creation of large-scale ordered nanomaterials. The study was published in Angewandte Chemie International Edition.

The replication of information is a fundamental characteristic of nature, with nucleic acids playing a crucial role in biological systems. However, creating synthetic systems that can produce large-scale, three-dimensionally ordered nanomaterials using self-replicating nanostructures has remained a formidable challenge.

Existing artificial self-replicating systems often fall short in programmable assembly into sophisticated nanostructures, limiting their potential functions and applications.

Angela Ting, Ph.D., was intrigued by the field of epigenetics as soon as she was introduced to it in college. Now, she runs a research lab that explores how epigenetics plays a role in the development of cancer. She wants to use that knowledge to better treat patients with certain types of cancer.