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Archive for the ‘biotech/medical’ category: Page 1915

Aug 13, 2019

Asia’s affluent boomers are making aging aspirational

Posted by in categories: biotech/medical, life extension

Medical tourism has some overlap with the anti-aging market, but the way these consumers are thinking about their own longevity will likely bring up new questions for providers. Middle-aged Asian consumers don’t want to buy youth, they want to buy things that make them appreciate where they are right now.


Middle-aged Asian consumers are giving the anti-aging market a run for its money.

Aug 12, 2019

Police can now use millions more people’s DNA to find criminals

Posted by in categories: biotech/medical, genetics

By Chelsea Whyte

Policing power may be about to get much stronger, thanks to another advance in genetic analysis. A new technique can link the patchy, limited DNA information held in forensic databases to the rich DNA libraries held by family tree-building websites, raising further questions about genetic privacy.

Earlier this year, an ancestry database used by people looking to trace their family history was used to identify the suspected Golden State Killer, a serial killer active in California decades ago. Since his arrest in April, genealogy databases – which allow consumers to upload their DNA sequences – have been used to crack several other cold cases.

Aug 12, 2019

Boston Strangler Case Solved After 50 Years

Posted by in categories: biotech/medical, law enforcement

A water bottle recovered from a construction site where Tim DeSalvo – whose uncle Albert DeSalvo had confessed to being the internationally notorious Boston Strangler – gave police the DNA evidence they needed to bring closure to a case that has been a mystery for nearly 50 years, murders for which no one has ever been charged.

“This is really a story of relentlessness,’’ Boston Police Commissioner Ed Davis explained today as Massachusetts top law enforcement officials revealed that DNA preserved from the body of the Boston Strangler’s last victim—raped and murdered in 1964—can now be linked with ”99.9 percent certainty” to the late Albert DeSalvo.

”This is good evidence. This is strong evidence. This is reliable evidence,’’ Suffolk County District Attorney Dan Conley said of the new DNA result. ”But there can be no doubt.”

Aug 12, 2019

Deadly Legionnaires’ outbreak at Atlanta hotel a “nationwide problem,” attorney says

Posted by in categories: biotech/medical, health

A widespread outbreak of Legionnaires’ disease has killed one person and sickened possibly dozens of others who were all guests at the Sheraton Atlanta Hotel. The hotel evacuated all its guests on July 15 and remains closed as of press time.

Public health officials say a dozen guests had tested positive for Legionnaires’, a bacteria that can cause a severe form of pneumonia. But according to the attorney filing a lawsuit Monday, hundreds more may have been exposed.

By the time guests were evacuated in mid-July, 49-year-old Cameo Garrett was already dead. An autopsy showed she had coronary issues and Legionnaires’ disease. Garrett went to a conference at the Sheraton a week before she died – just like Germany Greer who said he became so sick at one point he didn’t even know his own name.

Aug 12, 2019

Incredible Stanford study discovers thousands of novel proteins produced by human microbiome

Posted by in categories: biotech/medical, futurism

A remarkable new study from scientists at Stanford University has revealed thousands of previously undiscovered small proteins produced by bacteria in the human microbiome. Almost all of these newly described proteins serve unknown functions in the human body and the researchers suggest their discovery opens up a new frontier for future therapeutic drug development.

Aug 12, 2019

Yale scientists zero in on atomic driver of tumor formation

Posted by in category: biotech/medical

Growing evidence suggests that certain types of bacteria are capable of causing colorectal cancers, indicating that a sub-set of these cancers could be the result of infectious disease.

But understanding how bacteria interact in the human gut – our microbiome — has been challenging because of the complex microbial mixture of “good” and “bad” bacteria.

Over a decade ago, French scientists discovered a pathway in certain strains of E. coli, a bacterium normally found in 90% of humans, that is “genotoxic” – toxic to DNA – causing tumor formation and colorectal cancer in mice.

Aug 12, 2019

To Find The Next Antibiotic, Scientists Give Old Drugs A New Purpose

Posted by in categories: biotech/medical, health

Fighting Antibiotic Resistance By Repurposing Old Drugs : Shots — Health News Scientists discovered that a medication used to treat parasites in horses can fight deadly staph infections. It’s a promising new approach to solving the problem of antibiotic resistance.

Aug 12, 2019

Multiplexed genome engineering

Posted by in categories: bioengineering, biotech/medical, genetics

The ability to modify multiple genetic elements simultaneously would help to elucidate and control the gene interactions and networks underlying complex cellular functions. However, current genome engineering technologies are limited in both the number and the type of perturbations that can be performed simultaneously. Here, we demonstrate that both Cas12a and a clustered regularly interspaced short palindromic repeat (CRISPR) array can be encoded in a single transcript by adding a stabilizer tertiary RNA structure. By leveraging this system, we illustrate constitutive, conditional, inducible, orthogonal and multiplexed genome engineering of endogenous targets using up to 25 individual CRISPR RNAs delivered on a single plasmid. Our method provides a powerful platform to investigate and orchestrate the sophisticated genetic programs underlying complex cell behaviors.

Aug 12, 2019

Superbug is evolving to thrive in guts of people with sugary diets, scientists warn

Posted by in category: biotech/medical

The sugar-rich Western diet is fueling a superbug which has evolved to thrive in hospitals, scientists have warned.

The gut-infecting bacterium Clostridium difficile (C.diff) is evolving into two separate species, with one group increasingly adapting to live in the guts of people with poor diets, while growing ever better at avoiding the harsh disinfectants used to clean wards.

More than 13,000 NHS patients each year are infected with C.diff, which can cause debilitating diarrhoea and leave sick people dangerously dehydrated.

Aug 12, 2019

FDA announces new policy framework for development of regenerative medicine products

Posted by in categories: biotech/medical, genetics, life extension, policy

Today the U.S. Food and Drug Administration announced a comprehensive policy framework for the development and oversight of regenerative medicine products, including novel cellular therapies.

The framework — outlined in a suite of four guidance documents — builds upon the FDA’s existing risk-based regulatory approach to more clearly describe what products are regulated as drugs, devices, and/or biological products. Further, two of the guidance documents propose an efficient, science-based process for helping to ensure the safety and effectiveness of these therapies, while supporting development in this area. The suite of guidance documents also defines a risk-based framework for how the FDA intends to focus its enforcement actions against those products that raise potential significant safety concerns. This modern framework is intended to balance the agency’s commitment to safety with mechanisms to drive further advances in regenerative medicine so innovators can bring new, effective therapies to patients as quickly and safely as possible. The policy also delivers on important provisions of the 21st Century Cures Act.

We’re at the beginning of a paradigm change in medicine with the promise of being able to facilitate regeneration of parts of the human body, where cells and tissues can be engineered to grow healthy, functional organs to replace diseased ones; new genes can be introduced into the body to combat disease; and adult stem cells can generate replacements for cells that are lost to injury or disease. This is no longer the stuff of science fiction. This is the practical promise of modern applications of regenerative medicine.