Archive for the ‘biotech/medical’ category: Page 2008
Apr 30, 2019
Deadly box jellyfish antidote discovered using CRISPR genome editing
Posted by Quinn Sena in category: biotech/medical
Researchers at the University of Sydney have discovered an antidote to the deadly sting delivered by the most venomous creature on earth—the Australian box jellyfish.
The Australian box jellyfish (Chironex fleckeri) has about 60 tentacles that can grow up to three metres long. Each tentacle has millions of microscopic hooks filled with venom.
Each box jellyfish carries enough venom to kill more than 60 humans.
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Apr 30, 2019
Scientists Plan to 3D Print Muscular Tissue on the Space Station
Posted by Klaus Baldauf in categories: 3D printing, biotech/medical, space travel
Apr 30, 2019
Finally, another effective drug for kids and teens with type 2 diabetes
Posted by Paul Battista in categories: biotech/medical, health
Results of a recently completed clinical trial of a potential drug to treat Type 2 diabetes in children were announced Sunday [April 28] at the Pediatric Academic Societies 2019 meeting in Baltimore, Md. The New England Journal of Medicine also published the findings. Study coauthor Jane Lynch, M.D., FAAP, professor of pediatrics at UT Health San Antonio, said the drug, liraglutide, in combination with an existing medication, metformin, showed robust effect in treating children studied in the Ellipse trial.
Currently only two drugs, metformin and insulin, are approved by the U.S. Food and Drug Administration for the treatment of Type 2 diabetes in children. By comparison, more than 30 drugs are approved to treat this form of diabetes in adults.
“We’ve not been able to get drugs approved for children beyond metformin and insulin,” Dr. Lynch said. “This adult diabetes medication was very effective in our trial of youth with Type 2 diabetes and was well tolerated. We urgently need other options for medical treatment of Type 2 diabetes in our youth under age 18. If approved, this drug would be a fantastic new option to complement oral metformin therapy as an alternative to insulin for our youth and adolescents with Type 2 diabetes.”
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Apr 30, 2019
DNA folds into a smart nanocapsule for drug delivery
Posted by Paul Battista in categories: biotech/medical, nanotechnology
Researchers from University of Jyväskylä and Aalto University in Finland have developed a customized DNA nanostructure that can perform a predefined task in human body-like conditions. To do so, the team built a capsule-like carrier that opens and closes according to the pH level of the surrounding solution. The nanocapsule can be loaded—or packed—with a variety of cargo, closed for delivery and opened again through a subtle pH increase.
Apr 30, 2019
The April Journal Club will be discussing the recent paper from the Salk Institute
Posted by Steve Hill in categories: biotech/medical, life extension
The findings, published in the journal Nature Medicine, showcase a novel CRISPR/Cas9 genome-editing therapy that can suppress the accelerated aging observed in mice with Hutchinson-Gilford progeria syndrome. This treatment provides an important insight into the molecular pathways involved in accelerated aging, as well as how to reduce toxic proteins via gene therapy. The researchers hope to translate this therapy to humans to potentially provide a cure for progeria as well as possibly slowing down the aging process to delay the onset of age-related diseases in everyone.
Link to paper: https://www.nature.com/articles/s41591-019-0343-4
Abstract.
Apr 30, 2019
Tony Oro: Stem cell therapies for incurable diseases
Posted by Paul Battista in category: biotech/medical
Apr 30, 2019
NMN Improves Cognitive Function in Aged Mice
Posted by Steve Hill in categories: biotech/medical, life extension, neuroscience
Researchers have tested nicotinamide mononucleotide on aged mice to see if it can help reverse age-related cognitive decline by improving blood flow in the brain.
The brain is a hungry organ
Healthy brain function relies on efficient cerebral blood flow (CBF) to wash away harmful waste products for disposal and supply the brain with an adequate supply of oxygen and sufficient nutrients.
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Apr 29, 2019
Doctors used a drone to deliver a vital kidney transplant in historic flight
Posted by Genevieve Klien in categories: biotech/medical, drones
https://youtube.com/watch?v=RNYCCbCpAlM
Drones might be a favorite toy among adults with significant disposable income, but they’ve also proven to be incredibly useful as tools, and sometimes life-saving ones at that. The latest example of this growing trend comes to us from the University of Maryland Medical Center, where a medical drone delivered a kidney that was subsequently successfully transplanted into a patient.
The delivery, which was documented in a brief YouTube video published by UMMC, is just a small first step in a larger effort to enhance the delivery systems used for vital items like organs and other medical materials.
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Apr 29, 2019
‘Earth-shattering’: Drone delivers kidney for transplant over Baltimore
Posted by Shailesh Prasad in categories: biotech/medical, drones, robotics/AI
https://youtube.com/watch?v=RNYCCbCpAlM
The drone delivery of a kidney recently used for an organ transplant in Baltimore is being characterized by the University of Maryland as a “pioneering breakthrough” advancement in human medicine and aviation technology.
“It’s huge. We knew from the very first time that we met with Dr. (Joseph) Scalea, and he suggested the idea of what he wanted to do — we knew it would be earth-shattering and life-changing, and it really has become that,” Matthew Scassero, director of the Unmanned Aircraft Systems Test Site at the University of Maryland, told WTOP.
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