Lifeboat Foundation

Scientists in the US may be out in front developing the next generation of Crispr-based genetic tools, but it’s China that’s pushing those techniques toward human therapies the fastest. Chinese researchers were the first to Crispr monkeys, and non-viable embryos, and to stick Crispr’d cells into a real live human. And now, a team of scientists in China have used a cutting-edge Crispr technique, known as base editing, to repair a disease-causing mutation in viable human embryos.

Published last week in the journal Molecular Therapy, and reported first by Stat, the study represents significant progress over previous attempts to remodel the DNA of human embryos. That’s in part because the editing worked so well, and in part because that editing took place in embryos created by a standard in-vitro fertilization technique.

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Research involving 1,000 scientists finds scores of genetic markers that identify people most likely to develop diseases.

Ian Sample, science correspondent.

Bacteria found in the human gut could save countless lives by transforming type A or type B blood into type O.

At a meeting of the American Chemical Society today, Steve Withers of the University of British Colombia presented new research suggesting enzymes found in gut bacteria could effectively strip antigens from the two most common blood types. If successful, the discovery would essentially make most types of blood accessible to those who need it, regardless of their blood type.

If you’ve read some of my latest articles, you might remember that I’ve been spending some time in my hometown. My quasi-holiday is not over yet, but my stay in my hometown pretty much is; I’m leaving in a few hours.

During my stay, I’ve told my girlfriend many times that wandering around my hometown feels like having someone else’s memories implanted in my head. I’ve never considered myself too attached to the place where I grew up, but after years of absence, I’ve become even less so. It’s like the place doesn’t have an effect on me anymore; it can’t really influence me. I know my way around it and I remember where landmarks and things are, but there’s little emotional connection left. It’s almost like being a tourist. Even my own room, which used to be pretty much my realm up until I was 18, now feels just like any regular room—in no small part because it has changed quite a bit since then. Given a few more years, I might lose all feelings for the place.

This shouldn’t be a surprise. Your feelings for places and people change and sometimes fade away altogether, over the years. This happens within currently normal lifetimes; what is going to happen if and when our lives last for centuries?

Healthy diet linked to healthy aging and longer telomeres, a new study on 5000 healthy adults. Relationship significant in women. … All four diets emphasize eating plenty of fruits, vegetables, whole grains and plant-based protein and limiting consumption of sugar, sodium and red and processed meat. Overall, the findings suggest that following these guidelines is associated with longer telomere length and reduces the risk of major chronic disease…”

Eating a diet that is rich in fruits, vegetables and whole grains and low in added sugar, sodium and processed meats could help promote healthy cellular aging in women, according to a new study published in the American Journal of Epidemiology.

“The key takeaway is that following a healthy diet can help us maintain healthy cells and avoid certain chronic diseases,” said lead author Cindy Leung, assistant professor of nutritional sciences at the University of Michigan School of Public Health. “Emphasis should be placed on improving the overall quality of your diet rather than emphasizing individual foods or nutrients.”

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A new study showed physical activity might lower cardiovascular disease risk by improving blood vessel function.

Adults in their early 60s, who spend less time sitting and more time engaged in light to vigorous physical activity, benefit with healthier levels of heart and vessel disease markers, according to new research in Journal of the American Heart Association, the Open Access Journal of the American Heart Association/American Stroke Association.

The results from increased physical activity were found to be particularly good among women.

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A new family of enzymes found in the human gut has been used to quickly turn type A blood into type O — which can be used for transfusions in anyone.

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Today we will be taking a look at a new paper that shows inhibiting TGFβ can boost liver regeneration.

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It’s an unfortunate fact of life that as we get older, our cells gradually lose the ability to heal themselves. Thankfully, at least one aspect of that might be treatable in the near future, if new work from Georgia Tech pans out. Researchers have developed a hydrogel that holds muscle stem cells, and by injecting this near the site of a muscle injury they can get to work repairing it. The team says the technique could be effective at treating injuries in the elderly and people with muscular dystrophy.