Biologist Daisy Robinton talks about engineering aging and the possibilities new technology offers.
Harvard University biologist Daisy Robinton reveals how science is helping us understand how and why we age.
Changes to gene activity that occur with age can be turned back, a new study shows.
A ‘living bandage’ made from stem cells, which could revolutionise the treatment and prognosis of a common sporting knee injury, has been trialled in humans for the first time by scientists at the Universities of Liverpool and Bristol.
Meniscal tears are suffered by over one million people a year in the US and Europe alone and are particularly common in contact sports like football and rugby. 90% or more of tears occur in the white zone of meniscus which lacks a blood supply, making them difficult to repair. Many professional sports players opt to have the torn tissue removed altogether, risking osteoarthritis in later life.
The Cell Bandage has been developed by spin-out company Azellon, and is designed to enable the meniscal tear to repair itself by encouraging cell growth in the affected tissue.
Continue reading “Stem cell ‘living bandage’ for knee injuries trialed in humans” »
Check out the LEAF interview with Synthetic Biology company CellAge who plan to use their technology to create aging biomarkers for the research community to use for free as well as new approaches to removing senescent cells.
CellAge are using synthetic biology to remove senescent cells that accumulate with age and contribute to disease. We took the time to interview them about their technology, treating age-related diseases and their plans for the future.
You can also check out their campaign on Lifespan.io:
Continue reading “CellAge – Synthetic biology meets senolytics” »
Progress with treating osteoporosis.
A team of scientists at the Children’s Medical Center Research Institute at UT Southwestern (CRI) discovered a new bone-forming growth factor, Osteolectin (Clec11a), which reverses osteoporosis in mice and has implications for regenerative medicine.
Although Osteolectin is known to be made by certain bone marrow and bone cells, CRI researchers are the first to show Osteolectin promotes the formation of new bone from skeletal stem cells in the bone marrow. The study, published in eLife, also found that deletion of Osteolectin in mice causes accelerated bone loss during adulthood and symptoms of osteoporosis, such as reduced bone strength and delayed fracture healing.
Dr. Aubrey de Grey on the case again in this amusing video.
Dr. Aubrey de Grey in a new video where people ask questions via Twitter. It is a bit tongue in cheek and sorry about the title but hopefully you will enjoy it,
Continue reading “Is it Possible to Defeat Death? SENS Research Over 9000!” »
An interesting but predictably hyped research study currently doing the rounds. Epigentic changes are one of the Hallmarks of Aging and this study reinforces their importance despite the usual media hype.
Graying hair, crow’s feet, an injury that’s taking longer to heal than when we were 20—faced with the unmistakable signs of aging, most of us have had a least one fantasy of turning back time. Now, scientists at the Salk Institute have found that intermittent expression of genes normally associated with an embryonic state can reverse the hallmarks of old age.
This approach, which not only prompted human skin cells in a dish to look and behave young again, also resulted in the rejuvenation of mice with a premature aging disease, countering signs of aging and increasing the animals’ lifespan by 30 percent. The early-stage work provides insight both into the cellular drivers of aging and possible therapeutic approaches for improving human health and longevity.
Continue reading “Cellular reprogramming reverses signs of aging” »
In September, a doctor named John Zhang announced that a baby, created via a complicated fertility treatment involving DNA contributions from three people, was successfully delivered the previous April. Now the U.K. has opened the way for more attempts at creating babies with three parents.
The fertility treatment involves sperm, an egg from the prospective mother, and an egg from a donor and has been used to help women who have mitochondrial issues with their eggs, replacing the nucleus DNA of those eggs with that of donor, either before or after fertilization. The embryo then carries the donor’s mitochondrial DNA, which amounts to less than 1% of the resulting child’s genes. CBS News reports that on Thursday, Britain’s fertility regulator, Human Fertilisation and Embryology Authority, approved the technique.
https://youtube.com/watch?v=JA8PRMacArU
We already know that excessive amounts of stress long term can cause certain individuals with certain predisposition cancer genetic mutations can cause cancer such as breast cancer. So, not surprise to see this.
In some situations, people who got hurt, replay the disturbing moment in their heads for many times and for many days. Every repetition you make usually causes more intense feelings making the situation worse.
Continue reading “Scientists Evidence: Negativity Literally Makes Cancer Grow Inside the Body” »
