Lifeboat Foundation

Several techniques currently are used to determine the pace of aging in animals and, to a lesser degree, in humans. However, the techniques used in humans lack accuracy, don’t assess aging in specific organs, are not widely available, and are expensive.

A multi-institutional research team measured the levels of nearly 5,000 human proteins in 5,676 people of all ages who were followed for as long as 15 years in five prospective longitudinal cohorts. Each measured protein was associated with specific organs, based on previous studies: adipose tissue, artery, brain, heart, immune tissue, intestine, kidney, liver, lung, muscle, or pancreas. Combinations of proteins indicated the pace of aging in each organ. Accelerated aging of one organ was found in nearly 20% of people, and accelerated aging of multiple organs was noted in ≈2%. Accelerated aging in a specific organ correlated with risk for developing disease in that organ. For example, people with accelerated heart aging (vs. those without it) had 250% higher risk for developing heart failure, and people with accelerated brain and vascular aging had nearly 60% higher risk for developing Alzheimer disease.

Various tools — from sequencing a person’s genome to measuring gene expression (e.g., the “methylome”) — are becoming available to predict a person’s risk for developing particular diseases. Will these predictions lead to interventions that lower risk? The jury is still out on that question.

A study done by Duke Health saw the procedure resulting in functioning valves and arteries that grow along with the young patient.

In a small group of veterans diagnosed with mild traumatic brain injury, treatment with a psychedelic drug, ibogaine was associated with improvements in daily function and mental health symptoms, a new study out of Stanford found.

“This could be one of the first treatments for traumatic brain injury,” said Dr. Nolan Williams, associate professor of psychiatry at Stanford, and principal study investigator. “I think it’s a moment of hope for veterans and folks with permanent neurological injury.”

The Federal Drug Administration classifies ibogaine as a Schedule I drug, citing “high abuse potential” and “no accepted medical use.” To receive the one-time dose, 30 Special Ops veterans traveled to a treatment site in Mexico where ibogaine use is unregulated.

Using a new technology developed at MIT, diagnosing lung cancer could become as easy as inhaling nanoparticle sensors and then taking a urine test that reveals whether a tumor is present.

A recent study reveals that the monkeypox, or mpox, virus is evolving into multiple strains due to mutations caused by ongoing interactions with the human immune system, suggesting that the virus has been circulating in humans since 2016.

“These observations of sustained MPXV transmission present a fundamental shift to the perceived paradigm of MPXV epidemiology as a zoonosis and highlight the need for revising public health messaging around MPXV as well as outbreak management and control,” write the authors.

A history-making mission to send a commercial lander to the moon is set to carry DNA to the final frontier.

Smartphone apps can differentiate between tuberculosis and other respiratory conditions. It’s part of an AI-driven trend: using sound to diagnose illnesses.

Researchers from Harvard SEAS and Boston University reveal its transformative effects, offering newfound mobility and independence for individuals with this debilitating condition.

The wearable tech successfully eliminates a common symptom called ‘gait freezing’ to restore smooth strides for Parkinson’s disease sufferers.

😀 They say we could even regenerate human limbs this way aswell as repair human blood vessels.

Cell tubes, made entirely from a patient’s own cells, are just as elastic as blood vessels but much stronger. Skin cells cultured into lumps are skewered on needles on a base, similar to a Kenzan, a tool used in Japanese flower arrangements, and formed into a tube. The technique, called the Kenzan Method, was made possible by a 3D bioprinter. A clinical trial is underway in Japan to transplant these tubes into humans in place of blood vessels. Studies are being done to apply them to nerves and organs.