Lifeboat Foundation

𝐅𝐨𝐫 𝐭𝐡𝐞 𝐟𝐢𝐫𝐬𝐭 𝐭𝐢𝐦𝐞, 𝐚 𝐭𝐞𝐚𝐦 𝐨𝐟 𝐫𝐞𝐬𝐞𝐚𝐫𝐜𝐡𝐞𝐫𝐬 𝐡𝐚𝐬 𝐨𝐛𝐬𝐞𝐫𝐯𝐞𝐝 𝐜𝐡𝐚𝐧𝐠𝐞𝐬 𝐢𝐧 𝐡𝐨𝐰 𝐝𝐢𝐟𝐟𝐞𝐫𝐞𝐧𝐭 𝐩𝐚𝐫𝐭𝐬 𝐨𝐟 𝐭𝐡𝐞 𝐛𝐫𝐚𝐢𝐧 𝐢𝐧𝐭𝐞𝐫𝐚𝐜𝐭 𝐰𝐢𝐭𝐡 𝐞𝐚𝐜𝐡 𝐨𝐭𝐡𝐞𝐫 𝐚𝐟𝐭𝐞𝐫 𝐚 𝐩𝐞𝐫𝐬𝐨𝐧’𝐬 𝐛𝐨𝐝𝐲 𝐢𝐬 𝐢𝐦𝐦𝐞𝐫𝐬𝐞𝐝 𝐢𝐧 𝐜𝐨𝐥𝐝 𝐰𝐚𝐭𝐞𝐫. 𝐓𝐡𝐞 𝐟𝐢𝐧𝐝𝐢𝐧𝐠𝐬 𝐞𝐱𝐩𝐥𝐚𝐢𝐧 𝐰𝐡𝐲 𝐩𝐞𝐨𝐩𝐥𝐞 𝐨𝐟𝐭𝐞𝐧 𝐟𝐞𝐞𝐥 𝐦𝐨𝐫𝐞 𝐮𝐩𝐛𝐞𝐚𝐭 𝐚𝐧𝐝 𝐚𝐥𝐞𝐫𝐭 𝐚𝐟𝐭𝐞𝐫 𝐬𝐰𝐢𝐦𝐦𝐢𝐧𝐠 𝐨𝐮𝐭𝐬𝐢𝐝𝐞 𝐨𝐫 𝐭𝐚𝐤𝐢𝐧𝐠 𝐜𝐨𝐥𝐝 𝐛𝐚𝐭𝐡𝐬.

During a research trial, the results of which are published in the journal Biology, healthy volunteers were given a functional MRI (fMRI) scan immediately after bathing in cold water. These scans revealed changes in the connectivity between the parts of the brain that process emotions.

For the first time, a team of researchers has observed changes in how different parts of the brain interact with each other after a person’s body is immersed in cold water. The findings explain why people often feel more upbeat and alert after swimming outside or taking cold baths.

Continue reading “MRI scans reveal changes in brains wiring after cold water shock” »

An excellent overview of the story of how the U.S. responded to the COVID-19 pandemic along with suggestions for ways to continue making strides in combatting SARS-CoV-2 as well as how we may prepare for future emerging pathogens. The article provides an interesting case study on mechanisms of large-scale human organization, examines ways that we have succeeded in managing so many moving pieces, and explores ways that we could do better in the future. #nih #health #medicine #government #biotechnology

Investment, collaboration, and coordination have been key.

Francis Collins [email protected], Stacey Adam, […], Christine Colvis, Elizabeth Desrosiers, […], Ruxandra Draghia-Akli, Anthony Fauci, Maria Freire, Gary Gibbons, Matthew Hall, […], Eric Hughes, Kathrin Jansen, Michael Kurilla, H. Clifford Lane, Douglas Lowy, Peter Marks, Joseph Menetski, William Pao, Eliseo Pérez-Stable, Lisa Purcell, Sarah Read, Joni Rutter, Michael Santos, Tara Schwetz, Jeffrey Shuren, Timothy Stenzel, Paul Stoffels, Lawrence Tabak, Karen Tountas, Bruce Tromberg, David Wholley, Janet Woodcock, and John Young +29 authors +27 authors +22 authors fewer Authors Info & Affiliations

Continue reading “The NIH-led research response to COVID-19” »

Chinese geneticist He Jiankui rocked the scientific world with his gene-edited baby experiments back in 2018, a highly controversial use of the technology that ended up sending him to a three-year stint in prison for illegal medical practices.

Now, just under a year after being released, He has some regrets about rushing into the experiments.

“I did it too quickly,” He told the South China Morning Post in a new interview.

New work shows that histones, long treated as boring spools for DNA, sit at the center of the origin story of eukaryotes and continue to play important roles in evolution and disease.

Gabriel kreiman; harvard university, children’s hospital boston.

—THE STUDY ESTABLISHES A NOVEL CONCEPT OF “TUMOR SUPPRESSIVE DRUG RESISTANCE”

—THE COMBINATION OF LB-100 WITH INHIBITORS OF CELLULAR STRESS RESPONSE MODULATORS WAS HIGHLY EFFECTIVE IN KILLING CANCER CELLS IN SEVERAL PRE-CLINICAL CANCER MODELS

—RESISTANCE TO THIS THERAPY CAN RESULT IN THE LOSS OF THE ONCOGENIC PROPERTIES OF CANCER CELLS

How DAOs can change the face of science.

People can lower their risks of getting many common kinds of cancer by making healthy choices. Screening tests can find some cancers early when treatment works best. Vaccines (shots) can help prevent several kinds of cancer. Learn more about how to lower your risk of getting cancer.

Dr. Loren Mosher, in an interview for “Changing Our Minds” (http://www.changingourmindsmovie.com for complete DVD), a documentary on mental health, talks about the Soteria project, a long term study on alternative, non-neuroleptic drug treatments for schizophrenia. Purchase the complete DVD at http://www.changingourmindsmovie.com