Lifeboat Foundation

The more crops we cultivate, the less chance our food supply wil get wiped out by a disease.

Out of the more than 300,000 plant species in existence, only three species—rice, wheat, and maize—account for most of the plant matter that humans consume, partly because in the history of agriculture, mutations arose that made these crops the easiest to harvest. But with CRISPR technology, we don’t have to wait for nature to help us domesticate plants, argue researchers at the University of Copenhagen. In a Review published March 2 in Trends in Plant Science, they describe how gene editing could make, for example, wild legumes, quinoa, or amaranth, which are already sustainable and nutritious, more farmable.

“In theory, you can now take those traits that have been selected for over thousands of years of crop domestication—such as reduced bitterness and those that facilitate easy harvest—and induce those mutations in plants that have never been cultivated,” says senior author Michael Palmgren, a botanist who heads an interdisciplinary think tank called “Plants for a Changing World” at the University of Copenhagen.

Continue reading “Want more crop variety? Researchers propose using CRISPR to accelerate plant domestication” »

Humanoid robots may enhance growth of musculoskeletal tissue grafts for tissue transplant applications.

Over the past decade, exciting progress has been made in the development of humanoid robots. The significant potential future value of humanoids includes applications ranging from personal assistance to medicine and space exploration. In particular, musculoskeletal humanoids (such as Kenshiro and Eccerobot) were developed to interact with humans in a safer and more natural way (1, 2). They aim to closely replicate the detailed anatomy of the human musculoskeletal system including muscles, tendons, and bones.

With their structures activated by artificial muscles, musculoskeletal humanoids have the ability to mimic more accurately the multiple degrees of freedom and the normal range of forces observed in human joints. As a result, it is not surprising that they offer new opportunities in science and medicine. Here, we suggest that musculoskeletal robots may assist in the growth of musculoskeletal tissue grafts for tissue transplant applications.

The woolly mammoth has been extinct for more than 4000 years. Now scientists are talking about bringing it back with the help of a powerful gene-editing technique called CRISPR-Cas9.

But CRISPR’s promise extends far beyond the possibility to resurrect extinct animals. It may also have the potential to boost crop yields and create alternatives fuel sources, protect us from insect-borne scourges like malaria and Zika, and even cure cancer.

A core set of genes involved in the responses of honey bees to multiple diseases caused by viruses and parasites has been identified by an international team of researchers. The findings provide a better-defined starting point for future studies of honey-bee health, and may help scientists and beekeepers breed honey bees that are more resilient to stress.

“In the past decade, honey-bee populations have experienced severe and persistent losses across the Northern Hemisphere, mainly due to the effects of pathogens, such as fungi and viruses,” said Vincent Doublet, postdoctoral research fellow, University of Exeter. “The genes that we identified offer new possibilities for the generation of honey-bee stocks that are resistant to these pathogens.”

According to the researchers, recent advances in DNA sequencing have prompted numerous investigations of the genes involved in honey-bee responses to pathogens. Yet, until now, this vast quantity of data has been too cumbersome and idiosyncratic to reveal overarching patterns in honey-bee immunity.

Continue reading “Scientists reveal core genes involved in immunity of honey bees” »

Research from McMaster University has found that bacteria in the gut impacts both intestinal and behavioural symptoms in patients suffering from irritable bowel syndrome (IBS), a finding which could lead to new microbiota-directed treatments.

The new study, published today in Science Translational Medicine, was led by researchers from the Farncombe Family Digestive Health Research Institute at McMaster, Drs. Premysl Bercik and Stephen Collins, in collaboration with researchers from the University of Waterloo.

IBS is the most common gastrointestinal disorder in the world. It affects the large intestine and patients suffer from abdominal pain and altered bowel habits like diarrhea and constipation, which are often accompanied by chronic anxiety or depression. Current treatments aimed at improving symptoms have limited efficacy because the underlying causes are unknown.

Continue reading “Intestinal bacteria alter gut and brain function” »

Dangerous thought.

The scientific world was set ablaze of late as discussions ramped up about the resurrection of the wholly mammoth. I know what you’re thinking: Jurassic Park. Well, not quite — but maybe not that far off, either. Dr. Michio Kaku, professor of theoretical physics at the City College of New York, wonders: what if we could clone the Neanderthal, or a dinosaur, based solely off their genomes?

Continue reading “Forget Mammoths, We Could Bring Dinosaurs and Neanderthals Back to Life” »

A 3D bioprinter able to create human skin is already being used to help burns patients and carry out skin testing, Alfredo Brisac, CEO of Spanish bioengineering company BioDan, told Radio Sputnik.

Last month, scientists at Universidad Carlos III de Madrid and the BioDan Group presented a prototype 3D bioprinter that can create human skin suitable for transplantation to patients or for use in cosmetic, chemical or pharmaceutical testing.

One of the first living human organs to be created using bioprinting, the 3D-printed skin is created using bio-inks with living cells that are deposited onto a structure that replicates nature. The bio-ink contains the key elements of keratinocytes, fibroblasts and fibrin, which can recreate the structure of the skin.

BOISE, Idaho (AP) — Three types of potatoes genetically engineered to resist the pathogen that caused the Irish potato famine are safe for the environment and safe to eat, federal officials have announced.

The approval by the U.S. Environmental Protection Agency and the U.S. Food and Drug Administration late last week gives Idaho-based J.R. Simplot Company permission to plant the potatoes this spring and sell them in the fall.

The company said the potatoes contain only potato genes, and that the resistance to late blight, the disease that caused the Irish potato famine, comes from an Argentine variety of potato that naturally produced a defense.

Continue reading “US approves 3 types of genetically engineered potatoes” »

New research describes a novel 3D printing technique for the production of smart materials that may find use in soft-robotics and advanced medicine.

In a recent academic paper the, “striking phenomena” that “can be produced by embedding magnetic particles into polymer with designed patterns,” are described in detail. These phenomena include smart materials with, “tunable elastic properties, giant deformational effects, high elasticity, anisotropic elastic and swelling properties, and quick response to magnetic fields.”

As previously reported by 3D Printing Industry, investigations into smart and meta materials are increasingly using 3D printing techniques.

Continue reading “Novel 3D printing technique uses magnets to create smart materials for soft robotics and medicine” »