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Archive for the ‘biotech/medical’ category: Page 902

Aug 26, 2022

Existential Hope Special with Morgan Levine | On the Future of Aging

Posted by in categories: biotech/medical, genetics, life extension, mathematics, robotics/AI

Foresight Existential Hope Group.
Program & apply to join: https://foresight.org/existential-hope/

In the Existential Hope-podcast (https://www.existentialhope.com), we invite scientists to speak about long-termism. Each month, we drop a podcast episode where we interview a visionary scientist to discuss the science and technology that can accelerate humanity towards desirable outcomes.

Continue reading “Existential Hope Special with Morgan Levine | On the Future of Aging” »

Aug 26, 2022

Small devices letting patients collect diagnostics quality blood samples

Posted by in category: biotech/medical

Small devices letting patients collect diagnostics quality blood samples at home were getting lots of publicity in the past few months, as they are finding their way into clinical trials and are available as direct-to-consumer products. We asked Dr Erwin Berthier, CTO and Co-Founder of Tasso about the technology.

You can read the exclusive interview on our Patreon page. Thank you for your support!

https://www.patreon.com/posts/70639361

Aug 26, 2022

This lifesaving tool has a 20-ton cutting force that can shear you out of danger

Posted by in category: biotech/medical

Credit: Savetool

Aug 26, 2022

Reversed Halo Sign in Invasive Pulmonary Fungal Infections

Posted by in category: biotech/medical

face_with_colon_three circa 2008.


Opportunistic fungal pneumonias are associated with high morbidity and mortality rates [ 1–3]. Although invasive pulmonary aspergillosis (IPA) is the most common type of fungal pneumonia, other angioinvasive molds, such as Fusarium and Zygomycetes species, are increasingly encountered in severely immunocompromised hosts. Because early institution of high-dose antifungal therapy is associated with improved outcomes [ 4, 5], early recognition of invasive fungal disease is important. However, cultures of respiratory secretions are neither sensitive nor specific, and lavage and invasive procedures often cannot be done for these patients because of coagulation abnormalities and thrombocytopenia [ 6, 7]. Thus, diagnosis of invasive pulmonary fungal disease relies heavily on imaging [ 8]. CT is often used in an attempt to identify fungal pneumonia in a timely fashion.

The reversed halo sign (RHS) is a CT finding, a focal round area of ground-glass attenuation surrounded by a ring of consolidation, which has been described in cryptogenic organizing pneumonia [ 9, 10].

Continue reading “Reversed Halo Sign in Invasive Pulmonary Fungal Infections” »

Aug 26, 2022

This Newly-Approved Drug Can Keep Chronic Yeast Infections Away for 2 Years

Posted by in category: biotech/medical

Vivjoa (oteseconazole) is the first and only FDA approved medication for chronic yeast infections. Here’s what you need to know about the medication.

Aug 26, 2022

Stem Cells Build a Better Rat Penis

Posted by in category: biotech/medical

Circa 2002 face_with_colon_three


New approach could help men with injuries or deformities.

Aug 26, 2022

Interview w/ Prof. Lee Smolin on Parkinson’s and getting a Deep Brain Stimulator implanted yesterday

Posted by in categories: biotech/medical, neuroscience

Just yesterday (2022−08−24) Prof. Smolin had a deep brain stimulator inserted into his left Globus Pallidus to help him better manage his symptoms of Parkinson’s Disease. Here he talks about that day, his theory of PD and the journey he had been on to getting DBS.

Aug 25, 2022

Scientists Grew a Synthetic Mouse Embryo With a Brain And a Beating Heart

Posted by in categories: biotech/medical, neuroscience

Eavesdropping on the earliest conversations between tissues in an emerging life could tell us a lot about organ growth, fertility, and disease in general. It could help prevent early miscarriages, or even tell us how to grow whole replacement organs from scratch.

In a monumental leap in stem cell research, an experiment led by researchers from the University of Cambridge in the UK has developed a living model of a mouse embryo complete with fluttering heart tissues and the beginnings of a brain.

The research advances the recent success of a team comprised of some of the same scientists who pushed the limits on mimicking the embryonic development of mice using stem cells that had never seen the inside of a mouse womb.

Aug 25, 2022

Discovery of the cell fate switch from neurons to astrocytes in the developing brain

Posted by in categories: biotech/medical, neuroscience

During mammalian brain development, neural precursor cells first generate neurons and later astrocytes. This cell fate change is a key process generating proper numbers of neurons and astrocytes. Here we discovered that FGF regulates the cell fate switch from neurons to astrocytes in the developing cerebral cortex using mice. FGF is a critical extracellular regulator of the cell fate switch, necessary and sufficient, in the mammalian cerebral cortex.

Neurons and astrocytes are prominent cell types in the . Neurons are the primary information processing cells in the , whereas astrocytes support and modulate their functions. For sound functioning of the brain, it is crucial that proper numbers of neurons and astrocytes are generated during fetal brain development. The brain could not function correctly if only neurons or astrocytes were generated.

During fetal brain development, both neurons and astrocytes are generated from , which give rise to almost all cells in the cerebral cortex (Figure 1). One of the characteristics of this developmental process is that neural stem cells first generate neurons and, after that, start generating astrocytes (Figure 1). The “switch” to change the cell differentiation fate of neural stem cells from neurons to astrocytes has attracted much attention, since the cell fate switch is key to the generation of proper numbers of neurons and astrocytes. However, it remained largely unknown.

Aug 25, 2022

New insight into the generation of new neurons in the adult brain

Posted by in categories: biotech/medical, neuroscience

Researchers at Sahlgrenska Academy at the University of Gothenburg, Sweden, in collaboration with research groups in Finland, Canada and Slovenia, have discovered a novel and unexpected function of nestin, the best-known marker of neural stem cells.

In the , the three main cell types, neurons, astrocytes and oligodendrocytes, are generated from neural stem . In some such as the hippocampus, the region involved in learning and memory, new neurons are being added to the existing neuronal circuitry even in adulthood, when severe restriction of neuronal differentiation occurs.

Using mice deficient in nestin, a protein that is a component of the part of the cytoskeleton known as or nanofilaments, the research team led by Prof. Milos Pekny showed that nestin produced in astrocytes has an important role in inhibiting neuronal differentiation. They linked this regulatory function of nestin to the Notch signaling from astrocytes to neighboring neural stem cells. Thus, surprisingly, nestin does not control the generation of neurons by acting within neural stem cells, but indirectly by regulating the neurogenesis-inhibitory Notch signals that receive from astrocytes, important constituents of the neurogenic niche.

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