Lifeboat Foundation

Neuralink says it has successfully implanted another brain chip in a human patient.

According to a study update shared by the company, the patient, identified by his first name, Alex, has been improving his ability to play video games and has started learning how to use design software to create 3D objects.

The company said the procedure “went well,” and Alex’s recovery “has been smooth.”

CRISPR will get easier and easier to administer. What does that mean for the future of our species?

Researchers at a Swedish university have developed tiny robots that can kill cancerous tumours with deadly precision.

The detection of individual particles and molecules has opened new horizons in analytical chemistry, cellular imaging, nanomaterials, and biomedical diagnostics. Traditional single-molecule detection methods rely heavily on fluorescence techniques, which require labeling of the target molecules.

A Yale-led study reveals that two types of neurodevelopmental abnormalities emerging early in brain development are linked to autism, with these differences influenced by brain size.

By using brain organoids derived from autistic children’s stem cells, researchers uncovered distinct neural growth patterns, potentially guiding personalized treatments and diagnoses.

Early Brain Development and Autism.

The improved gene-editing approach combines prime editors with a more efficient recombinase to insert or substitute gene-sized DNA segments.

I don’t know what’s causing the sound problem my apologies.

Randal and Keith discuss WBE, Mind Uploading and fascinating tangents in neuroscience and neuroprosthetics and pathways for the future, as well as the Carbon Copies foundation and the new book ‘Contemplating Oblivion’ by Keith Wiley.

Continue reading “Whole Brain Emulation & Mind Uploading with Keith Wiley & Randal Koene” »

Researchers have discovered a “spatial grammar” in DNA that redefines the role of transcription factors in gene regulation, influencing our understanding of genetic variations and disease.

A recently uncovered code within DNA, referred to as “spatial grammar,” may unlock the secret to how gene activity is encoded in the human genome.

This breakthrough finding, identified by researchers at Washington State University and the University of California, San Diego and published in Nature, revealed a long-postulated hidden spatial grammar embedded in DNA. The research could reshape scientists’ understanding of gene regulation and how genetic variations may influence gene expression in development or disease.

Among the many ways neuroscientists think Alzheimer’s disease may strip away brain function is by disrupting the glucose metabolism needed to fuel the healthy brain. In essence, declining metabolism robs the brain of energy, impairing thinking and memory.

Against that backdrop, a team of neuroscientists at the Knight Initiative for Brain Resilience at Stanford’s Wu Tsai Neurosciences Institute have zeroed in on a critical regulator of brain metabolism known as the kynurenine pathway. They hypothesize that that the kynurenine pathway is over-activated as a result of amyloid plaque and tau proteins that accumulate in the brains of patients with Alzheimer’s disease.

Now, with support from research and training grants from the Knight Initiative, they have shown that by blocking the kynurenine pathway in lab mice with Alzheimer’s Disease, they can improve, or even restore, cognitive function by reinstating healthy brain metabolism.