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Researchers identified a subcortical brain network that is thought to combine arousal and awareness, playing a key role in human consciousness.

A study recently published in Science Translational Medicine by researchers from Massachusetts General Hospital and Boston Children’s Hospital, both part of the Mass General Brigham healthcare system, introduces a connectivity map of a brain network. This map, the researchers suggest, is essential for maintaining human consciousness.

The study involved high-resolution scans that enabled the researchers to visualize brain connections at submillimeter spatial resolution. This technical advance allowed them to identify previously unseen pathways connecting the brainstem, thalamus, hypothalamus, basal forebrain, and cerebral cortex.

The Rabbit R1 handheld AI device is a simple Android device, and a developer made the AI run on an iPhone.

The Rabbit R1 offers the ability to answer queries and perform tasks using AI, instead of using an iPhone directly. However, the work of one enterprising developer has resulted in a clone of the “iPhone-killer” which can run on an iPhone.

In X tweets on Monday, Will Hobick of Flutterflow posted that he would be posting a “cloneable template” of the Rabbit R1 app later in the week. In a follow-up post on Tuesday, he demonstrates a version of the app running on an iPhone.

Cryptococcus accounts for up to 180,000 deaths annually and 68% of HIV-related meningitis cases. The authors of a new review discuss diagnostic, preventive, and therapeutic strategies and the pathophysiological role of inflammatory syndromes. Full review:

Researchers have discovered the process by which dietary choline crosses the blood-brain barrier. This breakthrough has potential applications in enhancing drug delivery to the brain for treating neurological disorders.

A researcher from the University of Queensland has identified molecular doorways that could facilitate the delivery of drugs to the brain for treating neurological disorders.

Dr. Rosemary Cater from UQ’s Institute for Molecular Bioscience led a team that discovered that an essential nutrient called choline is transported into the brain by a protein called FLVCR2.

Most antibiotics target metabolically active bacteria, but with artificial intelligence, researchers can efficiently screen compounds that are lethal to dormant microbes.

Since the 1970s, modern antibiotic discovery has been experiencing a lull. Now the World Health Organization has declared the antimicrobial resistance crisis as one of the top 10 global public health threats.

When an infection is treated repeatedly, clinicians run the risk of bacteria becoming resistant to the antibiotics. But why would an infection return after proper antibiotic treatment? One well-documented possibility is that the bacteria are becoming metabolically inert, escaping detection of traditional antibiotics that only respond to metabolic activity. When the danger has passed, the bacteria return to life and the infection reappears.

A study in Nature identifies molecular responses to endurance exercise training in rats, including sex-specific responses. The findings may offer new insights into the impact of exercise on health and disease. Read the paper:

Temporal multi-omic analysis of tissues from rats undergoing up to eight weeks of endurance exercise training reveals widespread shared, tissue-specific and sex-specific changes, including immune, metabolic, stress response and mitochondrial pathways.

Some of the AI-designed gene editors could be more versatile than those found in nature.

Researchers at Umeå University, Sweden, have discovered that how a special protein complex called the Mediator moves along genes in DNA may have an impact on how cells divide. The discovery may be important for future research into the treatment of certain diseases. The study is published in Nucleic Acids Research.

Experts say the food on your plate can affect everything from your bones, heart, and gut to your mental health.