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As our devices get smaller and smaller, the use of molecules as the main components in electronic circuitry is becoming ever more critical. Over the past 10 years, researchers have been trying to use single molecules as conducting wires because of their small scale, distinct electronic characteristics, and high tunability. But in most molecular wires, as the length of the wire increases, the efficiency by which electrons are transmitted across the wire decreases exponentially. This limitation has made it especially challenging to build a long molecular wire—one that is much longer than a nanometer—that actually conducts electricity well.

Columbia researchers announced today that they have built a nanowire that is 2.6 nanometers long, shows an unusual increase in conductance as the wire length increases, and has quasi-metallic properties. Its excellent conductivity holds great promise for the field of molecular electronics, enabling electronic devices to become even tinier. The study is published today in Nature Chemistry.

Scientists at Tokyo Institute of Technology designed a new type of molecular wire doped with organometallic ruthenium to achieve unprecedentedly higher conductance than earlier molecular wires. The origin of high conductance in these wires is fundamentally different from similar molecular devices and suggests a potential strategy for developing highly conducting “doped” molecular wires.

Since their conception, researchers have tried to shrink electronic devices to unprecedented sizes, even to the point of fabricating them from a few molecules. Molecular wires are among the building blocks of such minuscule contraptions, and many researchers have been developing strategies to synthesize highly conductive, stable wires from carefully designed molecules.

A team of researchers from Tokyo Institute of Technology, including Yuya Tanaka, designed a novel in the form of a metal electrode-molecule-metal electrode (MMM) junction including a polyyne, an organic chain-like molecule, “doped” with a ruthenium-based unit Ru(dppe)2. The proposed design, featured in the cover of the Journal of the American Chemical Society, is based on engineering the energy levels of the conducting orbitals of the atoms of the wire, considering the characteristics of gold electrodes.

Circa 2020


A little while ago, we covered the idea of using photovoltaic materials to drive enzymatic reactions in order to produce specific chemicals. The concept is being considered mostly because doing the same reaction in a cell is often horribly inefficient, because everything else in the cell is trying to regulate the enzymes, trying to use the products, trying to convert the byproducts into something toxic, or up to something even more annoying. But in many cases, these reactions rely on chemicals that are only made by cells, leaving some researchers to suspect it still might be easier to use living things in the end.

Everything we know, think and feel—everything!—comes from our brains. But consciousness, our private sense of inner awareness, remains a mystery. Brain activities—spiking of neuronal impulses, sloshing of neurochemicals—are not at all the same thing as sights, sounds, smells, emotions. How on earth can our inner experiences be explained in physical terms?

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Peter Ulric Tse is Professor of Cognitive Neuroscience in the department of Psychological and Brain Sciences at Dartmouth College. He holds a BA from Dartmouth (1984; majored in Mathematics and Physics), and a PhD in Experimental Psychology from Harvard University (1998).

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Closer to Truth, hosted by Robert Lawrence Kuhn and directed by Peter Getzels, presents the world’s greatest thinkers exploring humanity’s deepest questions. Discover fundamental issues of existence. Engage new and diverse ways of thinking. Appreciate intense debates. Share your own opinions. Seek your own answers.

How does the human brain work and how is it different from computers? If you think this is too complex to explain in a few minutes, you will be surprised. In this energetic and insightful talk, neuro-scientist Dr. Henning Beck gives insights into thought processes and tells you how you can create new ideas.

Dr. Henning Beck, neuroscientist and author, supports businesses to use brain-based approaches in order to develop innovative and efficient workflows. He studied biochemistry in Tübingen from 2003 to 2008. After his diploma thesis, he started his research at the Hertie Institute for Clinical Brain Research and intensified his work at the Institute of Physiological Chemistry at the University of Ulm. Supported by a PhD scholarship granted by the Hertie Foundation he did his doctorate at the Graduate School of Cellular & Molecular Neuroscience in Tübingen. He expanded his scientific expertise by an International Diploma in Project Management at the University of California, Berkeley in 2013. Until 2014, he worked for start-ups in the San Francisco Bay Area to develop creative workspace designs and advanced communication styles based on neuroscientific principles.

This talk was given at a TEDx event using the TED conference format but independently organized by a local community.

As you’re reading this sentence, the cells in your brain, called neurons, are sending rapid-fire electrical signals between each other, transmitting information. They’re doing so via tiny, specialized junctions between them called synapses.

There are many different types of that form between neurons, including “excitatory” or “inhibitory,” and the exact mechanisms by which these structures are generated remain unclear to scientists. A Colorado State University biochemistry lab has uncovered a major insight into this question by showing that the types of chemicals released from synapses ultimately guide which kinds of synapses form between neurons.

Soham Chanda, assistant professor in the Department of Biochemistry and Molecular Biology, led the study published in Nature Communications that demonstrates the possibility of changing the identity of synapses between neurons, both in vitro and in vivo, through enzymatic means. The other senior scientists who contributed to the project were Thomas Südhof of Stanford University and Matthew Xu-Friedman of the University at Buffalo.

We have developed a new method to look for carbon compounds in space, akin to prospecting for oil on Earth. Our method is published in Monthly Notices of the Royal Astronomical Society.

Between the stars lie vast amounts of interstellar gas and , spread thinly throughout our galaxy. The dust can contain compounds of carbon. When it does we call it carbonaceous interstellar dust. This is an important reservoir for the in space. The continual cycle of material between the stars and the gas in the interstellar medium in our galaxy leads to the delivery of organic molecules to newly forming planetary systems.

A special sub-class of organic molecules called prebiotic molecules are thought to play a major role in the formation of life on Earth. Such prebiotic molecules are likely preserved in carbonaceous interstellar dust that are gathered together in planetesimals, in an early stage of planetary formation. The in such environments may determine the planet’s hospitality to the formation of life there. Therefore, it is important to understand the life cycle of carbonaceous interstellar dust to study this possibility further.

Despite the fact that sex is a basic instinct and a near-universal experience, we know remarkably little about it. And so, this week, we’re teaming up with our friends at Futurism, oracles of all things science, technology and medicine, to look at the past, present and future of pleasure from a completely scientific perspective.

For a while now, the neurotransmitter dopamine has been seen as the conductor of good feelings. It’s the subject of love songs, the seductress of biohackers and the ostensible “pleasure chemical.” But as research continues to uncover more about our brain’s reward system, dopamine is beginning to look less like the maestro and more like a member of the band.