Lifeboat Foundation: Safeguarding Humanity
Toggle light / dark theme

Blog

Category: chemistry – Page 234

A new study says that changing guidelines for forever chemicals have made rainwater all around the world unsafe to drink.

Rainwater is an important part of our planet’s ecosystem, and it helps fuel access to drinking water in many places. However, a new study suggests that rainwater is now unsafe to drink. The study says that “forever chemicals” have reached unsafe levels. These forever chemicals are scientifically known as per-and poly-fluoroalkyl substances (PFAS), and they don’t break down in the environment.

You can find PFAS chemicals in non-stick and stain-repellent properties. As such, they’re found in a lot of household food packages, electronics, and even cosmetics and cookware. However, it seems that these chemicals are now mixing with our rainwater. As a result, it has made rainwater unsafe to drink. And researchers say they can’t tie this issue to just one location. It’s everywhere in the world, even in Antarctica.

The researchers say that the guideline levels for forever chemicals have dropped significantly over the past 20 years. That’s because new insight into just how toxic these chemicals are to the human body has come to light. As such, the values for PFAS in drinking water to be considered toxic have dropped quite a bit. As a result, the current levels of one particular chemical would deem rainwater unsafe to drink.

Read more | >

Circa 2021 Basically this article details cannabinoids that have been successfully synthesized which can lead to even greater psychiatric medicine aswell as many of other types of uses.

Abstract Cannabis has been integral to Eurasian civilization for millennia, but a century of prohibition has limited investigation. With spreading legalization, science is pivoting to study the pharmacopeia of the cannabinoids, and a thorough understanding of their biosynthesis is required to engineer strains with specific cannabinoid profiles. This review surveys the biosynthesis and biochemistry of cannabinoids. The pathways and the enzymes’ mechanisms of action are discussed as is the non-enzymatic decarboxylation of the cannabinoic acids. There are still many gaps in our knowledge about the biosynthesis of the cannabinoids, especially for the minor components, and this review highlights the tools and approaches that will be applied to generate an improved understanding and consequent access to these potentially biomedically-relevant materials. Graphical abstract.

Read more | >

A team of researchers in the Faculty of Engineering of The University of Hong Kong (HKU) has developed a coin-sized system that can read weak electrochemical signals and can be used for personalized health monitoring and the measurement of such conditions as diabetes, cardiovascular diseases and mental health. The discovery was featured on the cover of Analytical Chemistry.

The PERfECT System—an acronym for Personalized Electronic Reader for Electrochemical Transistors—is the world’s smallest system of its kind, measuring 1.5 cm x 1.5 cm x 0.2 cm and weighing only 0.4 gram. It is easily wearable, for instance integrated with a smartwatch or as a patch, to allow for continuous monitoring of biosignals such as glucose levels and antibody concentrations in blood and even sweat.

“Our wearable system is tiny, soft and imperceptible to wearers, and it can do continuous monitoring of our body condition. These features mean it has the potential to revolutionize health care technology,” said Dr. Shiming Zhang of the Department of Electrical and Electronic Engineering, who leads the HKU WISE (wearable, intelligent and ) Research Group to develop the system.

Read more | >

Gene therapy pioneer — dr. katherine high, MD — president, therapeutics, askbio.

Dr. Katherine High, MD, is President, Therapeutics, at Asklepios BioPharmaceutical (AskBio — https://www.askbio.com/), where she is also member of the AskBio Board of Directors, and has responsibility for driving the strategic direction and execution of pre-clinical and clinical programs of the company.

AskBio is a wholly owned and independently operated subsidiary of Bayer AG, set up as a fully integrated gene therapy company dedicated to developing life-saving medicines that cure genetic diseases.

Most recently, Dr. High was a Visiting Professor at Rockefeller University and previous to that, she served as President, Head of Research and Development, and a member of the Board of Directors at Spark Therapeutics (a subsidiary of Hoffmann-La Roche), where she directed the development and regulatory approval of Luxturna® (a gene therapy medication for the treatment of the ophthalmic condition Leber congenital amaurosis), and represents the first gene therapy for genetic disease to obtain regulatory approval in both the United States and Europe.

Dr. High was a longtime member of the faculty at the University of Pennsylvania and medical staff at The Children’s Hospital of Philadelphia, where she was also an Investigator of the Howard Hughes Medical Institute. She served a five-year term on the U.S. Food and Drug Administration Advisory Committee on Cell, Tissue and Gene Therapies and is a past president of the American Society of Gene & Cell Therapy.

Continue reading “Dr. Katherine High, MD — Gene Therapy Pioneer — President, Therapeutics, Asklepios BioPharmaceutical” | >

The world is highly dependent on fossil fuels to power its industry and transportation. These fossil fuels lead to excessive carbon dioxide emission, which contributes to global warming and ocean acidification. One way to reduce this excessive carbon dioxide emission that is harmful to the environment is through the electroreduction of carbon dioxide into value-added fuels or chemicals using renewable energy. The idea of using this technology to produce methane has attracted wide interest. However, researchers have had limited success in developing efficient catalysts for methane.

A Soochow University research team has now developed a simple strategy for creating cobalt copper alloy catalysts that deliver outstanding methane activity and selectivity in electrocatalytic carbon dioxide reduction. Their research is published in Nano Research.

Over the past 10 years, scientists have made notable progress in advancing their understanding of catalysts and applying the knowledge to their fabrication. But the catalysts that have been developed have not been satisfactory for use with methane, in terms of selectivity or current density. Despite the great insights scientists have gained, the strategies they have attempted in creating catalysts for methane are just too costly to be useful in practical applications.

Read more | >

Sustained space exploration will require infrastructure that doesn’t currently exist: buildings, housing, rocket landing pads.

So, where do you turn for construction materials when they are too big to fit in your carry-on and there’s no Home Depot in outer space?

“If we’re going to live and work on another planet like Mars or the moon, we need to make concrete. But we can’t take bags of concrete with us—we need to use local resources,” said Norman Wagner, Unidel Robert L. Pigford Chair of Chemical and Biomolecular Engineering at the University of Delaware.

Read more | >

Specific proteins in prokaryotes detect viruses in unexpectedly direct ways.

Bacteria use a variety of defense strategies to fight off viral infection. STAND ATPases in humans are known to respond to bacterial infections by inducing programmed cell death in infected cells. Scientists predict that many more antiviral weapons will be discovered in the microbial world in the future. Scientists have discovered a new unexplored microbial defense system in bacteria.

Researchers uncovered specific proteins in prokaryotes (bacteria and archaea) that detect viruses in unexpectedly direct ways, recognizing critical parts of the viruses and causing the single-celled organisms to commit suicide to stop the infection within a microbial community, according to a press release published in the official website of the Massachusetts Institute of Technology (MIT) on Thursday.

The discovery was made by a team of scientists led by researchers at the Broad Institute of MIT and Harvard and the McGovern Institute for Brain Research at MIT.

“This work demonstrates a remarkable unity in how pattern recognition occurs across very different organisms,” said Feng Zhang, senior author and James, and Patricia Poitras Professor of Neuroscience at MIT.

“It’s been very exciting to integrate genetics, bioinformatics, biochemistry, and structural biology approaches in one study to understand this fascinating molecular system.”

Bacteria use a variety of defense strategies to fight off viral infection, and some of these systems have led to groundbreaking technologies, such as CRISPR-based gene editing.

Continue reading “MIT researchers discover bacteria’s new antiviral defense system” | >

Circa 2017

There are many theories about how life evolved on the planet Earth, from formation under a layer of ice, protected from the UV radiation above, to vents in the deep sea that provided hydrogen-rich molecules. But now one team of scientists has found quantitative results that support a theory that is literally out of this world. Organic molecules from meteorites that landed in small, warm pools of water may have delivered the ingredients necessary for life to form on Earth.

The team reached this conclusion through a mathematical model. They took data about planet formation, geology, biology and chemistry and inputted these factors into a grand quantitative model they had designed. Their results support the theory that RNA polymers formed in small, warm ponds of water. Meteorites contributed to this process by transferring enough organic molecules to these pools to ensure that RNA started self-replicating in at least one pool.

What’s more, the team discovered that, according to their calculations, life may have have begun on Earth rather early. The process may have started just a few hundred million years after the planet cooled sufficiently to support liquid surface water. The results were published in Proceedings of the National Academy of Sciences.

Read more | >