Lifeboat Foundation

A team of researchers from several institutions in Iceland and the U.S. has conducted a unique blood serum investigation and discovered multiple protein networks that are involved in the aging process. In their paper published in the journal Science, the group describes their study and what they found.

Prior research has shown that when older mice have their blood systems connected to younger mice, the older mice experience improvements in age-related organ deterioration. This finding has led scientists to suspect that aging might be caused by something in the blood. In this new effort, the researchers sought to test this idea by studying proteins in the circulatory system.

The study consisted of analyzing blood samples from 5,457 people living in Iceland, all of whom were over the age of 65 and who were participants in an ongoing study called Age, Gene/Environment Susceptibility. The volunteers had also been chosen specifically to represent a cross section of the people living in Iceland. The major part of the blood analysis involved creating a panel of DNA aptamers (short sequences that bind to proteins) that could be used to recognize proteins, both known and unknown. Blood serum from the volunteers was then compared against the panels and the results were analyzed by a computer looking for patterns.

Continue reading “Blood serum study reveals networks of proteins that impact aging” »

A new bill aims to support a growing quantum industry by training a new cross-disciplinary workforce.

This article is part of a series about how OS Fund (OSF) companies are radically redefining our future by rewriting the operating systems of life. Or as we prefer to think about it: Step 1: Put a dent into the universe. And Step 2: Rewrite the universe. You can see the full OSF collection here and read more about Building a Biological Immune System.

In contemplating the future, I love imagining how our daily lives today will be thought of in the future. What appears sci-fi to us today but will be “normal” 50 years from now? What inefficient and boneheaded things do we do today that future generations will look back and laugh at?

Continue reading “Beyond the Hard Drive: Encoding Data in DNA” »

OS Fund invests in quantum-leap developments that promise to rewrite the operating systems of life.

The Defense Advanced Research Projects Agency (DARPA) has selected the teams for two research programs that the agency hopes will provide technologies to transcend the limits of Moore’s Law.

As part of DARPA’s $1.5 billion Electronics Resurgence Initiative (ERI) to “jumpstart innovation in the electronics industry,” the Three Dimensional Monolithic System-on-a-Chip (3DSoC) program and the Foundations Required for Novel Compute (FRANC) program are focused on developing chip-level innovations that lead to more powerful and efficient computing systems. We reported on both programs last September, just after they were announced.

Last week, during DARPA’s first ERI Summit in San Francisco, the agency revealed the research teams selected to drive each of these efforts. For the 3DSoC program, groups from the Georgia Institute of Technology, Stanford University, Massachusetts Institute of Technology, and Skywater Technology Foundry were tapped. The corresponding research teams for the FRANC program will come from HRL Laboratories; Applied Materials, Inc.; Ferric, Inc.; the University of California, Los Angeles; the University of Minnesota; and the University of Illinois at Urbana-Champaign.

Continue reading “DARPA Picks Research Teams for Post-Moore’s Law Work” »

Next time you eat a blueberry (or chocolate chip) muffin consider what happened to the blueberries in the batter as it was baked. The blueberries started off all squished together, but as the muffin expanded they started to move away from each other. If you could sit on one blueberry you would see all the others moving away from you, but the same would be true for any blueberry you chose. In this sense galaxies are a lot like blueberries.

Since the Big Bang, the universe has been expanding. The strange fact is that there is no single place from which the universe is expanding, but rather all galaxies are (on average) moving away from all the others. From our perspective in the Milky Way galaxy, it seems as though most galaxies are moving away from us – as if we are the centre of our muffin-like universe. But it would look exactly the same from any other galaxy – everything is moving away from everything else.

To make matters even more confusing, new observations suggest that the rate of this expansion in the universe may be different depending on how far away you look back in time. This new data, published in the Astrophysical Journal, indicates that it may time to revise our understanding of the cosmos.

Continue reading “New Physics Needed to Resolve Universe Expansion Debate?” »

The strange case of a young boy who had a large section of his brain removed shows just how good the human brain is at repairing itself — or at least making the most of a tough situation. Beyond being just a lump of tissue that named itself, the brain is also a kind of wonderful, wet computer that’s capable of rewiring itself in response to new experiences like taking drugs, forming new memories, and making friends. In extreme cases, like that of a 6-year-old boy who had about one-sixth of his brain removed, the brain can even adapt to getting cut apart.

Doctors documented the boy’s case in a paper published July 31 in the journal Cell Reports. They report that despite the boy having a significant portion of his brain removed, including the portion associated with visual processing, the boy has developed into a healthy 10-year-old. And while he still can’t see in the left side of his field of vision, his brain has reconfigured some of the lost connections so that he is able to recognize people’s faces. All in all, the doctors see it as a successful procedure, as well as evidence of the brain’s plasticity — its ability to adapt — when it comes to higher-order functions.

“He is essentially blind to information on the left side of the world. Anything to the left of his nose is not transmitted to his brain, because the occipital lobe in his right hemisphere is missing and cannot receive this information,” Marlene Behrmann, Ph.D., a professor of psychology at Carnegie Mellon University and the corresponding author on the paper, tells New Scientist.

Continue reading “Boy Who Had a Chunk of Brain Removed Turned Out Healthy” »

18-year-old Ewin Tang has proven that classical computers can solve the “recommendation problem” nearly as fast as quantum computers. The result eliminates one of the best examples of quantum speedup.

Silicon is the king of the computing world. Almost all commercial integrated circuits have been based on silicon and, for the most part, on a single basic process called complementary metal oxide (CMOS).

But the end of silicon may be in sight. Even industry giant IBM acknowledges that silicon’s days are numbered. But why? And what’s going to replace it?

There is a whole raft of new materials and partial replacements for silicon in the offing. But I could have written that very sentence two decades ago—maybe even as far back as 1980. Yet silicon remains dominant.