Circa 2019
Mark Lawrence (link is external), a postdoctoral scholar in materials science and engineering at Stanford, has moved a step closer to this future with a scheme to make a photon diode — a device that allows light to only flow in one direction — which, unlike other light-based diodes, is small enough for consumer electronics.
Our cells perform a marvel of engineering when it comes to packing information into small spaces. Every time a cell divides, it bundles up an amazing 4 metres of DNA into 46 tiny packages, each of which is only several millionths of a metre in length. Researchers from EMBL Heidelberg and the Julius-Maximilians-Universität Würzburg have now discovered how a family of DNA motor proteins succeeds in packaging loosely arranged strands of DNA into compact individual chromosomes during cell division.
The researchers studied condensin, a protein complex critical to the process of chromosome formation. Although this complex was discovered more than three decades ago, its mode of action remained largely unexplored. In 2018, researchers from the Häring group at EMBL Heidelberg and their collaborators showed that condensin molecules create loops of DNA, which may explain how chromosomes are formed. However, the inner workings by which the protein complex achieves this feat remained unknown.
Continue reading “How the Genome Shapes Up for Cell Division” »
A non-profit organization merges engineering and biology to accelerate drug development for childhood cancers.
Lamborghinis are already marvels of engineering but they become even more so when people decide to upgrade them. This is what designer Michael Hritzkrieg did with this new model called the Lamborghini LMXX2.
You can see from the pictures that it’s got some impressive treads that run all around the car making it clear that it can tackle even the most difficult terrains such as sands, rocks and soil. IE spoke to Hritzkrieg about his innovative design and he surprisingly described it as “a rush job to meet an Instagram competition deadline.”
The competition he is referring to is the AGP Contest on Instagram which asked participants to conceive of a design using the keywords “Desert + Lamborghini + Future”.
A model attributes the propagating bands that appear in a compressed porous medium to structural changes alone.
Porous media such as snow, sand, cereals—even bones—develop strikingly similar banded patterns when they’re squeezed. Those bands form when localized deformation zones propagate throughout the material. Understanding what triggers the universal and “material-agnostic” emergence of the bands is a common goal in disciplines including avalanche research, petroleum extraction, structural engineering, geophysics, and agriculture. Now, describing the phenomenon using a model based entirely on a collapsing-pore mechanism, Lars Blatny and his colleagues at the Swiss Federal Institute of Technology, Lausanne, and the University of Sydney, Australia, identify a common origin for these patterns. The result could lead to comprehensive continuum-mechanics models of porous media.
Blatny and his colleagues simulated a vertical 2D slice of an elastoplastic structure that was squeezed from above and below. The structure was perforated with regularly spaced square holes that composed 25% to 75% of its total area. By varying the solid area fraction and the structure’s elasticity and yield strength, the researchers examined how different porous structures deform when compressed at a constant speed. They identified six classes of compaction patterns and found that they could describe these classes entirely by two numbers that characterize the material’s properties and the speed at which the structure was compressed.
https://www.kickstarter.com/projects/2125914059/revopoint-mi…m-precison Designers, architects, engineers, we’re all collectively known as creators. The Revopoint MINI handheld 3D scanner just amplifies our creating (or rather re-creating) abilities. Designed to be about the same size as a podcasting microphone (with the tripod and all), Revopoint MINI is an industrial-grade handheld 3D scanner with a staggering precision of 0.02mm. It uses a Class 1 Blue Light that lends it its high accuracy, while still allowing it to be safe on the skin. Just hold it against the object you want to scan and wave it around and like magic, the Revopoint MINI gives you a high-accuracy 3D model, complete with tolerances, textures, and even color information. This makes it perfect for a wide degree of applications, from 3D modeling and animation to medical design, automotive design, jewelry design, even archaeology.
Our cells perform a marvel of engineering when it comes to packing information into small spaces. Every time a cell divides, it bundles up an amazing 4 meters of DNA into 46 tiny packages, each of which is only several millionths of a meter in length. Researchers from EMBL Heidelberg and the Julius-Maximilians-Universität Würzburg have now discovered how a family of DNA motor proteins succeeds in packaging loosely arranged strands of DNA into compact individual chromosomes during cell division.
The researchers studied condensin, a protein complex critical to the process of chromosome formation. Although this complex was discovered more than three decades ago, its mode of action remained largely unexplored. In 2018, researchers from the Häring group at EMBL Heidelberg and their collaborators showed that condensin molecules create loops of DNA, which may explain how chromosomes are formed. However, the inner workings by which the protein complex achieves this feat remained unknown.
Most 3D printing methods currently in use rely either on photo (light)- or thermo (heat)-activated reactions to achieve precise manipulation of polymers. The development of a new platform technology called direct sound printing (DSP), which uses soundwaves to produce new objects, may offer a third option.
The process is described in a paper published in Nature Communications. It shows how focused ultrasound waves can be used to create sonochemical reactions in minuscule cavitation regions—essentially tiny bubbles. Extremes of temperature and pressure lasting trillionths of a second can generate pre-designed complex geometries that cannot be made with existing techniques.
“Ultrasonic frequencies are already being used in destructive procedures like laser ablation of tissues and tumors. We wanted to use them to create something,” says Muthukumaran Packirisamy, a professor and Concordia Research Chair in the Department of Mechanical, Industrial and Aerospace Engineering at the Gina Cody School of Engineering and Computer Science. He is the paper’s corresponding author.
We might be consumed with CPU news with AMD’s upcoming Zen 4-based Ryzen 7,000 series CPUs, teasing a 16-core engineering sample at 5.5GHz+ but now we’re back to GPU rumors again with NVIDIA reportedly launching the higher-end GeForce RTX 4,090 first.
According to the latest from leaker “kopite7kimi”, NVIDIA will reportedly launch the GeForce RTX 4,090 first, then the GeForce RTX 4,080 and GeForce RTX 4,070 after. This would break tradition, as NVIDIA normally launches the x080 and x070 series GPUs first, followed by the x090 series GPU… but the RTX 4,090 launching first makes sense.
Researchers at the Technical University of Munich (TUM) have developed a film that not only protects wounds similar to the way a bandage does, but also helps wounds to heal faster, repels bacteria, dampens inflammation, releases active pharmaceutical ingredients in a targeted manner and ultimately dissolves by itself. This is all made possible by its dedicated design and the use of mucins, molecules which occur naturally in mucous membranes.
Conventional bandages may be very effective for treating smaller skin abrasions, but things get more difficult when it comes to soft-tissue injuries such as on the tongue or on sensitive surfaces like the intestines. What kind of material will adhere there without damaging the tissue or sticking to adjacent points? How can wounds be protected from external influences and bacteria? What kind of substance will allow cells underneath to close the wound, and then ultimately disappear without a trace?
In spite of recent progress in developing materials addressing some of the specific requirements mentioned above, engineering a multifunctional all-in-one solution remains a challenge. A team led by Oliver Lieleg, Professor of Biomechanics at the Technical University of Munich (TUM), has developed a biopolymer film that combines a wide range of different functions at the same time. In a recently published study, the biomolecular “bandage” showed highly promising results and is ready to undergo further testing and tailoring.
