Lifeboat Foundation

Interesting read on recent Gastric Cancer research. I do a lot of work with the National Esophageal Cancer (EC) Awareness Association; I can tell you that this disease is truly a killer as gastric related cancers are horrible to detect early enough and have a horrible record of reoccurring. Survival rates are some of the worst and today the rates of EC have skyrocketed especially in the younger age groups such as 25 to 35 year olds.

When you work for these foundations, read the stories from patients and their families looking for answers and help with everything from help on what types of food can their love eat and hopefully keep down for nutrition, to how can they get help with transportation to simply go to work or the doctor as meds restrictions on driving, to knowing the end is near and how to prepare, etc. The worst ones are the 27 to 36 yr old fathers and mothers whose love one is saying good bye to the person they married only recently married the year before or spent 7 years with. This is why I work for my foundations as every small step does in the end create a larger impact in the end and hopefully helps us finally beat this disease.

STING (stimulator of interferon genes) has recently been found to play an important role in host defenses against virus and intracellular bacteria via the regulation of type-I IFN signaling and innate immunity. Chronic infection with Helicobacter pylori is identified as the strongest risk factor for gastric cancer. Thus, we aim to explore the function of STING signaling in the development of gastric cancer. Immunohistochemistry was used to detect STING expression in 217 gastric cancer patients who underwent surgical resection. STING protein expression was remarkably decreased in tumor tissues compared to non-tumor tissues, and low STING staining intensity was positively correlated with tumor size, tumor invasion depth, lymph mode metastasis, TNM stage, and reduced patients’ survival. Multivariate analysis identified STING as an independent prognostic factor, which could improve the predictive accuracy for overall survival when incorporated into TNM staging system. In vitro studies revealed that knock-down of STING promoted colony formation, viability, migration and invasion of gastric cancer cells, and also led to a defect in cytosolic DNA sensing. Besides, chronic H. pylori infection up-regulated STING expression and activated STING signaling in mice. In conclusion, STING was proposed as a novel independent prognostic factor and potential immunotherapeutic target for gastric cancer.

Ring Garden is a finalist of LAGI 2016: Santa Monica, a biennial design competition that encourages interconnectivity between art, renewable energy and education.

We will need a good dose of healthy stoicism if we are to survive in the world after work. Luxury items will be significantly reduced in the world we’re imagining. Stoics like Marcus Aurelius and Seneca recommended that we adjust our desires to simple, reliable pleasures, like fresh water, decent bread, modest clothing, and good friends. Luxury pleasures are rare and unreliable so we suffer more when they fail to materialize.

But chocolate cake is delicious and diamonds are beautiful. When Plato sketched a Spartan lifestyle in the Republic, his friends accused him of designing a city for pigs not humans — and they demanded that he add spices and luxury to the imagined utopia. While I’m sensitive to this worry, I hasten to point out that many Americans are currently, and by their own initiative, downsizing their sense of the good life. The contemporary “tiny house movement” — which builds elegant housing around 1/10th the size of average homes — is already the kind of stoic adjustment that Americans will need to make when we’re all unemployed.

The future of food doesn’t have to involve animals.

That nightly indulgence is actually good for you.

A satellite that’s scheduled to launch later this year will conduct plant-growth experiments in both lunar and Martian gravity, as a way to help prepare for future human settlement of these worlds.

The Eu: CROPIS spacecraft will rotate around its own axis in low-Earth orbit, at an altitude of over 370 miles (600 kilometers). The satellite will initially produce the gravitational force of the moon on its inside for six months, and will then replicate Martian gravity for another six months.

During this time, tomato seeds will germinate and grow into small space tomatoes; 16 onboard cameras will document the plants’ progress. [Plants in Space: Photos by Gardening Astronauts].

What do the Oral-B CrossAction toothbrush, about a thousand musical compositions and even a few recent food recipes all have in common?

They were invented by computers, but you won’t find a nonhuman credited with any of these creations on U.S. patents. One patent attorney would like to see that changed.

Ryan Abbott is petitioning to address what he sees as more than a quirk in current laws but a fundamental flaw in policy that could have wide-ranging implications in areas of patent jurisprudence, economics and beyond if his proposals are adopted.

Continue reading “When the Mother of Invention Is a Machine, Who Gets Credit?” »

Scientists, have identified a brain hormone that can trigger fat burning in the gut.

Researchers from The Scripps Research Institute (TSRI) in the US found a brain hormone that specifically and selectively stimulates f at metabolism, without any effect on food intake.

The findings, published in the journal Nature Communications, in animal models could have implications for future pharmaceutical development.

Continue reading “Scientists Identify A Brain Hormone That Can Trigger Fat Burning” »

https://youtube.com/watch?v=LEx6K4P4GJc

Most of us probably don’t think too much about the foodstuffs we buy in the supermarket. But behind the scenes, today’s food production system relies on a centralized, industrial-scale supply chain that’s still dependent upon soil-based agriculture for the majority of our food crops.

In many instances, that means that food has to travel long distances from farm to table, meaning that food has lost much of its freshness and nutritional value by the time it reaches your table. There’s also a growing awareness that this model isn’t sustainable: the pressures of increasing urbanization and loss of arable land, rising populations and the increased frequency of extreme weather events like droughts and floods — brought on by climate change — means that slowly but surely, we are going to have to change the way we grow our food.

Continue reading “MIT’s Food Computers Set the Stage for Open Source Agriculture” »