Feb 27, 2024
Enhancer selectivity in space and time: from enhancer–promoter interactions to promoter activation
Posted by Dan Breeden in category: futurism
Gene regulation in animals depends chiefly on enhancers, yet the underlying mechanisms are poorly understood. This Review discusses enhancer–promoter interactions and transcription activation, focusing on how enhancer–promoter selectivity is achieved and on recent technical advances that may provide new insights into transcription activation.