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Dr. Yuval Noah Harari, macro-historian, Professor, best-selling author of “Sapiens” and “Homo Deus,” and one of the world’s most innovative and exciting thinkers, has a few hypotheses of his own on the future of humanity.

He examines what might happen to the world when old myths are coupled with new godlike technologies, such as artificial intelligence and genetic engineering.

Harari tackles into today’s most urgent issues as we move into the uncharted territory of the future.

According to Harari, we are probably one of the last generation of homo sapiens. Within a century earth will be dominated from entities that are not even human, intelligent species that are barely biological. Harari suggests the possibility that humans are algorithms, and as such Homo sapiens may not be dominant in a universe where big data becomes a paradigm.
Robots and AI will most likely replace us in our jobs once they become intelligent enough.

Although he is hopeful that AI might help us solve many problems, such as healthcare, climate change, poverty, overpopulation etc, he cautions about the possibility of an AI arms race.

Furthermore Dr. Yuval Noah Harari suggests this technology will also allow us to upgrade our brains and nervous systems. For example, humans will be able to connect their minds directly to the internet via brain implants.

The USA Government is secretly working on a real Anti Aging Pill which aims to extend peoples lifespan and improve their health. This new longevity research project even made Aubrey De Grey interested as he said in an interview. Although he’s working on other kinds of medication to make people live forever or at least to stop peoples aging.

Dr. David Sinclair’s main research interest is the epigenetics of aging, with a focus on epigenetic reprogramming of aging, NAD+ metabolism and sirtuins, and NAD+ precursors like NR and NMN. David Sinclair is also working on supplements that are supposed to slow down the aging process.

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TIMESTAMPS:
00:00 The first of its kind.
02:28 How this Pill is going to help.
04:48 Aubrey De Grey’s Opinion.
05:43 The Future of Longevity Biotechnology.
07:07 Last Words.

#aubreydegrey #longevity #aging

According to Klaus Schwab, the founder and executive chair of the World Economic Forum (WEF), the 4-IR follows the first, second, and third Industrial Revolutions—the mechanical, electrical, and digital, respectively. The 4-IR builds on the digital revolution, but Schwab sees the 4-IR as an exponential takeoff and convergence of existing and emerging fields, including Big Data; artificial intelligence; machine learning; quantum computing; and genetics, nanotechnology, and robotics. The consequence is the merging of the physical, digital, and biological worlds. The blurring of these categories ultimately challenges the very ontologies by which we understand ourselves and the world, including “what it means to be human.”

The specific applications that make up the 4-R are too numerous and sundry to treat in full, but they include a ubiquitous internet, the internet of things, the internet of bodies, autonomous vehicles, smart cities, 3D printing, nanotechnology, biotechnology, materials science, energy storage, and more.

While Schwab and the WEF promote a particular vision for the 4-IR, the developments he announces are not his brainchildren, and there is nothing original about his formulations. Transhumanists and Singularitarians (or prophets of the technological singularity), such as Ray Kurzweil and many others, forecasted these and more revolutionary developments,. long before Schwab heralded them. The significance of Schwab and the WEF’s take on the new technological revolution is the attempt to harness it to a particular end, presumably “a fairer, greener future.”

A team of physicists has discovered how DNA

DNA, or deoxyribonucleic acid, is a molecule composed of two long strands of nucleotides that coil around each other to form a double helix. It is the hereditary material in humans and almost all other organisms that carries genetic instructions for development, functioning, growth, and reproduction. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Many people develop Alzheimer’s or other forms of dementia as they get older. However, others remain sharp well into old age, even if their brains show underlying signs of neurodegeneration.

Among these cognitively resilient people, researchers have identified and amount of time spent on intellectually stimulating activities as factors that help prevent dementia. A new study by MIT researchers shows that this kind of enrichment appears to activate a called MEF2, which controls a genetic program in the brain that promotes resistance to cognitive decline.

The researchers observed this link between MEF2 and cognitive resilience in both humans and mice. The findings suggest that enhancing the activity of MEF2 or its targets might protect against age-related dementia.

Evolutionary genomics approach identifies genes that enable plants to live in the Atacama Desert, offering clues for engineering more resilient crops to face climate change.

An international team of researchers has identified genes associated with plant survival in one of the harshest environments on Earth: the Atacama Desert in Chile. Their findings, published in Proceedings of the National Academy of Sciences (PNAS), may help scientists breed resilient crops that can thrive in increasingly drier climates.

“In an era of accelerated climate change, it is critical to uncover the genetic basis to improve crop production and resilience under dry and nutrient-poor conditions,” said Gloria Coruzzi, Carroll & Milton Petrie Professor in the New York University (NYU) Department of Biology and Center for Genomics and Systems Biology, who co-led the study with Rodrigo Gutiérrez.

Rare diseases aren’t so rare. Collectively, up to 30 million Americans, many of them children, are born with one of the approximately 7,000 known rare diseases. Most of these millions of people also share a common genetic feature: their diseases are caused by an alteration in a single gene.

Many of these alterations could theoretically be targeted with therapies designed to correct or replace the faulty gene. But there have been significant obstacles in realizing this dream. The science of gene therapy has been making real progress, but pursuing promising approaches all the way to clinical trials and gaining approval from the U.S. Food and Drug Administration (FDA) is still very difficult. Another challenge is economic: for the rarest of these conditions (which is most of them), the market is so small that most companies have no financial incentive to pursue them.

To overcome these obstacles and provide hope for those with rare diseases, we need a new way of doing things. One way to do things differently—and more efficiently—is the recently launched Bespoke Gene Therapy Consortium (BGTC). It is a bold partnership of NIH, the FDA, 10 pharmaceutical companies, and several non-profit organizations [1]. Its aim: optimize the gene therapy development process and help fill the significant unmet medical needs of people with rare diseases.

It’s the dog days of summer. You bite down on a plump, chilled orange. Citrus juice explodes in your mouth in a refreshing, tingling burst. Ahh.

And congratulations—you’ve just been vaccinated for the latest virus.

That’s one of the goals of molecular farming, a vision to have plants synthesize medications and vaccines. Using genetic engineering and synthetic biology, scientists can introduce brand new biochemical pathways into plant cells—or even whole plants—essentially turning them into single-use bioreactors.

“De-Extinction” Biotechnology & Conservation Biology — Ben Novak, Lead Scientist Revive & Restore


Ben Novak is Lead Scientist, at Revive & Restore (https://reviverestore.org/), a California-based non-profit that works to bring biotechnology to conservation biology with the mission to enhance biodiversity through the genetic rescue of endangered and extinct animals (https://reviverestore.org/what-we-do/ted-talk/).

Ben collaboratively pioneers new tools for genetic rescue and de-extinction, helps shape the genetic rescue efforts of Revive & Restore, and leads its flagship project, The Great Passenger Pigeon Comeback, working with collaborators and partners to restore the ecology of the Passenger Pigeon to the eastern North American forests. Ben uses his training in ecology and ancient-DNA lab work to contribute, hands-on, to the sequencing of the extinct Passenger Pigeon genome and to study important aspects of its natural history (https://www.youtube.com/watch?v=pK2UlLsHkus&t=1s).

Ben’s mission in leading the Great Passenger Pigeon Comeback is to set the standard for de-extinction protocols and considerations in the lab and field. His 2018 review article, “De-extinction,” in the journal Genes, helped to define this new term. More recently, his treatment, “Building Ethical De-Extinction Programs—Considerations of Animal Welfare in Genetic Rescue” was published in December 2019 in The Routledge Handbook of Animal Ethics: 1st Edition.

Ben’s work at Revive & Restore also includes extensive education and outreach, the co-convening of seminal workshops, and helping to develop the Avian and Black-footed Ferret Genetic Rescue programs included in the Revive & Restore Catalyst Science Fund.

VR can soon become perceptually indistinguishable from the physical reality, even superior in many practical ways, and any artificially created “imaginary” world with a logically consistent ruleset of physics would be ultrarealistic. Advanced immersive technologies incorporating quantum computing, AI, cybernetics, optogenetics and nanotech would make this a new “livable” reality within the next few decades. Can this new immersive tech help us decipher the nature of our own “b… See more.