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Microsoft co-founder Bill Gates has been working to improve the state of global health through his nonprofit foundation for 20 years, and today he told the nation’s premier scientific gathering that advances in artificial intelligence and gene editing could accelerate those improvements exponentially in the years ahead.

“We have an opportunity with the advance of tools like artificial intelligence and gene-based editing technologies to build this new generation of health solutions so that they are available to everyone on the planet. And I’m very excited about this,” Gates said in Seattle during a keynote address at the annual meeting of the American Association for the Advancement of Science.

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Dr. Theodore Ho talks about the rapidly expanding possibilities of stem cells to be used in reversing or slowing the aging process. He discusses his previous and current work with the brain, including such methods as tissue clearing, multifiber photometry and optogenetics, and single resolution calcium imaging and control. Dr. Ho is a neuroscientist and stem cell biologist studying the mechanisms and causes of biological aging and potential strategies to slow or reverse them, in order to prevent the onset of age

Associated diseases to help us live healthier and longer lives.

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AZOKH, Nagorno-Karabakh (People of Ar)—Scholars from Britain, US, Denmark and Armenia led by Professor Levon Yepiskoposyan have been examining prehistoric caves near the village of Azokh in Artsakh (Nagorno Karabakh) and found unique artifacts from different periods, among them a tooth from a human who lived 7000 years ago. Due to the cave’s climate DNA was preserved inside the tooth and was send to Copenhagen University’s genetics department (in Denmark) for examination. The results of this inquiry have revealed that the genetic makeup of the tooth belonging to an individual 7000 years ago perfectly matches with the genetic makeup of modern Armenians.

“This is the conclusion we’ve reached after numerous excavations carried out on the territory of Karabakh, where we examined more than a dozen caves, among them the cave of Azokh and Alexan Uzes,” Yepiskoposyan said.

An American biotech company says it created a coronavirus vaccine three hours after getting access to the virus’ genetic sequence in mid-January, and now scientists are racing to get the vaccine on the market in record time.

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Inovio Pharmaceuticals is based in Pennsylvania, but scientists in its laboratory in San Diego made the discovery.

Georgia Tech Research Institute (GTRI) is looking into ways to speed up DNA-based cold storage in a $25m Scalable Molecular Archival Software and Hardware (SMASH) project.

DNA is a biopolymer molecule composed from two chains in a double helix formation, and carrying genetic information. The chains are made up from nucleotides containing one of four nucleobases; cytosine ©, guanine (G), adenine (A) and thymine (T). Both chains carry the same data, which is encoded into sequences of the four nucleobases.

GTRI senior research scientist Nicholas Guise said in a quote that DNA storage is “so compact that a practical DNA archive could store an exabyte of data, equivalent to a million terabyte hard drives, in a volume about the size of a sugar cube.”

For the first time, scientists have sequenced the entire genetic code of a giant squid.

Because the massive creature has never been captured alive, biologists have largely been left in the dark as to how the giant squid grows and behaves. After sequencing its genes, University of Copenhagen and Marine Biological Laboratory researchers found several oddities in the giant squid’s DNA — genes that are rarely found in other invertebrates, for instance — giving scientists new tools with which understand the bizarre animals.

Santa Cruz, CA February 7, 2020 —Research into the novel Wuhan seafood market pneumonia virus, the deadly “coronavirus” that has forced the Chinese government to quarantine more than 50 million people in the country’s dense industrial heartland, will be facilitated by the UC Santa Cruz Genomics Institute. The Genomics Institute’s Genome Browser team has posted the complete biomolecular code of the virus for researchers all over the world to use.

“When we display coronavirus data in the UCSC Genome Browser, it lets researchers look at the virus’ structure and more importantly work with it so they can research how they want to attack it,” said UCSC Genome Browser Engineer Hiram Clawson.

Samples of the virus have been processed in labs all over the world, and the raw information about its genetic code has been sent to the worldwide repository of genomic information at the National Institutes of Health’s National Center for Bioinformatics (NCBI) in Bethesda, Maryland.

The results are in from a human clinical trial using the CRISPR/Cas9 gene-editing system to treat cancer. The study involved editing the immune cells of three cancer patients to better fight tumors, and the results show that the treated cells persist in the body for long periods and didn’t trigger any dangerous side effects.

CRISPR allows scientists to make precise edits to the genes in living cells, removing harmful genes and introducing new beneficial ones. Animal tests of the technique have shown great promise in treating a range of diseases, such as cervical cancer, muscular dystrophy and HIV.

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