Nuclear Pore Complexes and Genome Integrity — Dr. Veronica Rodriguez-Bravo Ph.D., Sidney Kimmel Cancer Center — Jefferson Health, Thomas Jefferson University.
Dr. Veronica Rodriguez-Bravo, PhD, is Assistant Professor, Department of Cancer Biology, at the Sidney Kimmel Cancer Center, Thomas Jefferson University, in Philadelphia, PA, USA. (https://sidneykimmelcancercenter.jeffersonhealth.org/)
As smart watches are increasingly able to monitor the vital signs of health, including what’s going on when we sleep, a problem has emerged: Those wearable, wireless devices are often disconnected from our body overnight, being charged at the bedside.
“Quality of sleep and its patterns contain a lot of important information about patients’ health conditions,” says Sunghoon Ivan Lee, assistant professor in the University of Massachusetts Amherst College of Information and Computer Sciences and director of the Advanced Human Health Analytics Laboratory.
Objectives This study sought to assess the association between long working hours, psychosocial safety climate (PSC), work engagement (WE) and new major depression symptoms emerging over the next 12 months. PSC is the work climate supporting workplace psychological health.
Setting Australian prospective cohort population data from the states of New South Wales, Western Australia and South Australia.
Participants At Time 1, there were 3921 respondents in the sample. Self-employed, casual temporary, unclassified, those with working hours 35 (37% of 2850) and participants with major depression symptoms at Time 1 (6.7% of 1782) were removed. The final sample was a population-based cohort of 1084 full-time Australian employees.
“I realized that in the middle-dose group, which is the one that mattered for the no-effects level, they had conveniently left out one of the two baseline measurement days,” said Sheppard. “The outrageous thing was that the group they declared as NOEL was only that because they left out data from their analysis.” In a peer-reviewed paper published in October 2020, Sheppard and her colleagues concluded that “the omission of valid data without justification was a form of data falsification.”
In any case, bifenthrin was not the only pesticide that dodged testing to see if it presented dangers. The EPA’s pesticide office granted 972 industry requests to waive toxicity tests between December 2011 and May 2018, 89 percent of all requests made. Among the tests on pesticides that were never performed were 90 percent of tests looking for developmental neurotoxicity, 92 percent of chronic cancer studies, and 97 percent of studies looking at how pesticides harm the immune system.
By law, the companies that submit their products for review pay for these tests, and in a presentation about the waivers last year, Anna Lowit, a senior science adviser in the office, emphasized the savings to these companies: more than $300 million. Lowit also noted that animal lives were saved — a goal that the Trump administration and the chemical industry prioritized within the agency. The EPA developed the guidelines for waiving the tests along with BASF, Corteva, and Syngenta, pesticide manufacturers that all stand to benefit significantly from having their products bypass toxicity testing.
According to recent Occupational Safety and Health Administration data, workers at Amazon fulfillment centers were seriously injured about twice as often as employees in other warehouses. To improve workplace safety, Amazon has been increasing its investment in robotic helpers to reduce injuries among its employees. With access granted for the first time ever, “Sunday Morning” correspondent David Pogue visited the company’s secret technology facility near Seattle to observe some of the most advanced warehouse robots yet developed, and to experience how high-tech tools are being used to aid human workers.
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Sanofi will apply Google’s artificial intelligence (AI) and cloud computing capabilities toward developing new drugs, through a collaboration whose value was not disclosed.
The companies said they have agreed to create a virtual Innovation Lab to “radically” transform how future medicines and health services are developed and delivered.
Sanofi has articulated three goals for the collaboration with Google: better understand patients and diseases, increase Sanofi’s operational efficiency, and improve the experience of Sanofi patients and customers.
In patients with mild cognitive impairment, taking lipophilic statins more than doubles their risk of developing dementia compared to those who do not take statins. According to research presented at the Society of Nuclear Medicine and Molecular Imaging 2021 Annual Meeting, positron emission tomography (PET) scans of lipophilic statin users revealed a highly significant decline in metabolism in the area of the brain that is first impacted by Alzheimer’s disease.
Statins are medications used to lower cholesterol and reduce the risk of heart attack or stroke. They are the most commonly used drugs in the developed world, and nearly 50 percent of Americans over age 75 use a statin. Different types of statins are available based on a patient’s health needs, including hydrophilic statins that focus on the liver and lipophilic statins that are distributed to tissues throughout the body.
Exercise and supplements are both great, but if you are constantly feeding your system with home made stimulants that your body produces, you may be fighting an uphill battle. I experienced just that recently, I seemed to be forever on one social media platform or another constantly, under the excuse of promoting my videos, and it really took its toll. So, I just had a few weeks off, reading, exercising, relaxing outside, when the sun was out that is, and going for walks in nature…and now it is your turn. In Attention Span Is Decreasing, I look at how our modern lifestyles, with all their trappings and perks, can have the opposite effect to the one we are after, and how you can start to take back control. Mute alerts, use the flight mode, stick it in a drawer and embrace the 20−5−3 rule, to live not just longer, but happier, and healthier, both in body and mind, because they are inextricably linked. And if you want to know it all in a bit more depth, check out this video on my channel.
In Attention Span Is Decreasing, we will learn how our modern lifestyles, with all their trappings and perks, can have the opposite effect to the one we are…
Still the comic relief til about December 31, 2024. By 2035 curing everything, already in the early stages towards that.
Giovanni Traverso, an MIT assistant professor of mechanical engineering, a gastroenterologist at Brigham and Women’s Hospital, and also the senior author of the study said, that they were actively working on robots that can help provide health care services to maximize the safety, of both the patients and the health care workforce.
Traverso and his colleagues after the Covid-19 began last year, worked towards reducing interaction between the patients and the health care workers. In this process, they collaborated with Boston Dynamics in creating mobile robots that can interact with patients who waited in the emergency department.
New research has discovered that common artificial sweeteners can cause previously healthy gut bacteria to become diseased and invade the gut wall, potentially leading to serious health issues.
The study, published in the International Journal of Molecular Sciences, is the first to show the pathogenic effects of some of the most widely used artificial sweeteners—saccharin, sucralose, and aspartame—on two types of gut bacteria, E. coli (Escherichia coli) and E. faecalis (Enterococcus faecalis).
