Lifeboat Foundation

MIT professor Dina Katabi is building a gadget that can sit in one spot and track everything from breathing to walking, no wearables required.

A new study on adult neurogenesis and Alzheimer’s disease.

According to a study led by scientists at Massachusetts General Hospital, exercise-induced neurogenesis improves cognition in a mouse model of Alzheimer’s disease, yielding more benefits than drug-induced adult neurogenesis. The scientists were able to figure out the difference between the two types of induced neurogenesis and pharmacologically reproduce the same benefits provided by exercise [1].

Study abstract

Continue reading “Exercise Induces Adult Neurogenesis and Ameliorates Alzheimer’s Disease in Mice” »

An incurable affliction that gradually destroys a person’s ability to walk, speak, and eventually breathe can also deteriorate the mind, new research suggests. People with amyotrophic lateral sclerosis (ALS) are more likely to have other mental and behavioral health problems than people without the condition, the study found.

ALS, also called Lou Gehrig’s disease, is a progressive neurologic condition that affects some 20,000 Americans at any one time. In ALS, a person’s motor neurons throughout their body and brain steadily die off. These neurons are responsible for helping us carry out voluntary movement.

Today, we want to let you know that the documentary Paywall: The Business of Scholarship is now available in both English and Russian. This is a documentary exploring the crisis in scientific journal publication and the excessive fees that some publishers charge to access knowledge.

Holding scientific knowledge to ransom

Continue reading “Paywall: The Business of Scholarship Documentary in English and Russian” »

Utilizing new mobile application technology, researchers at The University of New Mexico found that medical cannabis provides immediate symptom relief across dozens of health symptoms with relatively minimal negative side effects.

In two recent studies titled, “Patient-Reported Symptom Relief Following Medical Cannabis Consumption,” and “Effectiveness of Raw, Natural Medical Cannabis Flower for Treating Insomnia under Naturalistic Conditions” published in the journals, Frontiers in Pharmacology and Medicines, respectively, UNM Department of Psychology Associate Professor Jacob Miguel Vigil and UNM Department of Economics Assistant Professor Sarah See Stith, document that patients experienced statistically and clinically significant therapeutic benefits when they used cannabis for symptoms ranging from chronic pain to insomnia.

These studies analyzed data collected with the Releaf App, developed by co-authors Franco Brockelman, Keenan Keeling and Branden Hall and currently, the largest repository of user-entered information on the consumption and effects of cannabis use in the United States with nearly 100,000 recorded user sessions.

Continue reading “Study shows medical cannabis effective in treating a wide range of health conditions” »

On any given day, Zoubaida Salman instructs a classroom of 15-year-olds at the Sur Baher Girls School in East Jerusalem, where she has served as the science teacher and Environment and Health Coordinator for the past 22 years. One of the most important lessons comes from their backyard: water is scarce and precious in this region.

Water shortages can lead to major sanitation issues at schools, so students have to play an active role in managing it. At Sur Baher, the most significant use of water is for flushing toilets, which stop working if there is not enough water. If the water runs out, school administrators must buy it from the city. In other regions, the schools even close because of water shortages.

A team of scientists with the NASA DEVELOP program is helping address these water shortages by collaborating with a nonprofit called Water Resources Action Project(WRAP). WRAP designs and constructs rainwater harvesting systems for schools in the Middle East to capture rainfall during the five-month rainy season for use later. Selecting a geographically promising area is time-consuming and tedious work though for the small, volunteer-based team. The NASA DEVELOP team is using satellite data to help WRAP more easily identify suitable locations for the rainwater harvesting systems.

Researchers don’t know much about whether people who aren’t diabetic should avoid having glucose spikes after meals, or whether, by contrast, average glucose levels are more important — things that need to be studied, he said.

“They’re right to be asking it. I don’t have data to give guidance on how to interpret it,” Bergenstal said. “I think they’re right to say it can’t be bad if I keep my blood sugars more stable. It’s a reasonable assumption, but we don’t have the data for it.”

It’s generally accepted that non-diabetics are better able to regulate their glucose levels. A higher than normal level, meanwhile, indicates prediabetes. But a new study out of Stanford University in late July that used CGMs on 57 participants, including diabetics and non-diabetics, had a surprising finding.

Continue reading “Non-diabetics are using diabetes technology to track their blood sugar and improve their health” »

The Alzheimer’s Hypothesis

Introduction

Continue reading “The Alzheimer's Hypothesis” »

Alzheimer’s disease is one of the biggest medical challenges of our time. About 30 million people worldwide are living with Alzheimer’s disease, and the numbers are predicted to increase to 100 million by 2050 if we do not find effective prevention or treatment strategies (1). Substantial evidence suggests that leading a healthy lifestyle, including regular exercise, may lower the risk of developing Alzheimer’s disease. However, the mechanisms through which exercise protects the brain and whether we could bottle these as a treatment remain controversial. On page 991 of this issue, Choi et al. (2) reveal that in a mouse model of Alzheimer’s disease, exercise improves memory through a combination of encouraging neurogenesis in the hippocampus and increasing the levels of brain-derived neurotrophic factor (BDNF), a growth factor that supports neuronal survival. Their findings suggest that agents that promote both BDNF signaling and neurogenesis might be effective in preventing or treating Alzheimer’s disease.

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