Lifeboat Foundation

Amazing — fighting cancer with a new drug that self-assembles from individual cells that interact with each other into a complex structure through weak supramolecular interactions.

The first multicellular organism, Volvox, evolved from self-assembly of individual cells. Inspired by this organism, researchers from Brigham and Women’s Hospital have developed a novel approach for treating cancer. Drawing from the lessons of evolution, they designed anti-cancer molecules that can self-assemble with each other into a complex structure through weak supramolecular interactions. The complex, supramolecular therapeutics home into the tumor, increasing anticancer efficacy and reducing side effects.

To engineer the supramolecular therapeutics, the researchers developed a first-of-its-kind computational algorithm that simulates how anticancer molecules interact with each other at the molecular and atomic level. This understanding led to the design of the most optimal building blocks that can click with each other like LEGO blocks to form the supramolecular therapeutic. The researchers have named this computational algorithm Volvox after the biological organism.

Ashish Kulkarni, PhD, an instructor in the Division of Engineering in the Department of Medicine at the Brigham and Women’s Hospital, and the lead author of the paper published in September issue of ACS Nano, said, “The algorithm saves a lot of time during the development of next generation cancer therapy. Before we even go into experimental analysis, we are able to see whether or not there is a high enough concentration of the drug for the treatment to be effective. We hope that our method can eventually be used to treat many different types of cancer.”

Zoom out far enough, and the Universe is a pretty homogenous place.

For vessels operating at sea, avoiding collisions is a basic operational requirement. When those vessels are operated by humans, collision avoidance is part of basic operator training. And when those vessels become highly autonomous, collision avoidance must be incorporated into complex autonomy algorithms that must be thoroughly tested before the vessels enter the water.

Most people might not drool over Oppo phones, but they’re going to get a feature that might get those salivary glands pumping. This morning at Mobile World Congress, the company showed off its new SuperVOOC quick-charging technology. If real-world results are as promising as they say, Oppo fans will be able to fully charge some of their devices in 15 minutes. No, seriously.

Oppo says that’s about how much time it’ll take to charge a dead 2,500mAh battery to 100 percent, and that the technology will work over traditional micro-USB and USB Type-C cables. That’s even faster than what we’ve seen out of Qualcomm’s most recent Quick Charge 3.0 demos — the fast-charging technology baked into chipsets like the Snapdragon 820 can get a smartphone from bone-dry to 80 percent in around 35 minutes. Of course, it’s sort of no surprise that Oppo can squeeze better performance out of their system — it’s more or less proprietary Oppo, so the company has full control over the battery, silicon and software involved. That’s the sort of end-to-end control that helped Huawei figure out how to supercharge smartphones, too.

In some cases, you’ll be able to get a full charge in less than 15 minutes. An Oppo hype man plugged a metal-encased reference device into a charger and continued his spiel in Mandarin. Less than ten minutes later — after he discussed an algorithm that varies current to maximize charging efficiency while keeping temperatures low — the phone was back up to 100 percent. Our natural skeptics can’t help suspect this was just a staged demo for the show, so here’s hoping we soon get to test a SuperVOOC phone for ourselves.

MIT has used machine learning to create video from still images, and the results are pretty impressive. As you can see from the above image, there’s a lot of natural form to the movement in the videos.

The system “learns” types of videos (beach, baby, golf swing…) and, starting from still images, replicates the movements that are most commonly seen in those videos. So the beach video looks like it has crashing waves, for instance.

But like other machine-generated images, these have limitations. The first is size: what you see above is the extent to which the program can render its video. Length is also an issue: only about a second of video gets produced.

Continue reading “Machine-Learning Algorithm Generates Videos From Stills” »

Brain is the new product from Jerry Yue which is based on Advanced algorithm. According to Yue, Brain will work as a personal virtual assistant for each user by having users input not just a profile of who they are, but what they do, and what they want to do in the future.

“Fifty years after the show aired, Star Trek’s fictional tricorder is far from becoming a reality. But a $10 million prize from the XPRIZE Foundation is hoping to motivate inventors to create one quickly.”

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Feynman told us clearly: “Science is the belief in the ignorance of experts.” Check anything from first principles and experience, ignoring no logical holes, and that is science. Cargo Cult Science arises when the opposing arguments aren’t emphasized. Experts then form and pass down firm beliefs that are delusions. Cargo Cult science is like a perfect replica radio made all of wood: it may have all the trappings of degrees and chairs and journals, but it is missing the key ingredient and won’t function.[1][2]

Vaccine science is cargo cult science according to Feynman’s definition. There are a ton of peer reviewed papers demonstrating that vaccine aluminum is damaging, that vaccines are full of contaminants, that they can disrupt brain and immune system development, that the smallpox vaccine was ineffective, the polio vaccine is of questionable utility, other vaccines’ immunity wanes after only a few years. They never rebut as you can easily verify yourself by examining the citation list here for opposition and then searching the vaccine survey pdfs for the cites. They just ignore it.[3][4][5]

Climate science is cargo cult science. Climate “scientists” have been known to “hide” their own most interesting data, the data contradicting the prevailing theory which is what Feynman said a scientist should emphasize most prominently[6][7]. Alternative theories and methodological objections are ignored or white washed. (Search the IPCC reports for discussion of the opposition.) To say a science is cargo cult science is not to say that there are no papers published in it that are science, but it is to say one should repose zero or negative confidence in any pronouncement one has not personally verified from first principles.

http://TruthSift.com supports Feynman’s model of science applied to everything. Just as in mathematical practice, you can post proofs and refutations. But nothing is considered established unless every proposed refutation has an established counter-refutation. No proposed refutation can be ducked, and anybody who believes they have a rational objection may post it (and see the establishment statuses reflect the objection in real time). Try it out. Check out (and please contribute to) the ongoing diagrammings of the vaccine/climate science etc literatures. When they have passed through true logical review, confronting all the opposing arguments, what remains will be a genuine science.

[1] Richard P Feynman, What is Science? (1968) http://www-oc.chemie.uni-regensburg.de/diaz/img_diaz/feynman…nce_68.pdf
[2] Richard P Feynman, CARGO CULT SCIENCE (adapted from Caltech Commencement Address 1974) https://www.lhup.edu/~DSIMANEK/cargocul.htm
[3] Eric Baum The Top Ten Reasons I Believe Vaccine Safety Is an Epic Mass Delusion (2016) https://lifeboat.com/blog/2016/06/the-top-ten-reasons-i-beli…s-delusion
[4] TruthSift Topic: Are Vaccines Safe? (2016) http://truthsift.com/search_view?statement=Vaccines-are-Safe…p;nid=4083
[5] TruthSift Topic: The Evidence is Weak Vaccines Have Saved More Lives than They Have Cost (2016), http://truthsift.com/search_view?topic=The-Evidence-Is-Weak-…amp;id=520
[6] Climate data hidden both early (data showing very rapid rise before 1500) and in 20th century (showing decline): https://climateaudit.org/2011/03/21/hide-the-decline-the-other-deletion/
[7] More data contradicting theory hidden. https://climateaudit.org/2011/12/01/hide-the-decline-plus/

Beauty is in the eye of the beholder, but for one contest the beholders are AI. Beauty.AI used 5 robots to judge 6,000 selfies and choose winners for an international beauty contest.