Lifeboat Foundation

In this episode, David and Peter discuss aging as a disease, the technology needed to reverse aging, and tips and tricks to increase your lifespan.

David Sinclair is a biologist and academic known for his expertise in aging and epigenetics. Sinclair is a genetics professor and the Co-Director of Harvard Medical School’s Paul F. Glenn Center for Biology of Aging Research. He’s been included in Time100 as one of the 100 Most Influential People in the World, and his research has been featured all over the media. Besides writing a New York Times Best Seller, David has co-founded several biotech companies, a science publication called Aging, and is an inventor of 35 patents.
Read David’s book, Lifespan: Why We Age-and Why We Don’t Have To: https://a.co/d/85H3Mll.

Continue reading “Why Aging is a Disease With David Sinclair | EP #18 Moonshots and Mindsets” »

Year 2022 😗

Plastic foam like Styrofoam is a ubiquitous, harmful and nearly immortal single-use material that is long overdue for a good, green replacement — and Cruz Foam is here to supply it. The startup creates a durable yet backyard-compostable packing foam out of shrimp shells produced (and discarded) by the seafood industry. It recently extended its seed round to accommodate the interests of Leonardo DiCaprio and Ashton Kutcher, and is scaling up to meet the demands of its first major customer, Whirlpool.

I met Cruz Foam co-founder John Felts during the memorable Accelerator at Sea hosted by the Sustainable Ocean Alliance. His pitch made perfect sense: create a biodegradable alternative to expanded polystyrene (EPS) foam using a material provided in abundance by nature.

Continue reading “Cruz Foam taps DiCaprio and Kutcher in $3.5M greentech seed” »

New approaches to the biology of senescence can make lives longer and healthier.

A study using 30 years of data links good hydration to a lower risk of developing some chronic illnesses and premature aging.

When it comes to longevity in the animal kingdom, the Naked mole-rat is often touted as one of the longest living animals known to man, and some say that they functionally do not age, only ever dying of disease or predation. In this article we will investigate these claims, and discover what exactly is so exciting about these aesthetically challenged rodents which has made so many researchers so optimistic about the future of human longevity.

Are Naked Mole-Rats Immortal?

Let’s dispel one of the largest misconceptions about naked mole-rats (Heterocephalus glaber) before we dive into what makes these rodents so interesting. No, naked mole-rats are not immortal in any sense of the word. First documented in 1,842 by German naturalist Eduard Rüppell, we have formally studied this species of rodent for over 180 years, and we have yet to see any immortal naked-mole rats running around, in the wild or otherwise. Neither have we seen a naked mole-rat coming close to the longevity enjoyed by our own species, let alone the longevity enjoyed by other longer lived species such as the giant tortoise. However, it is not the lifespan itself that is so remarkable about the naked mole-rat, but rather its relative longevity compared to other rodents that makes the naked mole-rat so interesting.

“Proper hydration may slow down aging and prolong a disease-free life.”

It is an indisputable fact that drinking water is beneficial for our health. In addition to its contribution to metabolism, it also plays an important role in keeping the skin moist. According to the National Institutes of Health’s (NIH) new study, drinking water also links people to age in a healthy way.

As stated in the release, researchers looked at the relationship between several health markers and blood salt levels, which rise when fluid intake declines. The study included health information acquired from 11,255 participants over a 30-year period.

Continue reading “Scientists have revealed a link between drinking enough water and aging” »

Summary: Study finds a link between poor hydration in adults and an increased risk of chronic health conditions and advanced biological aging.

Source: NIH

Adults who stay well-hydrated appear to be healthier, develop fewer chronic conditions, such as heart and lung disease, and live longer than those who may not get sufficient fluids, according to a National Institutes of Health study published in eBioMedicine. .

New research in the journal Nature Aging takes a page from the field of renewable energy and shows that genetically engineered mitochondria can convert light energy into chemical energy that cells can use, ultimately extending the life of the roundworm C. elegans. While the prospect of sunlight-charged cells in humans is more science fiction than science, the findings shed light on important mechanisms in the aging process.

“We know that mitochondrial dysfunction is a consequence of aging,” said Andrew Wojtovich, Ph.D., associate professor of Anesthesiology and Perioperative Medicine and Pharmacology & Physiology at the University of Rochester Medical Center and senior author of the study.

“This study found that simply boosting metabolism using light-powered mitochondria gave laboratory worms longer, healthier lives. These findings and new research tools will enable us to further study mitochondria and identify new ways to treat age-related diseases and age healthier.”

Findings underline the importance of a strength-based rather than a deficit-based focus on aging and older adults.

What are the keys to “successful” or optimal aging? A new study followed more than 7,000 middle-aged and older Canadians for approximately three years to identify the factors linked to well-being as we age.

They found that those who were female, married, physically active, and not obese and those who had never smoked, had higher incomes, and who did not have insomnia, heart disease or arthritis, were more likely to maintain excellent health across the study period and less likely to develop disabling cognitive, physical, or emotional problems.