Lifeboat Foundation

New York’s Gorbunova Aging Research Center team is encouraged by frailty results from SIRT6 activator trial.

SIRT6, the so-called “longevity sirtuin” has been making rather a name for itself.

SIRT6 is a protein with an important job. It is vital for both normal base excision repair and double-strand break repair of DNA damage – damage that can lead to genomic instability, which ultimately contributing to aging. These repairs decline with age but can be boosted with SIRT6 [1].

Continue reading “Longevity sirtuin clinical trial teases promising results” »

Circa 2018

New research has opened doors to using the gene-editing tool CRISPR to stop cancer cells from dividing indefinitely.

Innovative Solutions For Unmet Needs Of Older Adults & Their Caregivers — Keith Camhi, Managing Director, Techstars Future of Longevity Accelerator — A Partnership With Melinda Gates Pivotal Ventures.

Keith Camhi is Managing Director, Techstars Future of Longevity Accelerator (https://www.techstars.com/accelerators/longevity), a program, run in partnership with Pivotal Ventures (https://www.pivotalventures.org/), an investment and incubation company created by Melinda French Gates, focusing on innovative solutions to address the unmet needs of older adults and their caregivers. The longevity accelerator core program themes include: Caregiver Support, Care Coordination, Aging in Place, Financial Wellness and Resilience, Preventive Health (both Physical and Cognitive), and Social Engagement.

Continue reading “Keith Camhi — Techstars Future of Longevity Accelerator — Innovative Solutions For Older Adults” »

I don’t buy the Jeanne Calment story.

How can we live longer and be healthier? These startups are trying to extend our lives.
✱ Download the Dizraptor app to invest in technologies of the future https://dizraptor.onelink.me/1kIK/samumed.

Continue reading “TOP 5 Longevity Startups. Who Will Make Us Immortal?” »

Within minutes of the final heartbeat, a cascade of biochemical events triggered by a lack of blood flow, oxygen, and nutrients begins to destroy a body’s cells and organs. But a team of Yale scientists has found that massive and permanent cellular failure doesn’t have to happen so quickly.

The researchers stressed that additional studies are necessary to understand the apparently restored motor functions in the animals, and that rigorous ethical review from other scientists and bioethicists is required.

The experimental protocols for the latest study were approved by Yale’s Institutional Animal Care and Use Committee and guided by an external advisory and ethics committee.

Continue reading “Yale-developed technology restores cell, organ function in pigs after death” »

A study into bone loss in astronauts returning from long spaceflights has shown that some may have incomplete bone recovery even after one year back on Earth, with sustained losses equivalent to 10 years of normal age-related bone loss on Earth.

An organism uses programmed cell death as a critical tool to maintain its health. Various stress responses are triggered when a cell does not operate as it should. These responses aim to bring back the original cell function.

One example is the process known as autophagy, in which a cell partly digests itself in order to acquire energy that it can utilize for its own repair. Should these efforts fail, the cell dies. This enables the body to combat conditions including infections, diabetes, cancer, and neurodegeneration.

Circa 2020 Reversing the biological clock to essentially reverse aging.

Expression of three Yamanaka transcription factors in mouse retinal ganglion cells restores youthful DNA methylation patterns, promotes axon regeneration after injury, and reverses vision loss in a mouse model of glaucoma and in aged mice, suggesting that mammalian tissues retain a record of youthfu…